Patents by Inventor Shin-ichiro Kawazu

Shin-ichiro Kawazu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8722909
    Abstract: The object is to develop an antiprotozoal remedy having a novel mechanism of action. Provided is a compound represented by a chemical formula (1), a prodrug or a pharmaceutically acceptable salt thereof, wherein within the formula (1), R1 represents R10— of formula (4) or R20— of formula (5); R2 represents CHO—, etc.; R3 represents a hydrogen atom, CH3—C(?O)—, etc.; R4 represents a hydrogen atom, CH3—C(?O)—, etc.; each of R11 and R12 independently represents a hydrogen atom, a methyl group, etc.; R13 represents —CH2—, —CH(—OH)— or —C(?O)—; each of R21 and R22 independently represents a hydrogen atom, a methyl group, etc.; R23 represents —CH2—, —CH(—OH)— or —C(?0)—; and R24 represents a hydrogen atom, a hydroxyl group, a methyl group, etc.
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: May 13, 2014
    Assignee: Waseda University
    Inventors: Yoichi Nakao, Shintaro Ishigami, Yasuyuki Goto, Shin-ichiro Kawazu, Noboru Inoue
  • Publication number: 20130296230
    Abstract: A method of the present invention for treating malaria includes the step of administering, to a human or an animal, a therapeutically effective amount of drug for suppressing calcium ion exit from an intracellular organelle of the malaria parasite to an outside of the intracellular organelle and/or calcium ion entry from an outside of a cell of the malaria parasite into the cell.
    Type: Application
    Filed: October 27, 2011
    Publication date: November 7, 2013
    Applicant: RIKEN
    Inventors: Katsuhiko Mikoshiba, Masahiro Enomoto, Shin-Ichiro Kawazu
  • Publication number: 20130005798
    Abstract: The object is to develop an antiprotozoal remedy having a novel mechanism of action. Provided is a compound represented by a chemical formula (1), a prodrug or a pharmaceutically acceptable salt thereof, wherein within the formula (1), R1 represents R10— of formula (4) or R20— of formula (5); R2 represents CHO—, etc.; R3 represents a hydrogen atom, CH3—C(?O)—, etc.; R4 represents a hydrogen atom, CH3—C(?O)—, etc.; each of R11 and R12 independently represents each a hydrogen atom, a methyl group, etc.; R13 represents —CH2—, —CH(—OH)— or —C(?O)—; each of R21 and R22 independently represents eaeh a hydrogen atom, a methyl group, etc.; R23 represents —CH2—, —CH(—OH)— or —C(?0)—; and R24 represents a hydrogen atom, a hydroxyl group, a methyl group, etc.
    Type: Application
    Filed: March 10, 2011
    Publication date: January 3, 2013
    Applicants: Obihiro University of Agriculture and Veterinary Medicine, Waseda University
    Inventors: Yoichi Nakao, Shintaro Ishigami, Yasuyuki Goto, Shin-ichiro Kawazu, Noboru Inoue
  • Patent number: 7713926
    Abstract: The peptide production method of the present invention produces a peptide (SEQ ID NO: 1) of a protein from Plasmodium falciparum, which is effective as a malaria vaccine. The method produces the peptide of SEQ ID NO: 1 by linking the fragments (i) through (v) shown below: (v) Asn-Asn-Asp-Xaa (SEQ ID NO: 2); (iv) Asp-Phe-Lys-Thr-Pro (SEQ ID NO: 3); (iii) Asn-Lys-Thr-Tyr-Asp-Leu (SEQ ID NO: 4); (ii) Phe-Tyr-Asn-Ser-Glu (SEQ ID NO: 5); and (i) Xaa-Ala-Ser-Glu (SEQ ID NO: 6), where ‘Xaa’ in (i) and (v) represents zero or any arbitrary number of amino acid residues.
    Type: Grant
    Filed: September 28, 2005
    Date of Patent: May 11, 2010
    Assignee: National University Corporation Gunma University
    Inventors: Hiroyuki Oku, Kazuto Omi, Keisuke Kuriyama, Jyunya Yamamoto, Keiichi Yamada, Ryoichi Katakai, Kumiko Sato, Mamoru Suzuki, Shin-ichiro Kawazu, Shigeyuki Kano
  • Publication number: 20070269377
    Abstract: F The peptide production method of the present invention produces a peptide (SEQ ID NO: 1) of a protein from Plasmodium falciparum, which is effective as a malaria vaccine. The method produces the peptide of SEQ ID NO: 1 by linking the fragments (i) through (v) shown below: (v) Asn-Asn-Asp-Xaa; (SEQ ID NO: 2) (iv) Asp-Phe-Lys-Thr-Pro; (SEQ ID NO: 3) (iii) Asn-Lys-Thr-Tyr-Asp-Leu; (SEQ ID NO: 4) (ii) Phe-Tyr-Asn-Ser-Glu; (SEQ ID NO: 5) and (i) Xaa-Ala-Ser-Glu, (SEQ ID NO: 6) where ‘Xaa’ in (i) and (v) represents zero or any arbitrary number of amino acid residues.
    Type: Application
    Filed: September 28, 2005
    Publication date: November 22, 2007
    Inventors: Hiroyuki Oku, Kazuto Omi, Kaisuke Kuriyama, Jyunya Yamamoto, Keiichi Yamada, Ryoichi Katakai, Kumiko Sato, Mamoru Suzuki, Shin-ichiro Kawazu, Shigeyuki Kano