Patents by Inventor Shimon Ben Shabat

Shimon Ben Shabat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted cyclohexylidene-ethylidene-octahydro-indene compounds
    Patent number: 8716334
    Abstract: Novel substituted cyclohexylidene-ethylidene-octahydro-indene compounds and compositions comprising the same are described. The compounds exhibit profound anti-proliferative effects, in comparison to other compounds known for their anti-cancer and anti-hyperproliferative ability. Methods of use of such compounds and compositions are described for treating a variety of cancers, inflammatory and other hyperproliferative diseases and disorders.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: May 6, 2014
    Assignee: Ben Gurion University of the Negev Research and Development Authority
    Inventors: Shimon Ben Shabat, Amnou Sintov
  • Endocannabinoids for Enhancing Growth and Development in Infants
    Publication number: 20110172305
    Abstract: The present invention relates to a method for promoting infant feeding, growth or development comprising administering to an infant a formula or a pharmaceutical composition comprising an endocannabinoid in an amount sufficient to promote feeding, growth or development. The present invention also relates to an infant formula comprising an enhanced amount of an endocannabinoid. The infant formula of the invention may be in a powder form or in a liquid form. The infant formula or the pharmaceutical composition may further comprise an endocannabinoid-promoting compound.
    Type: Application
    Filed: October 2, 2008
    Publication date: July 14, 2011
    Inventors: Ester Fride, Ayala Polak-moshe, David Branski, Shimon Ben-Shabat
  • SUBSTITUTED CYCLOHEXYLIDENE-ETHYLIDENE-OCTAHYDRO-INDENE COMPOUNDS
    Publication number: 20110098350
    Abstract: Novel substituted cyclohexylidene-ethylidene-octahydro-indene compounds and compositions comprising the same are described. The compounds exhibit profound anti-proliferative effects, in comparison to other compounds known for their anti-cancer and anti-hyperproliferative ability. Methods of use of such compounds and compositions are described for treating a variety of cancers, inflammatory and other hyperproliferative diseases and disorders.
    Type: Application
    Filed: June 16, 2009
    Publication date: April 28, 2011
    Inventors: Shimon Ben Shabat, Amnou Sintov
  • Synthetic endogenous cannabinoids analogues and uses thereof
    Patent number: 6531636
    Abstract: The present invention relates to a compound of the general formula (I) which is a non-hydrolysable analogue of endogenous cannabinoids, which are found to be more potent therapeutic agents as they are more stable, for example, to hydrolytic cleavage in the gastrointestinal tract. The cannabinoid analogues of the invention have a therapeutic value. Therefore, pharmaceutical compositions comprising as active ingredient a therapeutically effective amount of at least one compound of the invention may be prepared. Such compositions may be used as anti-inflammatory, anti-asthmatic, analgetic, hypotensive, antiemetic or anti-spasmodic compositions, and as compositions for treating and/or preventing glaucoma or migraine, or as compositions for relieving symptoms of multiple sclerosis and mood stimulating compositions.
    Type: Grant
    Filed: October 3, 2000
    Date of Patent: March 11, 2003
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Raphael Mechoulam, Esther Fride, Shimon Ben Shabat, Tzviel Sheskin, Aviva Breuer