Abstract: A system, a method, and a composition for targeted gene manipulation and use thereof are provided. The system specifically targets an RNA molecule encoding an ApoE4 protein, which may be used to treat diseases such as Alzheimer's disease.

Abstract: The present disclosure provides a touch screen sensor and a touch screen with the touch screen sensor. The touch screen sensor includes a plurality of grid cells, wherein the plurality of grid cells are connected to each other to form the touch screen sensor; and each grid cell includes a plurality of metal electrode wires arranged in an intersecting manner, the plurality of grid cells at least form a three-wire intersection mode at part of intersection points, and a plurality of identical grid cells are repeatedly connected or different grid cells are arranged in the intersecting manner to form a touch electrode. In some embodiments of the present disclosure, at least part of the intersection points of a four-wire intersection mode of the grid cells are adjusted and arranged to be intersection points of the three-wire intersection mode.

Abstract: The present disclosure provides a touch screen sensor and a touch screen with the touch screen sensor. The touch screen sensor includes a plurality of grid cells, wherein the plurality of grid cells are connected to each other to form the touch screen sensor; and each grid cell includes a plurality of metal electrode wires arranged in an intersecting manner, the plurality of grid cells at least form a three-wire intersection mode at part of intersection points, and a plurality of identical grid cells are repeatedly connected or different grid cells are arranged in the intersecting manner to form a touch electrode. In some embodiments of the present disclosure, at least part of the intersection points of a four-wire intersection mode of the grid cells are adjusted and arranged to be intersection points of the three-wire intersection mode.

Abstract: A coating composition including (a) a first polyester material having a number-average molecular weight (Mn) of 500 to 5,500 Daltons, and (b) a second polyester material having a number-average molecular weight (Mn) of 6,000 to 100,00 Daltons. The first polyester material may have a glass transition temperature (Tg) of from 40° C. to 120° C. The coating composition is useful for, among other things, coating food and/or beverage containers, such as an undercoat layer of a two layer coating system that includes an undercoat layer and an overcoat layer.

Abstract: A capacitive touch screen includes a substrate (01), a touch electrode layer (02), and a decorative layer (03). The substrate (01) has a first surface, the first surface includes a first region (011) and a second region (012), and the second region (012) is positioned on one side of the first region (011), the decorative layer (03) is formed on the second region (012). The touch electrode layer (02) is formed on the first region (011) of the first surface, and the touch electrode layer (02) extends above the decorative layer (03) on the second region (012), the touch electrode layer (02) includes a plurality of touch patterns, two adjacent touch patterns on the first region (011) are provided with a first gap (04) therebetween, two adjacent touch patterns on the second region (012) are provided with a second gap (05) therebetween, and a width of the second gap (05) is greater than a width of the first gap (04).

Abstract: A touch display device includes a display panel (101), a touch panel (103), a bonding member (104), and a bonding layer (102) bonding the touch panel (101) and the display panel (102) together. The touch panel (101) includes a first functional layer (1031), the first functional layer (1031) is positioned on a surface of the display panel (103) adjacent to the bonding layer (102), the first functional layer (1031) has a first side surface (103a). The bonding member (104) is positioned on a periphery of the bonding layer (102), wherein the bonding member (104) is at least bonded to a portion of the first side surface (103a).

Abstract: A coating composition comprising: (a) a first polyester material having a number-average molecular weight (Mn) of 500 to 5,500 Daltons, and (b) a second polyester material having a number-average molecular weight (Mn) of 6,000 to 100,000 Daltons. The coating composition is useful for, among other things, coating food and/or beverage containers.

Abstract: A touch display device includes a display panel (101), a touch panel (103), a bonding member (104), and a bonding layer (102) bonding the touch panel (101) and the display panel (102) together. The touch panel (101) includes a first functional layer (1031), the first functional layer (1031) is positioned on a surface of the display panel (103) adjacent to the bonding layer (102), the first functional layer (1031) has a first side surface (103a). The bonding member (104) is positioned on a periphery of the bonding layer (102), wherein the bonding member (104) is at least bonded to a portion of the first side surface (103a).

Abstract: A capacitive touch screen includes a substrate (01), a touch electrode layer (02), and a decorative layer (03). The substrate (01) has a first surface, the first surface includes a first region (011) and a second region (012), and the second region (012) is positioned on one side of the first region (011), the decorative layer (03) is formed on the second region (012). The touch electrode layer (02) is formed on the first region (011) of the first surface, and the touch electrode layer (02) extends above the decorative layer (03) on the second region (012), the touch electrode layer (02) includes a plurality of touch patterns, two adjacent touch patterns on the first region (011) are provided with a first gap (04) therebetween, two adjacent touch patterns on the second region (012) are provided with a second gap (05) therebetween, and a width of the second gap (05) is greater than a width of the first gap (04).