Abstract: Provided is a substance capable of effectively suppressing cancer metastasis or a pharmaceutical composition that effectively acts on an inflammatory disease. The pharmaceutical composition is a pharmaceutical composition containing, as an active ingredient, an antibody or an antibody fragment thereof having antigen-binding activity for an S100A8/A9 heterodimer, and blocks interaction between S100A8/A9 and a group of receptors therefor, to thereby strongly suppress cancer metastasis both in vitro and in vivo, or alleviate inflammation. That is, the anti-S100A8/A9 antibody or the antibody fragment thereof can strongly suppress cancer metastasis or alleviate inflammation, by virtue of its blocking action on the interaction between S100A8/A9 and the group of receptors therefor.

Abstract: A coil spring includes a wire rod and an elastic coat provided on the wire rod. The coil spring includes a coil section including a plurality of coil portions. The wire rod includes a round cross-sectional portion, a cross-section varying portion, and a rectangular cross-sectional portion along the longitudinal direction of the wire rod. The cross section of the rectangular cross-sectional portion is substantially square and has a first plane and a second plane. The first plane and the second plane oppose each other in the coil section. The elastic coat is provided on at least one of the first plane and the second plane. The elastic coat is continuous from the round cross-sectional portion to the cross-sectional variation portion and the rectangular cross-sectional portion.

Abstract: The present invention provides an electrolytic solution capable of providing an electrochemical device, such as a lithium ion secondary battery, or a module that has excellent high-temperature storage performance. The electrolytic solution contains: a homocyclic compound other than aromatic compounds; and a cyclic dicarbonyl compound. The homocyclic compound contains at least one group selected from the group consisting of a nitrile group and an isocyanate group.

Abstract: A vial supply system is provided with: a sampler configured to supply a vial to a predetermined supply destination by a transport arm; a management device communicatively connected to the sampler, the management device being configured to manage a supply operation of the vial by the sampler; and a display device provided so as to be able to communicate with the management device. When a teaching mode for performing teaching for setting a position of a transport arm at the time when a transport arm of the sampler transports the vial to and from the supply destination is started, the management device is configured to cause the display device to display an operation to be performed by a user in the teaching.

Abstract: An electrolyte solution for an alkali metal-sulfur-based secondary battery, an alkali metal-sulfur-based secondary battery, and a module containing the alkali metal-sulfur-based secondary battery. The electrolyte solution includes a positive electrode containing a carbon composite material that contains a carbon material and a sulfur-containing positive electrode active material. The carbon material has a pore volume ratio (micropores/mesopores) of 1.5 or higher. The electrolyte solution contains a fluorinated ether represented by the following formula (1): R11—(OR12)n11—O—R13. In the formula, R11 and R13 are the same as or different from each other, and are each an alkyl group optionally containing a fluorine atom, with at least one of R11 or R13 containing a fluorine atom; R12 is an alkylene group optionally containing a fluorine atom; and n11 is 0, 1, or 2.

Abstract: An electrochemical device which is an alkali metal battery or an alkaline earth metal battery, wherein only a positive electrode is an electrode having a perfluoropolyether group-containing compound in a surface thereof.

Abstract: A raindrop detection device 10 includes an LED 11, a photodiode 14, a microprocessor 20, and an LED flashing circuit 22. The LED 11 emits light in a specific direction. The photodiode 14 is disposed at a position opposite the LED 11 and receives light emitted from the LED 11. The microprocessor 20 detects raindrops that have passed between the LED 11 and the photodiode 14, according to the change in the amount of light received by the photodiode 14. The LED flashing circuit 22 controls the on and off switching of light emitted from the LED 11.

Abstract: A paper feeder includes a processor configured to, in a case of lowering a paper feed tray on which paper is placed in an accommodation section that accommodates paper and replenishing paper, the paper feed tray being controlled to be raised/lowered in a case of replenishing paper, control a lowering amount of the paper feed tray according to a number of sheets of paper to be replenished.

Abstract: An object is to provide a nonaqueous electrolyte and a nonaqueous-electrolyte secondary battery which have excellent discharge load characteristics and are excellent in high-temperature storability, cycle characteristics, high capacity, continuous-charge characteristics, storability, gas evolution inhibition during continuous charge, high-current-density charge/discharge characteristics, discharge load characteristics, etc. The object has been accomplished with a nonaqueous electrolyte which comprises: a monofluorophosphate and/or a difluorophosphate; and further a compound having a specific chemical structure or specific properties.

Abstract: An object is to provide a nonaqueous electrolyte and a nonaqueous-electrolyte secondary battery which have excellent discharge load characteristics and are excellent in high-temperature storability, cycle characteristics, high capacity, continuous-charge characteristics, storability, gas evolution inhibition during continuous charge, high-current-density charge/discharge characteristics, discharge load characteristics, etc. The object has been accomplished with a nonaqueous electrolyte which comprises: an acyclic carbonate having a halogen atom, a monofluorophosphate and/or a difluorophosphate; and further a compound having a specific chemical structure or specific properties.

