Patents by Inventor Shimian Qu
Shimian Qu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10086073Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.Type: GrantFiled: April 8, 2016Date of Patent: October 2, 2018Assignee: WASHINGTON UNIVERSITYInventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
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Publication number: 20160206736Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.Type: ApplicationFiled: April 8, 2016Publication date: July 21, 2016Applicants: Vanderbilt University, Washington UniversityInventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
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Patent number: 9340581Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.Type: GrantFiled: June 18, 2014Date of Patent: May 17, 2016Assignee: WASHINGTON UNIVERSITYInventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
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Publication number: 20140369929Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.Type: ApplicationFiled: June 18, 2014Publication date: December 18, 2014Applicant: VANDERBILT UNIVERSITYInventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
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Patent number: 8765097Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.Type: GrantFiled: February 13, 2013Date of Patent: July 1, 2014Assignees: Washington University, Vanderbilt UniversityInventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
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Publication number: 20130251628Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.Type: ApplicationFiled: February 13, 2013Publication date: September 26, 2013Applicant: Vanderbilt UniversityInventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
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Patent number: 8388932Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.Type: GrantFiled: February 1, 2011Date of Patent: March 5, 2013Assignee: Vanderbilt UniversityInventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
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Publication number: 20110213293Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.Type: ApplicationFiled: February 1, 2011Publication date: September 1, 2011Applicant: VANDERBILT UNIVERSITYInventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
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Patent number: 7968675Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are therapeutic and diagnostic methods using targeting ligands that bind an irradiated tumor.Type: GrantFiled: April 29, 2008Date of Patent: June 28, 2011Assignee: Vanderbilt UniversityInventors: Dennis E. Hallahan, Shimian Qu
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Patent number: 7906102Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.Type: GrantFiled: July 15, 2005Date of Patent: March 15, 2011Assignee: Vanderbilt UniversityInventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
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Publication number: 20080206130Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are therapeutic and diagnostic methods using targeting ligands that bind an irradiated tumor.Type: ApplicationFiled: April 29, 2008Publication date: August 28, 2008Inventors: Dennis E. Hallahan, Shimian Qu
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Patent number: 7402392Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are therapeutic and diagnostic methods using targeting ligands that bind an irradiated tumor.Type: GrantFiled: September 27, 2002Date of Patent: July 22, 2008Assignee: Vanderbilt UniversityInventors: Dennis E. Hallahan, Shimian Qu
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Publication number: 20060104898Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.Type: ApplicationFiled: July 15, 2005Publication date: May 18, 2006Inventors: Dennis Hallahan, Shimian Qu, Zhaozhong Han
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Publication number: 20030130190Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are therapeutic and diagnostic methods using targeting ligands that bind an irradiated tumor.Type: ApplicationFiled: September 27, 2002Publication date: July 10, 2003Applicant: Vanderbilt UniversityInventors: Dennis E. Hallahan, Shimian Qu