Patents by Inventor Shin-ichi Hirano
Shin-ichi Hirano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230158267Abstract: Described is a composition for ameliorating symptoms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and/or fibromyalgia (FM) that has few side effects and can be easily produced. Specifically, described is a composition for ameliorating at least one symptom of fatigue, headache, body pain, impaired thinking, impaired concentration, and/or impaired activity level associated with these symptoms caused by ME/CFS and/or FM in a patient, including a hydrogen gas-containing gas as an active ingredient. Also, described herein is a method for ameliorating symptoms such as fatigue, headache, body pain, impaired thinking, impaired concentration, and/or impaired activity levels associated with these symptoms caused by ME/CFS and/or FM in a patient with ME/CFS and/or FM, including administering the composition to the patient.Type: ApplicationFiled: September 8, 2022Publication date: May 25, 2023Applicant: MiZ Company LimitedInventors: Fumitake SATOH, Yoshiyasu TAKEFUJI, Takashi YAMAMURA, Bunpei SATO, Shin-ichi HIRANO, Yusuke ICHIAKWA
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Patent number: 6884364Abstract: A lead-free piezoelectric ceramic composition wherein a suitable amount of Cu is contained in a perovskite compound of a non-stoichiometric composition represented by a formula (KxA1-x)y(Nb1-zBz)O3, wherein “A” represents at least one of Na and Bi, while “B” represents at least one of Ta and Ti, and wherein 0<x?1, 0<y<1, and 0?z?1, so that by-products such as KaCubNbcOd and KaCubTacOd are produced as a result of reaction of (Nb1-zBz) with Cu in the process of calcination of a starting material, and the by-products restrict melting and abnormal grain growth of (KxNa1-x)(Nb1-zTaz) O3 during firing of a calcined body, thereby improving sinterability of the fired body, while restricting volatilization of alkali components and melting of KNbO3, thereby increasing the density and improving the piezoelectric properties of the fired body.Type: GrantFiled: September 23, 2003Date of Patent: April 26, 2005Assignees: Noritake Co., Limited, Nagoya Industrial Science Research InstituteInventors: Fuyutoshi Sato, Shin-ichi Hirano, Masato Matsubara, Wataru Sakamoto, Toshinobu Yogo, Koichi Kikuta
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Publication number: 20040224835Abstract: A ceramic carrier comprising a substrate ceramic containing Mg, Al, Si and O as constituent elements and containing, as the second component, an element other than said constituent elements. The support contains many microvoids capable of absorbing thermal expansion, the porosity is larger than 28%, and the thermal expansion coefficient is smaller than 2.3×10−6/° C. The second component enables the direct loading of a catalytic component.Type: ApplicationFiled: April 23, 2004Publication date: November 11, 2004Applicant: Denso CorporationInventors: Tomomi Hase, Kazuhiko Koike, Shin-ichi Hirano
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Publication number: 20040127344Abstract: A lead-free piezoelectric ceramic composition wherein a suitable amount of Cu is contained in a perovskite compound of a non-stoichiometric composition represented by a formula (KxA1−x)y(Nb1−zBz)O3, wherein “A” represents at least one of Na and Bi, while “B” represents at least one of Ta and Ti, and wherein 0<x≦1, 0<y<1, and 0≦z≦1, so that by-products such as KaCubNbcOd and KaCubTacOd are produced as a result of reaction of (Nb1−zBz) with Cu in the process of calcination of a starting material, and the by-products restrict melting and abnormal grain growth of (KxNa1-x)(Nb1−zTaz) O3 during firing of a calcined body, thereby improving sinterability of the fired body, while restricting volatilization of alkali components and melting of KNbO3, thereby increasing the density and improving the piezoelectric properties of the fired body.Type: ApplicationFiled: September 23, 2003Publication date: July 1, 2004Applicants: NORITAKE CO., LIMITED, NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTEInventors: Fuyutoshi Sato, Shin-ichi Hirano, Masato Matsubara, Wataru Sakamoto, Toshinobu Yogo, Koichi Kikuta
