Patents by Inventor Shin Aizawa

Shin Aizawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11173158
    Abstract: Disclosed is a means for improving the symptoms of a cerebral dysfunction. The present inventors made a new discovery that the activity of brain aromatic monoamines increases when sepiapterin is administered peripherally. Disclosed, therefore, is a medicinal agent, which contains at least sepiapterin or a salt thereof, for preventing or improving cerebral dysfunction. Also disclosed is a beverage/food, which contains at least sepiapterin or a salt thereof, for preventing or improving cerebral dysfunction. Unlike tetrahydrobiopterin and the like, sepiapterin can control reductions in the brain neuron levels of brain aromatic monoamines (serotonin, dopamine, noradrenaline, and the like) and increase the activity thereof even when administered peripherally.
    Type: Grant
    Filed: June 18, 2019
    Date of Patent: November 16, 2021
    Assignees: PTC Therapeutics MP, Inc., Shiratori Pharmaceuticals Co., Ltd.
    Inventors: Hiroyuki Hasegawa, Shin Aizawa
  • Publication number: 20200009145
    Abstract: Disclosed is a means for improving the symptoms of a cerebral dysfunction. The present inventors made a new discovery that the activity of brain aromatic monoamines increases when sepiapterin is administered peripherally. Disclosed, therefore, is a medicinal agent, which contains at least sepiapterin or a salt thereof, for preventing or improving cerebral dysfunction. Also disclosed is a beverage/food, which contains at least sepiapterin or a salt thereof, for preventing or improving cerebral dysfunction. Unlike tetrahydrobiopterin and the like, sepiapterin can control reductions in the brain neuron levels of brain aromatic monoamines (serotonin, dopamine, noradrenaline, and the like) and increase the activity thereof even when administered peripherally.
    Type: Application
    Filed: June 18, 2019
    Publication date: January 9, 2020
    Inventors: Hiroyuki HASEGAWA, Shin AIZAWA
  • Publication number: 20130197000
    Abstract: [Problem] To provide means for improving symptoms of cerebral dysfunction. [Solution Means] The inventor has newly found that peripheral administration of sepiapterin increases the bioavailability of aromatic monoamines in the brain. Accordingly, provided are a drug for preventing or improving cerebral dysfunction, which contains at least one of sepiapterin and its salt and also provided is a food and or drink for preventing or improving cerebral dysfunction, which contains at least one of sepiapterin and its salt. Unlike tetrahydrobiopterin, etc., sepiapterin is able to repress the lowering level of aromatic monoamines (such as serotonin, dopamine and noradrenaline) in neurons in the brain and also increase the bioavailability.
    Type: Application
    Filed: April 22, 2011
    Publication date: August 1, 2013
    Applicant: NIHON UNIVERSITY
    Inventors: Hiroyuki Hasegawa, Shin Aizawa
  • Publication number: 20060211764
    Abstract: It is determined whether phase noise and parasitic oscillation take place on the basis of a carrier-to-noise (C/N) ratio calculated with amplitudes in an amplitude direction of signal points of a reception signal and a C/N ratio calculated with amplitudes in a phase direction of the signal points of the reception signal. Further, when it has been determined that phase noise and parasitic oscillation take place, an alarm is displayed on a screen. When it has been determined that phase noise and parasitic oscillation take place, the phase of a demodulation circuit is compensated based on the detected phase noise.
    Type: Application
    Filed: October 31, 2003
    Publication date: September 21, 2006
    Inventors: Yoichiro Nagasu, Shin Aizawa, Toshihisa Hoshiai, Tadatomo Nagao, Shouichi Nonaka