Patents by Inventor Shilong Yang

Shilong Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10889606
    Abstract: A method for preparing a biflavone-iron complex, includes using the amentoflavone as the ligand and the ferric ion as the central ion, the amentoflavone-iron complex is obtained by reaction, and the structure of the complex is characterized by infrared spectroscopy, UV-vis absorption spectroscopy and high resolution mass spectrometry. Meanwhile, the antitumor and antioxidant activities of the amentoflavone-iron complex are studied in the present invention. MTT method shows that the amentoflavone-iron complex has a relatively good antitumor activity, and the antitumor activity thereof is stronger than that of the amentoflavone. Pyrogallol auto-oxidation method and ABTS method show that the antioxidative activity of the amentoflavone-iron complex is stronger than that of the amentoflavone itself.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: January 12, 2021
    Assignee: NANJING FORESTRY UNIVERSITY
    Inventors: Li Xu, Fuliang Cao, Shilong Yang
  • Patent number: 10815254
    Abstract: The present invention discloses a biflavone-zinc complex, a preparation method and application thereof. In the present invention, using the amentoflavone as the ligand and the zinc ion as the central ion, the amentoflavone-zinc complex is obtained by reaction, and the structure of the complex is characterized by infrared spectroscopy, UV-vis absorption spectroscopy and high resolution mass spectrometry. Meanwhile, the antitumor and antioxidant activities of the amentoflavone-zinc complex are studied in the present invention. MTT method shows that the amentoflavone-zinc complex has better antitumor activity, and the antitumor activity thereof is stronger than that of the amentoflavone. Pyrogallol auto-oxidation method and ABTS method show that the antioxidative activity of the amentoflavone-zinc complex is stronger than that of the amentoflavone itself.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: October 27, 2020
    Assignee: NANJING FORESTRY UNIVERSITY
    Inventors: Fuliang Cao, Li Xu, Shilong Yang
  • Patent number: 10815252
    Abstract: A biflavone-copper complex, a preparation method and application thereof are disclosed. The biflavone-copper complex has the following structural formula: wherein, X is NO3? or Cl?. A method of preparing the biflavone-copper complex includes the following steps: dissolving a copper salt in an alcohol and then adding into a biflavone alcoholic solution, controlling pH to 5-7; under heating and stirring, performing a reaction for 2-5 h to form a precipitate; filtering the precipitate, washing the precipitate with alcohol and water, recrystallizing the precipitate using dimethyl sulfoxide as a solvent, and drying the precipitate to obtain the biflavone-copper complex. The biflavone-copper complex is used for preparing an antitumor drug and/or an antioxidant drug.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: October 27, 2020
    Assignee: NANJING FORESTRY UNIVERSITY
    Inventors: Li Xu, Shilong Yang, Zhong Li
  • Patent number: 10808001
    Abstract: A method for preparing a biflavone-cobalt complex includes using the amentoflavone as the ligand and the cobalt ion as the central ion, the amentoflavone-cobalt complex is obtained by reaction, and the structure of the complex is characterized by infrared spectroscopy, UV-vis absorption spectroscopy and high resolution mass spectrometry. Meanwhile, the antitumor and antioxidant activities of the amentoflavone-cobalt complex are studied in the present invention. MTT method shows that the amentoflavone-cobalt complex has better antitumor activity, and the antitumor activity thereof is stronger than that of the amentoflavone. Pyrogallol auto-oxidation method, ABTS method and FRAP method show that the antioxidan activity of the amentoflavone-cobalt complex is stronger than that of the amentoflavone itself. The formation of the flavonoid-cobalt complex enhances the antitumor and anti-oxidation activities of the amentoflavone, and is expected to be used in the development of drugs.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: October 20, 2020
    Assignee: NANJING FORESTRY UNIVERSITY
    Inventors: Guibin Wang, Li Xu, Shilong Yang, Fuliang Cao
  • Publication number: 20200247825
    Abstract: The present invention discloses a biflavone-zinc complex, a preparation method and application thereof. In the present invention, using the amentoflavone as the ligand and the zinc ion as the central ion, the amentoflavone-zinc complex is obtained by reaction, and the structure of the complex is characterized by infrared spectroscopy, UV-vis absorption spectroscopy and high resolution mass spectrometry. Meanwhile, the antitumor and antioxidant activities of the amentoflavone-zinc complex are studied in the present invention. MTT method shows that the amentoflavone-zinc complex has better antitumor activity, and the antitumor activity thereof is stronger than that of the amentoflavone. Pyrogallol auto-oxidation method and ABTS method show that the antioxidative activity of the amentoflavone-zinc complex is stronger than that of the amentoflavone itself.
