Patents by Inventor Shilong Yang
Shilong Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10889606Abstract: A method for preparing a biflavone-iron complex, includes using the amentoflavone as the ligand and the ferric ion as the central ion, the amentoflavone-iron complex is obtained by reaction, and the structure of the complex is characterized by infrared spectroscopy, UV-vis absorption spectroscopy and high resolution mass spectrometry. Meanwhile, the antitumor and antioxidant activities of the amentoflavone-iron complex are studied in the present invention. MTT method shows that the amentoflavone-iron complex has a relatively good antitumor activity, and the antitumor activity thereof is stronger than that of the amentoflavone. Pyrogallol auto-oxidation method and ABTS method show that the antioxidative activity of the amentoflavone-iron complex is stronger than that of the amentoflavone itself.Type: GrantFiled: February 13, 2018Date of Patent: January 12, 2021Assignee: NANJING FORESTRY UNIVERSITYInventors: Li Xu, Fuliang Cao, Shilong Yang
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Patent number: 10815254Abstract: The present invention discloses a biflavone-zinc complex, a preparation method and application thereof. In the present invention, using the amentoflavone as the ligand and the zinc ion as the central ion, the amentoflavone-zinc complex is obtained by reaction, and the structure of the complex is characterized by infrared spectroscopy, UV-vis absorption spectroscopy and high resolution mass spectrometry. Meanwhile, the antitumor and antioxidant activities of the amentoflavone-zinc complex are studied in the present invention. MTT method shows that the amentoflavone-zinc complex has better antitumor activity, and the antitumor activity thereof is stronger than that of the amentoflavone. Pyrogallol auto-oxidation method and ABTS method show that the antioxidative activity of the amentoflavone-zinc complex is stronger than that of the amentoflavone itself.Type: GrantFiled: February 13, 2018Date of Patent: October 27, 2020Assignee: NANJING FORESTRY UNIVERSITYInventors: Fuliang Cao, Li Xu, Shilong Yang
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Patent number: 10815252Abstract: A biflavone-copper complex, a preparation method and application thereof are disclosed. The biflavone-copper complex has the following structural formula: wherein, X is NO3? or Cl?. A method of preparing the biflavone-copper complex includes the following steps: dissolving a copper salt in an alcohol and then adding into a biflavone alcoholic solution, controlling pH to 5-7; under heating and stirring, performing a reaction for 2-5 h to form a precipitate; filtering the precipitate, washing the precipitate with alcohol and water, recrystallizing the precipitate using dimethyl sulfoxide as a solvent, and drying the precipitate to obtain the biflavone-copper complex. The biflavone-copper complex is used for preparing an antitumor drug and/or an antioxidant drug.Type: GrantFiled: February 13, 2018Date of Patent: October 27, 2020Assignee: NANJING FORESTRY UNIVERSITYInventors: Li Xu, Shilong Yang, Zhong Li
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Patent number: 10808001Abstract: A method for preparing a biflavone-cobalt complex includes using the amentoflavone as the ligand and the cobalt ion as the central ion, the amentoflavone-cobalt complex is obtained by reaction, and the structure of the complex is characterized by infrared spectroscopy, UV-vis absorption spectroscopy and high resolution mass spectrometry. Meanwhile, the antitumor and antioxidant activities of the amentoflavone-cobalt complex are studied in the present invention. MTT method shows that the amentoflavone-cobalt complex has better antitumor activity, and the antitumor activity thereof is stronger than that of the amentoflavone. Pyrogallol auto-oxidation method, ABTS method and FRAP method show that the antioxidan activity of the amentoflavone-cobalt complex is stronger than that of the amentoflavone itself. The formation of the flavonoid-cobalt complex enhances the antitumor and anti-oxidation activities of the amentoflavone, and is expected to be used in the development of drugs.Type: GrantFiled: February 13, 2018Date of Patent: October 20, 2020Assignee: NANJING FORESTRY UNIVERSITYInventors: Guibin Wang, Li Xu, Shilong Yang, Fuliang Cao
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Publication number: 20200247825Abstract: The present invention discloses a biflavone-zinc complex, a preparation method and application thereof. In the present invention, using the amentoflavone as the ligand and the zinc ion as the central ion, the amentoflavone-zinc complex is obtained by reaction, and the structure of the complex is characterized by infrared spectroscopy, UV-vis absorption spectroscopy and high resolution mass spectrometry. Meanwhile, the antitumor and antioxidant activities of the amentoflavone-zinc complex are studied in the present invention. MTT method shows that the amentoflavone-zinc complex has better antitumor activity, and the antitumor activity thereof is stronger than that of the amentoflavone. Pyrogallol auto-oxidation method and ABTS method show that the antioxidative activity of the amentoflavone-zinc complex is stronger than that of the amentoflavone itself.Type: ApplicationFiled: February 13, 2018Publication date: August 6, 2020Applicant: NANJING FORESTRY UNIVERSITYInventors: Fuliang CAO, Li XU, Shilong YANG