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Patent number: 6566394Abstract: Salicylamide derivatives represented by formulae (1a) and (1b); intermediates in the production thereof; a process for producing the same; and drugs containing the same as the active ingredient. The salicylamide derivatives represented by formulae (1a) and (1b) are useful as anti-inflammatory agents and immunosuppressive agents which exert an effect of inhibiting the activation of NF-&kgr;B with little side effects.Type: GrantFiled: May 30, 2002Date of Patent: May 20, 2003Assignees: Mercian Corporation, Zaidan Hojin Biseibutsu Kagaku Kenkyu KaiInventors: Tomio Takeuchi, Kazuo Umezawa, Sakino To-E, Naoki Matsumoto, Tsutomu Sawa, Takeo Yoshioka, Naoki Agata, Shin-ichi Hirano, Kunio Isshiki
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Patent number: 6269328Abstract: A testing integrated circuit device comprises a plurality of external terminals for being connected to a circuit board, a plurality of internal terminals provided corresponding to the external terminals each of which is provided with a plurality of connection terminals including a signal terminal, and a plurality of signal terminal setting. corresponding to the internal terminals for setting characteristics of the signal terminals. The connection terminals are provided so that a desired one of the connection terminals in the internal terminal can be connected to the corresponding external terminal.Type: GrantFiled: May 22, 1998Date of Patent: July 31, 2001Assignee: NEC CorporationInventor: Shin-ichi Hirano
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Patent number: 6027796Abstract: The present invention provides a ceramic film with a variety of structures having one-dimensional through channels which can be utilized favorably in the separation of molecules or microparticles or as a support film for a catalyst with a large surface area or for a catalyst of high activity, and also provides a method for manufacturing this film efficiently and with good reproducibility, and the present invention relates to a ceramic film having one-dimensional through channels, which is a porous ceramic film having nanometer-size pores that go through one-dimensionally from one surface of the film to the other surface, characterized in that the porous ceramic film is formed on a substrate of glass, ceramic, or a heat-resistant metal; and relates to a method for manufacturing the above-mentioned ceramic film.Type: GrantFiled: December 18, 1997Date of Patent: February 22, 2000Assignees: Japan as represented by Director General of Agency of Industrial Science and Technology, Fine Ceramics Research AssociationInventors: Shinji Kondoh, Shin-ichi Hirano, Koichi Kikuta
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Patent number: 6020363Abstract: Compounds of the formula (I) ##STR1## wherein R is a hydrogen atom or a C.sub.1-6 alkyl group and n is an integer of 0 or 1, and pharmaceutical preparations thereof are provided. These pharmaceutical preparations are useful for the prevention or treatment of diseases associated with an abnormality in immunological regulatory function or vascularization.Type: GrantFiled: December 17, 1998Date of Patent: February 1, 2000Assignees: Mercian Corporation, Zaidan Hojin Biseibutsu Kagaku Kenkyu KaiInventors: Shin-ichi Hirano, Toshiyuki Mase, Naoki Agata, Hiroshi Iguchi, Naoki Matsumoto, Takeo Yoshioka, Hiroshi Tone, Hiroyuki Kumagai, Masaaki Ishizuki, Tomio Takeuchi
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Patent number: 5440522Abstract: A memory system comprises a plurality of memory groups, a dynamic data line provided for each of the memory groups, a memory controller, a dynamic data line division circuit, and a data transfer controller. The dynamic data line division circuit performs connection and disconnection between the dynamic data lines of two adjacent memory groups. Monitoring the data input/output control of the memory controller, the data transfer controller switches the dynamic data line division circuit to a connection mode only when data transfer occurs between the two adjacent memory groups.Type: GrantFiled: December 6, 1994Date of Patent: August 8, 1995Assignee: NEC CorporationInventor: Shin-Ichi Hirano
