Patents by Inventor Shimon Amselem

Shimon Amselem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiol and disulfide-containing agents for increasing meibomian gland lipid secretion
    Patent number: 10688122
    Abstract: Described herein are compositions and methods for the increasing the quantity of lipids secreted from meibomian glands. Such compositions and methods are useful for the treatment of meibomian gland dysfunction and disorders resulting therefrom.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: June 23, 2020
    Assignee: AZURA OPHTHALMICS LTD.
    Inventors: Shimon Amselem, Yair Alster, Doron Friedman, Omer Rafaeli
  • THIOL AND DISULFIDE-CONTAINING AGENTS FOR INCREASING MEIBOMIAN GLAND LIPID SECRETION
    Publication number: 20200179440
    Abstract: Described herein are compositions and methods for the increasing the quantity of lipids secreted from meibomian glands. Such compositions and methods are useful for the treatment of meibomian gland dysfunction and disorders resulting therefrom.
    Type: Application
    Filed: February 19, 2020
    Publication date: June 11, 2020
    Inventors: Shimon AMSELEM, Yair ALSTER, Doron FRIEDMAN, Omer RAFAELI
  • Compositions and methods for the treatment of meibomian gland dysfunction
    Patent number: 10588915
    Abstract: Described herein are compositions and methods for the treatment of meibomian gland dysfunction. Said compositions and methods comprise keratolytic agents, such as salicylic acid, selenium disulfide, or the like. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from meibomian gland dysfunction.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: March 17, 2020
    Assignee: AZURA OPHTHALMICS LTD.
    Inventors: Yair Alster, Omer Rafaeli, K. Angela MacFarlane, Cary Reich, Shimon Amselem, Doron Friedman
  • AGENTS FOR INCREASING MEIBOMIAN GLAND LIPID SECRETION
    Publication number: 20200030268
    Abstract: Described herein are compositions and methods for the increasing the quantity of lipids secreted from meibomian glands. Such compositions and methods are useful for the treatment of meibomian gland dysfunction and disorders resulting therefrom.
    Type: Application
    Filed: March 28, 2018
    Publication date: January 30, 2020
    Inventors: Shimon AMSELEM, Yair ALSTER, Doron FRIEDMAN, Omer RAFAELI
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF MEIBOMIAN GLAND DYSFUNCTION
    Publication number: 20190388440
    Abstract: Described herein are compositions and methods for the treatment of meibomian gland dysfunction. Said compositions and methods comprise keratolytic agents, such as salicylic acid, selenium disulfide, or the like. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from meibomian gland dysfunction.
    Type: Application
    Filed: September 5, 2019
    Publication date: December 26, 2019
    Inventors: Yair ALSTER, Omer RAFAELI, K. Angela MACFARLANE, Cary REICH, Shimon AMSELEM, Doron FRIEDMAN
  • COMPOSTIONS OF POLYMERIC MYRCENE
    Publication number: 20190255132
    Abstract: Compositions and formulations comprising polymeric myrcene. More particularly, the invention relates to compositions comprising an isolated fraction of polymeric myrcene in a hydrophobic carrier and formulations which maintain the biological activity of the active polymer.
    Type: Application
    Filed: April 23, 2019
    Publication date: August 22, 2019
    Applicant: REGENERA PHARMA LTD.
    Inventors: Zadik HAZAN, Shimon AMSELEM
  • Compositions of polymeric myrcene
    Patent number: 10307449
    Abstract: Compositions and formulations comprising polymeric myrcene. More particularly, the invention relates to compositions comprising an isolated fraction of polymeric myrcene in a hydrophobic carrier and formulations which maintain the biological activity of the active polymer.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: June 4, 2019
    Assignee: REGENERA PHARMA LTD.
    Inventors: Zadik Hazan, Shimon Amselem
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF MEIBOMIAN GLAND DYSFUNCTION
    Publication number: 20190125766
    Abstract: Described herein are compositions and methods for the treatment of meibomian gland dysfunction. Said compositions and methods comprise keratolytic agents, such as salicylic acid, selenium disulfide, or the like. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from meibomian gland dysfunction.
    Type: Application
    Filed: June 26, 2018
    Publication date: May 2, 2019
    Inventors: Yair ALSTER, Omer RAFAELI, K. Angela MACFARLANE, Cary REICH, Shimon AMSELEM, Doron FRIEDMAN
  • Depot formulations of a local anesthetic and methods for preparation thereof
    Patent number: 10206876
    Abstract: The invention provides extended release pro-liposomal, non-aqueous, pharmaceutical formulations of a local anesthetic in the form of a clear oily solution and methods for making same. The formulations can be administered by infiltration into an incision, or by injection.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: February 19, 2019
    Assignee: PAINREFORM LTD.
    Inventors: Shimon Amselem, Michael Naveh
  • Compositions and methods for the treatment of meibomian gland dysfunction
    Patent number: 10034887
    Abstract: Described herein are compositions and methods for the treatment of meibomian gland dysfunction. Said compositions and methods comprise keratolytic agents, such as salicylic acid, selenium disulfide, or the like. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from meibomian gland dysfunction.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: July 31, 2018
    Assignee: M.G. THERAPEUTICS, LTD.
