Patents by Inventor Shimian Qu

Shimian Qu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10086073
    Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: October 2, 2018
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
  • Publication number: 20160206736
    Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.
    Type: Application
    Filed: April 8, 2016
    Publication date: July 21, 2016
    Applicants: Vanderbilt University, Washington University
    Inventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
  • Patent number: 9340581
    Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.
    Type: Grant
    Filed: June 18, 2014
    Date of Patent: May 17, 2016
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
  • Publication number: 20140369929
    Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.
    Type: Application
    Filed: June 18, 2014
    Publication date: December 18, 2014
    Applicant: VANDERBILT UNIVERSITY
    Inventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
  • Patent number: 8765097
    Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.
    Type: Grant
    Filed: February 13, 2013
    Date of Patent: July 1, 2014
    Assignees: Washington University, Vanderbilt University
    Inventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
  • Publication number: 20130251628
    Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.
    Type: Application
    Filed: February 13, 2013
    Publication date: September 26, 2013
    Applicant: Vanderbilt University
    Inventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
  • Patent number: 8388932
    Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.
    Type: Grant
    Filed: February 1, 2011
    Date of Patent: March 5, 2013
    Assignee: Vanderbilt University
    Inventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
  • Publication number: 20110213293
    Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.
    Type: Application
    Filed: February 1, 2011
    Publication date: September 1, 2011
    Applicant: VANDERBILT UNIVERSITY
    Inventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
  • Patent number: 7968675
    Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are therapeutic and diagnostic methods using targeting ligands that bind an irradiated tumor.
    Type: Grant
    Filed: April 29, 2008
    Date of Patent: June 28, 2011
    Assignee: Vanderbilt University
    Inventors: Dennis E. Hallahan, Shimian Qu
  • Patent number: 7906102
    Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.
    Type: Grant
    Filed: July 15, 2005
    Date of Patent: March 15, 2011
    Assignee: Vanderbilt University
    Inventors: Dennis E. Hallahan, Shimian Qu, Zhaozhong Han
  • Publication number: 20080206130
    Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are therapeutic and diagnostic methods using targeting ligands that bind an irradiated tumor.
    Type: Application
    Filed: April 29, 2008
    Publication date: August 28, 2008
    Inventors: Dennis E. Hallahan, Shimian Qu
  • Patent number: 7402392
    Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are therapeutic and diagnostic methods using targeting ligands that bind an irradiated tumor.
    Type: Grant
    Filed: September 27, 2002
    Date of Patent: July 22, 2008
    Assignee: Vanderbilt University
    Inventors: Dennis E. Hallahan, Shimian Qu
  • Publication number: 20060104898
    Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.
    Type: Application
    Filed: July 15, 2005
    Publication date: May 18, 2006
    Inventors: Dennis Hallahan, Shimian Qu, Zhaozhong Han
  • Publication number: 20030130190
    Abstract: A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are therapeutic and diagnostic methods using targeting ligands that bind an irradiated tumor.
    Type: Application
    Filed: September 27, 2002
    Publication date: July 10, 2003
    Applicant: Vanderbilt University
    Inventors: Dennis E. Hallahan, Shimian Qu