    Type: Application
    Filed: February 13, 2018
    Publication date: August 6, 2020
    Applicant: NANJING FORESTRY UNIVERSITY
    Inventors: Fuliang CAO, Li XU, Shilong YANG
  • Publication number: 20200239506
    Abstract: A method for preparing a biflavone-iron complex, includes using the amentoflavone as the ligand and the ferric ion as the central ion, the amentoflavone-iron complex is obtained by reaction, and the structure of the complex is characterized by infrared spectroscopy, UV-vis absorption spectroscopy and high resolution mass spectrometry. Meanwhile, the antitumor and antioxidant activities of the amentoflavone-iron complex are studied in the present invention. MTT method shows that the amentoflavone-iron complex has a relatively good antitumor activity, and the antitumor activity thereof is stronger than that of the amentoflavone. Pyrogallol auto-oxidation method and ABTS method show that the antioxidative activity of the amentoflavone-iron complex is stronger than that of the amentoflavone itself.
    Type: Application
    Filed: February 13, 2018
    Publication date: July 30, 2020
    Applicant: NANJING FORESTRY UNIVERSITY
    Inventors: Li XU, Fuliang CAO, Shilong YANG
  • Publication number: 20200239507
    Abstract: A method for preparing a biflavone-cobalt complex includes using the amentoflavone as the ligand and the cobalt ion as the central ion, the amentoflavone-cobalt complex is obtained by reaction, and the structure of the complex is characterized by infrared spectroscopy, UV-vis absorption spectroscopy and high resolution mass spectrometry. Meanwhile, the antitumor and antioxidant activities of the amentoflavone-coablt complex are studied in the present invention. MTT method shows that the amentoflavone-cobalt complex has better antitumor activity, and the antitumor activity thereof is stronger than that of the amentoflavone. Pyrogallol auto-oxidation method, ABTS method and FRAP method show that the antioxidan activity of the amentoflavone-cobalt complex is stronger than that of the amentoflavone itself. The formation of the flavonoid-cobalt complex enhances the antitumor and anti-oxidation activities of the amentoflavone, and is expected to be used in the development of drugs.
    Type: Application
    Filed: February 13, 2018
    Publication date: July 30, 2020
    Applicant: NANJING FORESTRY UNIVERSITY
    Inventors: Guibin WANG, Li XU, Shilong YANG, Fuliang CAO
  • Publication number: 20200010483
    Abstract: A biflavone-copper complex, a preparation method and application thereof are disclosed. The biflavone-copper complex has the following structural formula: wherein, X is NO3? or Cl?. A method of preparing the biflavone-copper complex includes the following steps: dissolving a copper salt in an alcohol and then adding into a biflavone alcoholic solution, controlling pH to 5-7; under heating and stirring, performing a reaction for 2-5 h to form a precipitate; filtering the precipitate, washing the precipitate with alcohol and water, recrystallizing the precipitate using dimethyl sulfoxide as a solvent, and drying the precipitate to obtain the biflavone-copper complex. The biflavone-copper complex is used for preparing an antitumor drug and/or an antioxidant drug.
    Type: Application
    Filed: February 13, 2018
    Publication date: January 9, 2020
    Applicant: NANJING FORESTRY UNIVERSITY
    Inventors: Li XU, Shilong YANG, Zhong LI
  • Patent number: 7664489
    Abstract: A method for a communication between two cellular phones is provided, in which the communication between the cellular phones includes an intercom communication and a telephone communication. The method includes steps of providing a telephone number of one cellular phone and an intercom number associated with the telephone number in the other cellular phone, dialing the telephone number of the one cellular phone by the other cellular phone to activate a calling to the intercom number associated with the telephone number, determining whether the cellular phones are within an intercom communication area, and performing the intercom communication therebetween while the cellular phones are within an intercom communication area, or performing the telephone communication therebetween while the cellular phones are without an intercom communication area.
    Type: Grant
    Filed: January 30, 2006
    Date of Patent: February 16, 2010
    Assignee: Inventec Appliances Corp.
    Inventors: Chengshing Lai, Shilong Yang
  • Publication number: 20060172728
    Abstract: A method for a communication between two cellular phones is provided, in which the communication between the cellular phones includes an intercom communication and a telephone communication. The method includes steps of providing a telephone number of one cellular phone and an intercom number associated with the telephone number in the other cellular phone, dialing the telephone number of the one cellular phone by the other cellular phone to activate a calling to the intercom number associated with the telephone number, determining whether the cellular phones are within an intercom communication area, and performing the intercom communication therebetween while the cellular phones are within an intercom communication area, or performing the telephone communication therebetween while the cellular phones are without an intercom communication area.
    Type: Application
    Filed: January 30, 2006
    Publication date: August 3, 2006
    Inventors: Chengshing Lai, Shilong Yang