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Publication number: 20200239506Abstract: A method for preparing a biflavone-iron complex, includes using the amentoflavone as the ligand and the ferric ion as the central ion, the amentoflavone-iron complex is obtained by reaction, and the structure of the complex is characterized by infrared spectroscopy, UV-vis absorption spectroscopy and high resolution mass spectrometry. Meanwhile, the antitumor and antioxidant activities of the amentoflavone-iron complex are studied in the present invention. MTT method shows that the amentoflavone-iron complex has a relatively good antitumor activity, and the antitumor activity thereof is stronger than that of the amentoflavone. Pyrogallol auto-oxidation method and ABTS method show that the antioxidative activity of the amentoflavone-iron complex is stronger than that of the amentoflavone itself.Type: ApplicationFiled: February 13, 2018Publication date: July 30, 2020Applicant: NANJING FORESTRY UNIVERSITYInventors: Li XU, Fuliang CAO, Shilong YANG
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Publication number: 20200239507Abstract: A method for preparing a biflavone-cobalt complex includes using the amentoflavone as the ligand and the cobalt ion as the central ion, the amentoflavone-cobalt complex is obtained by reaction, and the structure of the complex is characterized by infrared spectroscopy, UV-vis absorption spectroscopy and high resolution mass spectrometry. Meanwhile, the antitumor and antioxidant activities of the amentoflavone-coablt complex are studied in the present invention. MTT method shows that the amentoflavone-cobalt complex has better antitumor activity, and the antitumor activity thereof is stronger than that of the amentoflavone. Pyrogallol auto-oxidation method, ABTS method and FRAP method show that the antioxidan activity of the amentoflavone-cobalt complex is stronger than that of the amentoflavone itself. The formation of the flavonoid-cobalt complex enhances the antitumor and anti-oxidation activities of the amentoflavone, and is expected to be used in the development of drugs.Type: ApplicationFiled: February 13, 2018Publication date: July 30, 2020Applicant: NANJING FORESTRY UNIVERSITYInventors: Guibin WANG, Li XU, Shilong YANG, Fuliang CAO
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Publication number: 20200010483Abstract: A biflavone-copper complex, a preparation method and application thereof are disclosed. The biflavone-copper complex has the following structural formula: wherein, X is NO3? or Cl?. A method of preparing the biflavone-copper complex includes the following steps: dissolving a copper salt in an alcohol and then adding into a biflavone alcoholic solution, controlling pH to 5-7; under heating and stirring, performing a reaction for 2-5 h to form a precipitate; filtering the precipitate, washing the precipitate with alcohol and water, recrystallizing the precipitate using dimethyl sulfoxide as a solvent, and drying the precipitate to obtain the biflavone-copper complex. The biflavone-copper complex is used for preparing an antitumor drug and/or an antioxidant drug.Type: ApplicationFiled: February 13, 2018Publication date: January 9, 2020Applicant: NANJING FORESTRY UNIVERSITYInventors: Li XU, Shilong YANG, Zhong LI
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Patent number: 7664489Abstract: A method for a communication between two cellular phones is provided, in which the communication between the cellular phones includes an intercom communication and a telephone communication. The method includes steps of providing a telephone number of one cellular phone and an intercom number associated with the telephone number in the other cellular phone, dialing the telephone number of the one cellular phone by the other cellular phone to activate a calling to the intercom number associated with the telephone number, determining whether the cellular phones are within an intercom communication area, and performing the intercom communication therebetween while the cellular phones are within an intercom communication area, or performing the telephone communication therebetween while the cellular phones are without an intercom communication area.Type: GrantFiled: January 30, 2006Date of Patent: February 16, 2010Assignee: Inventec Appliances Corp.Inventors: Chengshing Lai, Shilong Yang
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Publication number: 20060172728Abstract: A method for a communication between two cellular phones is provided, in which the communication between the cellular phones includes an intercom communication and a telephone communication. The method includes steps of providing a telephone number of one cellular phone and an intercom number associated with the telephone number in the other cellular phone, dialing the telephone number of the one cellular phone by the other cellular phone to activate a calling to the intercom number associated with the telephone number, determining whether the cellular phones are within an intercom communication area, and performing the intercom communication therebetween while the cellular phones are within an intercom communication area, or performing the telephone communication therebetween while the cellular phones are without an intercom communication area.Type: ApplicationFiled: January 30, 2006Publication date: August 3, 2006Inventors: Chengshing Lai, Shilong Yang