Patents by Inventor Shimiao Wang

Shimiao Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF
    Publication number: 20240109866
    Abstract: Described herein are compounds that are melanocortin subtype-2 receptor (MC2R) modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of MC2R activity.
    Type: Application
    Filed: June 1, 2023
    Publication date: April 4, 2024
    Inventors: Sangdon HAN, Yunfei ZHU, Sun Hee KIM, Jian ZHAO, Shimiao WANG
  • PARATHYROID HORMONE (PTH) RECEPTOR ANTAGONISTS AND USES THEREOF
    Publication number: 20230159532
    Abstract: Described herein are compounds that are parathyroid hormone (PTH) receptor modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of PTH receptor activity.
    Type: Application
    Filed: September 29, 2022
    Publication date: May 25, 2023
    Inventors: Joseph PONTILLO, Shimiao WANG, Yunfei ZHU
  • Somatostatin modulators and uses thereof
    Patent number: 11608335
    Abstract: Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: March 21, 2023
    Assignee: CRINETICS PHARMACEUTICALS, INC.
    Inventors: Jian Zhao, Shimiao Wang, Yunfei Zhu
  • Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof
    Patent number: 11566015
    Abstract: Described herein are compounds that are melanocortin subtype-2 receptor (MC2R) modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of MC2R activity.
    Type: Grant
    Filed: February 8, 2021
    Date of Patent: January 31, 2023
    Assignee: CRINETICS PHARMACEUTICALS, INC.
    Inventors: Sangdon Han, Yunfei Zhu, Sun Hee Kim, Jian Zhao, Shimiao Wang
  • SOMATOSTATIN MODULATORS AND USES THEREOF
    Publication number: 20220380337
    Abstract: Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
    Type: Application
    Filed: July 1, 2022
    Publication date: December 1, 2022
    Inventors: Jian ZHAO, Sangdon HAN, Sun Hee KIM, Shimiao WANG, Yunfei ZHU
  • Nonpeptide somatostatin type 5 receptor agonists and uses thereof
    Patent number: 11479540
    Abstract: Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: October 25, 2022
    Assignee: CRINETICS PHARMACEUTICALS, INC.
    Inventors: Jian Zhao, Yunfei Zhu, Shimiao Wang, Mi Chen, Joseph Pontillo
  • Somatostatin modulators and uses thereof
    Patent number: 11414397
    Abstract: Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: August 16, 2022
    Assignee: CRINETICS PHARMACEUTICALS, INC.
    Inventors: Jian Zhao, Sangdon Han, Sun Hee Kim, Shimiao Wang, Yunfei Zhu
  • NONPEPTIDE SOMATOSTATIN TYPE 5 RECEPTOR AGONISTS AND USES THEREOF
    Publication number: 20220144802
    Abstract: Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
    Type: Application
    Filed: January 21, 2022
    Publication date: May 12, 2022
    Inventors: Jian ZHAO, Yunfei ZHU, Shimiao WANG, Mi CHEN, Joseph PONTILLO
  • MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF
    Publication number: 20210238164
    Abstract: Described herein are compounds that are melanocortin subtype-2 receptor (MC2R) modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of MC2R activity.
    Type: Application
    Filed: February 8, 2021
    Publication date: August 5, 2021
    Inventors: Sangdon HAN, Yunfei ZHU, Sun Hee KIM, Jian ZHAO, Shimiao WANG
  • SOMATOSTATIN MODULATORS AND USES THEREOF
    Publication number: 20210171492
    Abstract: Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
    Type: Application
    Filed: October 26, 2020
    Publication date: June 10, 2021
    Inventors: Jian ZHAO, Sangdon HAN, Sun Hee KIM, Shimiao WANG, Yunfei ZHU
  • Somatostatin modulators and uses thereof
    Patent number: 11028068
    Abstract: Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: June 8, 2021
    Assignee: CRINETICS PHARMACEUTICALS, INC.
    Inventors: Jian Zhao, Yunfei Zhu, Shimiao Wang, Sangdon Han, Sun Hee Kim
  • PYRIDYL BENZOTHIOPHENES AS KINASE INHIBITORS
    Publication number: 20210115029
    Abstract: This invention is directed to compounds, which are useful as protein kinase (PK) inhibitors and can be used to treat such diseases as cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders, metabolic diseases inflammatory disorders and neurodegenerative disorders.
    Type: Application
    Filed: May 28, 2020
    Publication date: April 22, 2021
    Inventors: Sougato Boral, Thomas C. Malone, Shimiao Wang
  • Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof
    Patent number: 10981894
    Abstract: Described herein are compounds that are melanocortin subtype-2 receptor (MC2R) modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of MC2R activity.
    Type: Grant
    Filed: July 16, 2020
    Date of Patent: April 20, 2021
    Assignee: CRINETICS PHARMACEUTICALS, INC.
    Inventors: Sangdon Han, Yunfei Zhu, Sun Hee Kim, Jian Zhao, Shimiao Wang
  • NONPEPTIDE SOMATOSTATIN TYPE 5 RECEPTOR AGONISTS AND USES THEREOF
    Publication number: 20210047287
    Abstract: Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
    Type: Application
    Filed: August 10, 2020
    Publication date: February 18, 2021
    Inventors: Jian ZHAO, Yunfei ZHU, Shimiao WANG, Mi CHEN, Joseph PONTILLO
  • SOMATOSTATIN MODULATORS AND USES THEREOF
    Publication number: 20210040087
    Abstract: Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
    Type: Application
    Filed: February 11, 2019
    Publication date: February 11, 2021
    Inventors: Jian ZHAO, Shimiao WANG, Yunfei ZHU
  • MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF
    Publication number: 20210002254
    Abstract: Described herein are compounds that are melanocortin subtype-2 receptor (MC2R) modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of MC2R activity.
    Type: Application
    Filed: July 16, 2020
    Publication date: January 7, 2021
    Inventors: Sangdon HAN, Yunfei ZHU, Sun Hee KIM, Jian ZHAO, Shimiao WANG
  • Somatostatin modulators and uses thereof
    Patent number: 10875839
    Abstract: Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: December 29, 2020
    Assignee: CRINETICS PHARMACEUTICALS, INC.
    Inventors: Jian Zhao, Shimiao Wang, Yunfei Zhu
  • SOMATASTATIN MODULATORS AND USES THEREOF
    Publication number: 20200207737
    Abstract: Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
    Type: Application
    Filed: July 24, 2018
    Publication date: July 2, 2020
    Inventors: Jian ZHAO, Yunfei ZHU, Shimiao WANG, Sangdon HAN, Sun Hee KIM
  • SOMATOSTATIN MODULATORS AND USES THEREOF
    Publication number: 20200190053
    Abstract: Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
    Type: Application
    Filed: December 12, 2019
    Publication date: June 18, 2020
    Inventors: Jian ZHAO, Sangdon HAN, Sun Hee KIM, Shimiao WANG, Yunfei ZHU
  • Pyridyl benzothiophenes as kinase inhibitors
    Patent number: 10669265
    Abstract: This invention is directed to compounds, which are useful as protein kinase (PK) inhibitors and can be used to treat such diseases as cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders, metabolic diseases inflammatory disorders and neurodegenerative disorders.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: June 2, 2020
    Assignee: ALLERGAN, INC.
    Inventors: Sougato Boral, Thomas C. Malone, Shimiao Wang