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Patent number: 5275843Abstract: The invention provides a method of preparing .beta.-BaB.sub.2 O.sub.4 thin film. The beta barium boron thin film obtained does not contain impurities but has homogeneous structure, thus being applicable to various industrial fields including integrated circuits. The method of the invention includes the steps of melting and mixing boron alkoxide and metal barium or barium alkoxide in the presence of a solvent to prepare a homogeneous solution, covering a substrate with a thin film of the homogeneous solution or concentrated homogeneous solution, and firing the thin film in an atmosphere containing oxygen in a temperature range higher than 400.degree. C. and lower than 900.degree. C.Type: GrantFiled: May 20, 1992Date of Patent: January 4, 1994Assignee: NGK Spark Plug Co., Ltd.Inventor: Shin-ichi Hirano
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Patent number: 5223519Abstract: 4-Hydroxypyridine derivative represented by the following formula ##STR1## wherein R represents a methyl group or an isopropyl group, and the method for preparing the derivative comprising the step of cultivating a strain belonging to Streptomyces karnatakensis are disclosed. Also disclosed are the pharmaceutical composition comprising the same and a method for treating circulatory diseases comprising the step of administering said compound to a patient.Type: GrantFiled: December 13, 1991Date of Patent: June 29, 1993Assignee: Mercian CorporationInventors: Shin-ichi Hirano, Yoshio Watanabe, Kaichiro Kominato, Naoki Agata, Yutaka Hara, Norio Shibamoto, Takeo Yoshioka, Tomoyuki Kioka, Hiroshi Iguchi, Masataka Shirai, Hiroshi Tone, Rokuro Okamoto
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Patent number: 5211637Abstract: A device for connecting a catheter to an injection tube, which is provided with an elastic tube into which an open end of the tubular catheter having electrodes disposed at the closed end thereof and also having conductive wires connected to said electrodes and taken out at the open end thereof and an open end of the injection tube having a mechanism for fluid injection at the other end thereof are inserted so that both open ends are connected end-to-end and the conductive wires are taken out through a gap between the elastic tube and the injection tube; and a sealing agent to cover respective surfaces of the catheter, injection tube, and elastic tube which surfaces are coated with an adhesive. The catheter, injection tube, and elastic tube, when coated with an adhesive of high viscosity, are compatible with the hard sealing agent lying thereabove.Type: GrantFiled: December 6, 1991Date of Patent: May 18, 1993Assignees: Kabushiki-Kaisha Tokai-Rika-Denki-Seisakusho, Dow Corning Kabushiki-KaishaInventors: Yasuhiro Goto, Shin-ichi Hirano, Kiyoshi Asai
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Patent number: 5183883Abstract: Adriamycin derivatives represented by formula (I) ##STR1## wherein R denotes a divalent hydrocarbon group,CD denotes a cyclodextrin residue,m is 1 to 8, andn is 0 to 8.The compounds exhibit excellent anti-cancer activity over a wide administration range, have low toxicity and sustained release, and maintain activity for a long period of time; thus, they are quite useful as an anti-cancer agent.Type: GrantFiled: September 27, 1991Date of Patent: February 2, 1993Assignee: Mercian CorporationInventors: Hiroshi Tanaka, Kaichiro Kominato, Takeo Yoshioka, Hiroshi Iguchi, Shin-ichi Hirano, Yasuo Okajima, Reijko Yamamoto, Masataka Shirai, Hiroshi Nishida, Hiroshi Tone, Rokuro Okamoto
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Patent number: 5026684Abstract: A method is disclosed for preparation of superconductive substances, and in particular, those comprising a rar earth element, barium (Ba), copper (Cu) and oxygen, having a composition represented by the general formula: LnBa.sub.2 Cu.sub.3 O.sub.7-.delta. in which Ln represents a rare earth element and .delta. has a value of about 0 to 0.5. The method includes forming a solution containing an organic compound of a rear earth element, an organic barium compound and an organic copper compound in an organic solvent, homogenizing the resulting solution, stripping the organic solvent from the homogenized solution by evaporation to give a precipitate and pyrolyzing the precipitate to obtain the superconductive substance. The precipitate may also be formed as fibers or films prior to pyrolysis.Type: GrantFiled: April 12, 1989Date of Patent: June 25, 1991Assignees: Dow Corning Corporation, Shin-Ichi HiranoInventors: Ronald H. Baney, Shin-ichi Hirano
