Patents by Inventor Shin-ichi Yokota

Shin-ichi Yokota has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130323763
    Abstract: The present invention provides a useful examination method and diagnostic reagent, which are capable of diagnosing acute lung injury in clear distinction from chronic progressive interstitial pneumonia. Specifically, the present invention provides a method of determining whether or not a test subject is affected with acute lung injury, which comprises quantifying heat shock protein 47 in a biological sample derived from the test subject.
    Type: Application
    Filed: February 10, 2012
    Publication date: December 5, 2013
    Applicants: SAPPORO MEDICAL UNIVERSITY, NAGASAKI UNIVERSITY
    Inventors: Tomoyuki Kakugawa, Shin-ichi Yokota
  • Publication number: 20100022604
    Abstract: Disclosed is a novel therapeutic agent which is useful for the prevention or treatment of alopecia. Specifically disclosed is a prophylactic or therapeutic agent for alopecia, which comprises 1-[2-((2S)-2-{5-[(3,4-dimethoxyphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyrrolidin-1-yl)-1,1-difluoro-2-oxoethyl]-3,3,5,5-tetramethylcyclohexanol as an active ingredient.
    Type: Application
    Filed: December 20, 2007
    Publication date: January 28, 2010
    Applicant: TAISHO PHARMACEUTICAL CO., LTD.
    Inventors: Akiko Nakao, Natsuko Uematsu, Akiko Takahashi, Shin-ichi Yokota
  • Patent number: 6903116
    Abstract: A disease treatment is provided by controlling the expression of a protein induced by a heat shock factor. The novel compound benzo-1,3-dioxole provides an inhibitor of HSF activity or an inhibitor of inducing the production of a protein regulated by HSF, which inhibits the activity of a heat shock factor, a transcriptional regulatory factor, thereby in turn inhibiting transcription of a structural gene having a heat shock element sequenc in the gene region for transcriptional regulation into RNA, and thus inhibiting translation of the gene into a protein, and resulting in inhibition of inducing production of RNA or protein encoded by the gene. It also provides a drug for treating or preventing cancer through thermotherapy and a drug for treating or preventing stress diseases such as depression.
    Type: Grant
    Filed: January 9, 2003
    Date of Patent: June 7, 2005
    Assignee: Kaneka Corp.
    Inventors: Shin-ichi Yokota, Kozo Yamamoto, Souichi Morikawa, Yoshihide Fuse, Mikio Kitahara
  • Patent number: 6613780
    Abstract: A disease treatment is provided by controlling the expression of a protein induced by a heat shock factor. The novel compound benzo-1,3-dioxole provides an inhibitor of HSF activity or an inhibitor of inducing the production of a protein regulated by HSF, which inhibits the activity of a heat shock factor, a transcriptional regulatory factor, thereby in turn inhibiting transcription of a structural gene having a heat shock element sequence in the gene region for transcriptional regulation into RNA, and thus inhibiting translation of the gene into a protein, and resulting in inhibition of inducing production of RNA or protein encoded by the gene. It also provides a drug for treating or preventing cancer through thermotherapy and a drug for treating or preventing stress diseases such as depression.
    Type: Grant
    Filed: August 27, 2001
    Date of Patent: September 2, 2003
    Assignee: Kaneka Corporation
    Inventors: Shin-ichi Yokota, Kozo Yamamoto, Souichi Morikawa, Yoshihide Fuse, Mikio Kitahara
  • Publication number: 20030149077
    Abstract: A disease treatment is provided by controlling the expression of a protein induced by a heat shock factor.
    Type: Application
    Filed: January 9, 2003
    Publication date: August 7, 2003
    Inventors: Shin-Ichi Yokota, Kozo Yamamoto, Souichi Morikawa, Yoshihide Fuse, Mikio Kitahara
  • Publication number: 20020058679
    Abstract: A disease treatment is provided by controlling the expression of a protein induced by a heat shock factor.
    Type: Application
    Filed: August 27, 2001
    Publication date: May 16, 2002
    Inventors: Shin-Ichi Yokota, Kozo Yamamoto, Souichi Morikawa, Yoshihide Fuse, Mikio Kitahara
  • Patent number: 6281229
    Abstract: A disease treatment is provided by controlling the expression of a protein induced by a heat shock factor. The novel compound benzo-1,3-dioxole provides an inhibitor of HSF activity or an inhibitor of inducing the production of a protein regulated by HSF, which inhibits the activity of a heat shock factor, a transcriptional regulatory factor, thereby in turn inhibiting transcription of a structural gene having a heat shock element sequence in the gene region for transcriptional regulation into RNA, and thus inhibiting translation of the gene into a protein, and resulting in inhibition of inducing production of RNA or protein encoded by the gene. It also provides a drug for treating or preventing cancer through thermotherapy and a drug for treating or preventing stress diseases such as depression.
    Type: Grant
    Filed: March 27, 2000
    Date of Patent: August 28, 2001
    Assignee: Kaneka Corporation
    Inventors: Shin-ichi Yokota, Kozo Yamamoto, Souichi Morikawa, Yoshihide Fuse, Mikio Kitahara