Abstract: An object is to provide a nonaqueous electrolyte and a nonaqueous-electrolyte secondary battery which have excellent discharge load characteristics and are excellent in high-temperature storability, cycle characteristics, high capacity, continuous-charge characteristics, storability, gas evolution inhibition during continuous charge, high-current-density charge/discharge characteristics, discharge load characteristics, etc. The object has been accomplished with a nonaqueous electrolyte which comprises: a monofluorophosphate and/or a difluorophosphate; and further a compound having a specific chemical structure or specific properties.

Abstract: A method for producing a compound of formula (1) R11X11—SO3M11, which includes reacting a compound of formula (3) R31O—SO2—OR32 and a metal alkoxide, wherein R11, X11 and M11 are as defined herein.

Abstract: A non-aqueous liquid electrolyte secondary battery using negative-electrode active material having Si, Sn and/or Pb, with high charge-capacity, superior characteristics including discharge-capacity retention rate over long is provided. Its non-aqueous liquid electrolyte contains carbonate having unsaturated bond and/or halogen and compounds like LiPF6 and/or LiBF4 (first lithium salt) and lithium salt different from said first one, represented by formula below (second lithium salt). Lil(?mXan) (In the formula, l, m and n represent integers of 1 to 10, 1 to 100 and 1 to 200, respectively. ? represents boron, carbon, nitrogen, oxygen or phosphorus. Xa represents functional group having atom selected from 14th to 17th groups of periodic table at its binding-position to ?. Two or more of Xa may be connected to each other to form a ring structure. However, such a case where ? is boron and Xa is compound represented by (CiH2(i-2)O4)(CjH2(j-2)O4) is omitted (i and j represent integers of 2 or larger.

Abstract: An electrolyte solution for an electrochemical device, such as a lithium secondary battery, or module. The electrolyte solution contains: a solvent that contains a fluorinated acyclic carbonate having a fluorine content of 33 to 70 mass %; at least one organosilicon compound selected from a compound represented by the formula (1): (R11)n11—M11—O—SiR12R13R14 and a compound represented by the formula (2): R21R22R23—Si—F; a lithium salt (3) that contains an oxalato-complex as an anion; and a lithium salt (4) represented by the formula (4): LizM31FxOy, where R11, M11, R12, R13, R14, R21, R22, R23 and M31 are as defined herein.

Abstract: An electrochemical device which is an alkali metal battery or an alkaline earth metal battery, wherein only a positive electrode is an electrode having a perfluoropolyether group-containing compound in a surface thereof.

Abstract: A non-aqueous liquid electrolyte secondary battery using negative-electrode active material having Si, Sn and/or Pb, with high charge-capacity, superior characteristics including discharge-capacity retention rate over long is provided. Its non-aqueous liquid electrolyte contains carbonate having unsaturated bond and/or halogen and compounds like LiPF6 and/or LiBF4 (first lithium salt) and lithium salt different from said first one, represented by formula below (second lithium salt). Li1(?mXan) (In the formula, l, m and n represent integers of 1 to 10, 1 to 100 and 1 to 200, respectively. ? represents boron, carbon, nitrogen, oxygen or phosphorus. Xa represents functional group having atom selected from 14th to 17th groups of periodic table at its binding-position to ?. Two or more of Xa may be connected to each other to form a ring structure. However, such a case where a is boron and Xa is compound represented by (CiH2(i-2)O4)(CjH2(j-2)O4) is omitted (i and j represent integers of 2 or larger.).

Abstract: The present invention provides a novel electrolyte solution capable of providing electrochemical devices whose internal resistance is less likely to increase even after repeated charge and discharge and whose cycle capacity retention ratio is high. The electrolyte solution of the present invention contains a solvent, an electrolyte salt, and at least one selected from the group consisting of compounds represented by R11X11—SO3M11 and compounds represented by R21R22N—SO3M21 in an amount of 0.001 to 10 mass % relative to the solvent.

Abstract: The present invention relates to an electrode having a perfluoropolyether group-containing compound in a surface thereof.

Abstract: An electrolyte solution applicable to high-voltage electrochemical devices and capable of improving the cycle characteristics of electrochemical devices even at high voltage, and an electrochemical device. The electrolyte solution contains a fluorinated diether and a metal salt having a specific structure. The fluorinated diether is represented by CFR11R12—O—CH2CH2—O—R13, wherein R11 and R12 are each individually H, CH3, F, CH2F, CHF2, or CF3; and R13 is a C1 or C2 non-fluorinated alkyl group or a C1 or C2 fluorinated alkyl group.

Abstract: A paper feeder includes a processor configured to, in a case of lowering a paper feed tray on which paper is placed in an accommodation section that accommodates paper and replenishing paper, the paper feed tray being controlled to be raised/lowered in a case of replenishing paper, control a lowering amount of the paper feed tray according to a number of sheets of paper to be replenished.