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Patent number: 4762729Abstract: There are disclosed a cubic boron nitride coated material including a substrate and an outer layer composed principally of cubic boron nitride and formed on a surface of the substrate, comprising an intermediate layer fored of at least one intermediate layer and interposed between the substrate and outer layer, the intermediate between the substrate and outer layer, the intermediate layer or the outermost one of intermediate layers being formed of a layer of at least one nitrogen-containing compound selected from the nitrides and nitroxides of Al, Ga, In and Tl and mutual solid solutions thereof, and a producing method of the same which comprises: providing, on the surface of the substrate, an intermediate layer formed of at least one intermediate layer, the intermediate layer or the outermost one of intermediate layers being formed of a layer of at least one nitrogen-containing compound selected from the group consisting of nitrides and nitroxides of Al, Ga, In and Tl and mutual solid solutions thereof; andType: GrantFiled: November 30, 1987Date of Patent: August 9, 1988Assignee: Toshiba Tungaloy Co., Ltd.Inventors: Shin-ichi Hirano, Susumu Yamaya
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Patent number: 4731303Abstract: A cubic boron nitride coated material comprises a substrate, an outer layer consisting essentially of cubic boron nitride and formed on a surface of the substrate, and at least one intermediate layer interposed between the substrate and outer layer, the intermediate layer comprising at least one nitrogen-containing compound selected from the nitrides and nitroxides of Al, Ga, In and Tl and mutual solid solutions thereof. Such a coated material can be produced by a method that comprises:providing, on the surface of a substrate, at least one intermediate layer comprised of at least one nitrogen-containing compound selected from the group consisting of nitrides and nitroxides of Al, Ga, In and Tl and mutual solid solutions thereof; andcausing the outer cubic boron nitride layer to undergo oriented growth on a face of the layer of the at least one nitrogen-containing compound, the face being densely packed with nitrogen atoms.Type: GrantFiled: July 16, 1986Date of Patent: March 15, 1988Assignee: Toshiba Tungaloy Co., Ltd.Inventors: Shin-ichi Hirano, Susumu Yamaya
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Patent number: 4590034Abstract: Disclosed is a method for preparing a sintered body containing cubic boron nitride which comprise the steps ofcontacting a starting material containing boron nitride and/or a starting material containing at least one selected from the group consisting of metals of groups IVa, Va and VIa of the periodic table, silicon, aluminum, iron group metals and compounds of the aforesaid metals with at least one selected from the group consisting of borazine, a borazine derivative and a compound composed of boron, nitrogen and hydrogen as will release hydrogen by a thermal decomposition under pressure to form boron nitride; andsintering the material under conditions of a predetermined pressure and temperature under which cubic boron nitride is kept stable. Also disclosed is a method for preparing cubic boron nitride which comprises, in addition to the above steps, recovering cubic boron nitride from the obtained sintered body by a chemical and/or physical manner.Type: GrantFiled: March 21, 1985Date of Patent: May 20, 1986Assignee: Toshiba Tungaloy Co., Ltd.Inventors: Shin-ichi Hirano, Shigeharu Naka
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Patent number: 4545968Abstract: There are disclosed methods for preparing cubic boron nitride sintered body. One method involves pyrolyzing borazine and/or a borazine derivative to obtain a boron nitride; mixing said boron nitride and a catalyst composed of a metal and/or metallic compound; and reacting the mixture at a pressure of 3 GPa or more and at a temperature of 700.degree. C. or more. Another method comprises the step of pyrolyzing borazine and/or a borazine derivative to obtain a boron nitride; mixing said boron nitride and a catalyst composed of a metal and/or metallic compound; reacting the mixture at a pressure of 3 GPa or more and at a temperature of 700.degree. C. or more; and removing the catalyst from a formed product. The conversion rate into cubic boron nitride achieved with these methods is as high as 100%, and the obtained cubic boron nitride is highly pure and fine.Type: GrantFiled: November 2, 1984Date of Patent: October 8, 1985Assignee: Toshiba Tungaloy Co., Ltd.Inventors: Shin-ichi Hirano, Shigeharu Naka