    Inventors: Yair Alster, Omer Rafaeli, K. Angela MacFarlane, Cary Reich, Shimon Amselem, Doron Friedman
  • DEPOT FORMULATIONS OF A LOCAL ANESTHETIC AND METHODS FOR PREPARATION THEREOF
    Publication number: 20180049985
    Abstract: The invention provides extended release pro-liposomal, non-aqueous, pharmaceutical formulations of a local anesthetic in the form of a clear oily solution and methods for making same. The formulations can be administered by infiltration into an incision, or by injection.
    Type: Application
    Filed: May 2, 2017
    Publication date: February 22, 2018
    Applicant: PAINREFORM LTD.
    Inventors: Shimon AMSELEM, Michael NAVEH
  • Depot formulations of a hydrophobic active ingredient and methods for preparation thereof
    Patent number: 9849088
    Abstract: The invention provides extended release pro-liposomal, non-aqueous, pharmaceutical formulations of a hydrophobic active pharmaceutical ingredient (API) of low water solubility but readily dissolved in alcohols and methods for making same. The formulations can be administered by infiltration into an incision, or by injection.
    Type: Grant
    Filed: May 9, 2013
    Date of Patent: December 26, 2017
    Assignee: Painreform Ltd.
    Inventors: Shimon Amselem, Michael Naveh
  • Method for decreasing symptoms of alcohol consumption
    Patent number: 9808446
    Abstract: The present invention relates to methods and compositions of metadoxine and physiologically compatible active derivatives thereof, and their use for decreasing symptoms of alcohol consumption as well as in the prevention of alcohol consumption related symptoms in subjects in need thereof.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: November 7, 2017
    Assignee: Alcobra Ltd.
    Inventors: Gur Megiddo, Dalia Megiddo, Rina Yamin, Yaron Ilan, Shimon Amselem
  • COMPOSITIONS OF POLYMERIC MYRCENE
    Publication number: 20170252387
    Abstract: Compositions and formulations comprising polymeric myrcene. More particularly, the invention relates to compositions comprising an isolated fraction of polymeric myrcene in a hydrophobic carrier and formulations which maintain the biological activity of the active polymer.
    Type: Application
    Filed: April 13, 2017
    Publication date: September 7, 2017
    Applicant: REGENERA PHARMA LTD.
    Inventors: Zadik HAZAN, Shimon AMSELEM
  • Depot formulations of a local anesthetic and methods for preparation thereof
    Patent number: 9668974
    Abstract: The invention provides extended release pro-liposomal, non-aqueous, pharmaceutical formulations of a local anesthetic in the form of a clear oily solution and methods for making same. The formulations can be administered by infiltration into an incision, or by injection.
    Type: Grant
    Filed: May 9, 2013
    Date of Patent: June 6, 2017
    Assignee: PAINREFORM LTD.
    Inventors: Shimon Amselem, Michael Naveh
  • Compositions of polymeric myrcene
    Patent number: 9655938
    Abstract: The invention relates to compositions and formulations comprising polymeric myrcene. More particularly, the invention relates to compositions comprising an isolated fraction of polymeric myrcene in a hydrophobic carrier and formulations which maintain the biological activity of the active polymer.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: May 23, 2017
    Assignee: Regenera Pharma LTD.
    Inventors: Zadik Hazan, Shimon Amselem
  • Thiol and Disulfide-Containing Agents for Increasing Meibomian Gland Lipid Secretion
    Publication number: 20170087179
    Abstract: Described herein are compositions and methods for the increasing the quantity of lipids secreted from meibomian glands. Such compositions and methods are useful for the treatment of meibomian gland dysfunction and disorders resulting therefrom.
    Type: Application
    Filed: September 28, 2016
    Publication date: March 30, 2017
    Inventors: Shimon AMSELEM, Yair ALSTER, Doron FRIEDMAN, Omer RAFAELI
  • Flumazenil complexes, compositions comprising same and uses thereof
    Patent number: 9585893
    Abstract: Soluble complexes of flumazenil, methods for the preparation thereof, pharmaceutical compositions including same and use of the compositions for alleviating or counteracting the various types of hypersomnia, drowsiness, residual effects associated with the administration of sleep/hypnotic drugs, alcohol intoxication or hepatic encephalopathy.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: March 7, 2017
    Assignee: COERULEUS LTD.
    Inventor: Shimon Amselem
  • Compositions and Methods for the Treatment of Meibomian Gland Dysfunction
    Publication number: 20170035785
    Abstract: Described herein are compositions and methods for the treatment of meibomian gland dysfunction. Said compositions and methods comprise keratolytic agents, such as salicylic acid, selenium disulfide, or the like. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from meibomian gland dysfunction.
    Type: Application
    Filed: September 19, 2016
    Publication date: February 9, 2017
    Inventors: Yair ALSTER, Omer RAFAELI, K. Angela MACFARLANE, Cary REICH, Shimon AMSELEM, Doron FRIEDMAN
  • Compositions and methods for the treatment of meibomian gland dysfunction
    Patent number: 9463201
    Abstract: Described herein are compositions and methods for the treatment of meibomian gland dysfunction. Said compositions and methods comprise keratolytic agents, such as salicylic acid, selenium disulfide, or the like. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from meibomian gland dysfunction.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: October 11, 2016
    Assignee: M.G. THERAPEUTICS LTD
    Inventors: Yair Alster, Omer Rafaeli, K. Angela Macfarlane, Cary Reich, Shimon Amselem, Doron Friedman