Patents by Inventor Shiming LV

Shiming LV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CTLA-4 SMALL MOLECULE DEGRADATION AGENT AND APPLICATION THEREOF
    Publication number: 20240199654
    Abstract: A CTLA-4 small molecule degradation agent and an application thereof. The CTLA-4 small molecule degradation agent comprises a compound having the structure represented by formula I or a pharmaceutically acceptable salt, an ester, a deuterated product, an isomer, a solvate, a prodrug, or an isotopic label thereof: a new class of small molecule compounds having high degradation activity on CTLA-4. The compounds show a good degradation activity on CTLA-4 at the nanomolar (nM) level in in vitro studies.
    Type: Application
    Filed: March 17, 2022
    Publication date: June 20, 2024
    Applicant: SUZHOU GUOKUANG PHARMTECH. CO., LTD.
    Inventors: Desheng MEI, Baokun HE, Shiming LV, Gaorui SUN, Kui WANG, Cheng XIAO, Min LIANG, Xin LING, Shuaishuai LIU