Abstract: This invention relates to combination therapies comprising an EZH2 inhibitor and a chemotherapeutic agent, and associated pharmaceutical compositions, methods of treatment, and pharmaceutical uses.

Abstract: This invention relates to combination therapies comprising an EZH2 inhibitor and a chemotherapeutic agent, and associated pharmaceutical compositions, methods of treatment, and pharmaceutical uses.

Abstract: Examples of the present disclosure describe systems and methods relating to conversation state management using frame tracking. In an example, a frame may represent one or more constraints (e.g., parameters, variables, or other information) received from or generated as a result of interactions with a user. Consequently, each frame may represent one or more states of an ongoing conversation. When the user provides new or different information, a new frame may be created to represent the now-current state of the conversation. The previous frame may be retained for later access by what is referred to herein as a “dialog agent,” which is the portion of the system that can search and use previous state-related information. When an utterance is received, a frame to which the utterance relates may be identified. Thus, the dialog agent may track multiple states simultaneously, thereby enabling conversation features that were not previously possible.

Abstract: Described herein are systems and methods for providing a natural language generator in a spoken dialog system that considers both lexicalized and delexicalized dialog act slot-value pairs when translating one or more dialog act slot-value pairs into a natural language output. Each slot and value associated with the slot in a dialog act are represented as (dialog act+slot, value), where the first term (dialog act+slot) is delexicalized and the second term (value) is lexicalized. Each dialog act slot-value representation is processed to produce at least one delexicalized sentence as an output. A lexicalized sentence is produced by replacing each delexicalized slot with the value associated with the delexicalized slot.

Abstract: Examples of the present disclosure describe systems and methods relating to conversation state management using frame tracking. In an example, a frame may represent one or more constraints (e.g., parameters, variables, or other information) received from or generated as a result of interactions with a user. Consequently, each frame may represent one or more states of an ongoing conversation. When the user provides new or different information, a new frame may be created to represent the now-current state of the conversation. The previous frame may be retained for later access by what is referred to herein as a “dialogue agent,” which is the portion of the system that can search and use previous state-related information. When an utterance is received, a frame to which the utterance relates may be identified. Thus, the dialogue agent may track multiple states simultaneously, thereby enabling conversation features that were not previously possible.

Abstract: Described herein are systems and methods for providing a natural language generator in a spoken dialogue system that considers both lexicalized and delexicalized dialogue act slot-value pairs when translating one or more dialogue act slot-value pairs into a natural language output. Each slot and value associated with the slot in a dialogue act are represented as (dialogue act+slot, value), where the first term (dialogue act+slot) is delexicalized and the second term (value) is lexicalized. Each dialogue act slot-value representation is processed to produce to produce at least one delexicalized sentence as an output. A lexicalized sentence is produced by replacing each delexicalized slot with the value associated with the delexicalized slot.