Abstract: A catheter provided on the tip with a balloon of the type which can be inflated by being filled with a fluid, and particularly a catheter provided with a balloon around the inside circumference of which are formed multiple compartments. The direction of said catheter can be controlled at bifurcations in the blood vessel by supplying fluid through a fluid supply channel to at least one compartment so as to inflate the compartment corresponding to said channel.

Abstract: A laser beam guiding fiber comprising, in a tip portion of an optical fiber, an oscillating member which oscillates the tip of the optical fiber along a direction which intersects an axis of the optical fiber can irradiate a wide range with laser beam, since the tip of the optical fiber oscillates by means of the oscillating member along the direction which intersects the axis of the optical fiber and the irradiated position with the laser beam reciprocates periodically with the oscillation.

Abstract: A method of extracting a particular nucleic acid fragment containing a nucleic acid sequence of interest from a nucleic acid or nucleic acids mixture, comprising the steps of:(1) digesting the nucleic acid or nucleic acids mixture with restriction enzymes to obtain a mixture of nucleic acid fragments, said restriction enzymes consisting of (A) two different enzymes capable of producing the particular nucleic acid fragment bearing predetermined and distinct restriction ends on its 5' and 3' terminals and (B) one or more restriction enzymes different from (A), for which the particular nucleic acid fragment contains no relevant restriction sites;(2) preparing two distinct DNA linkers capable of binding to the respective restriction ends of the particular nucleic acid fragment;(3) allowing the linkers to react with the mixture of nucleic acid fragments;(4) subjecting the resulting reaction mixture to the first hybridization with an immobilized probe complementary to one of the linkers;(5) isolating the hybridized

Abstract: An optical fiber for laser beam guiding comprising a secondary non-linear optical element at one tip thereof can irradiate a lesion portion with a short wavelength beam useful for cure, since the non-linear optical element converts a long wavelength beam transmitted through the optical fiber to the short wavelength laser beam.

Abstract: A diagnostic and therapeutic catheter accommodating a plurality of optical fibers and tubes, including a small diameter portion formed at a distal end portion of the catheter, the small diameter portion having at least one duct, the optical fibers and the tubes confronting an inlet of the small diameter portion so as to be retractably inserted into the small diameter portion selectively.

Abstract: An intravascular laser operating device and method for examining and removing a diseased part in a blood vessel. The device includes a catheter having endoscopic fibers for performing an endoscopy and diagnostic of a diseased part in a blood vessel and laser light projecting fibers for projecting a laser light, a visible guide light, and an excited light to the diseased part. An laser device applies laser light to converting elements. A first wave length converting element converts part of the laser light into the visible guide light, and a second wave length converting element converts a part of the visible guide light into the excited light. The excited light is used for generating a fluorescent spectrum. An image is received representing the condition of the inside of the blood vessel based on image light received by the endoscopic fibers. A spectrum analyzing unit diagnoses the diseased part by obtaining the components of the fluorescent spectrum of the received image light.

Abstract: This invention relates to an intracavitary laser operating device using a laser.The device, has a catheter (2) accommodating laser light projecting fibers, a pulse laser oscillator device (1), an acoustic detector (4) detecting the acoustic wave generated from the diseased portion, an acoustic analyzer (5) analyzing the acoustic wave from the acoustic detector (4) and obtaining the amplitude change data and spectrum data of the acoustic wave, and a controller (7) for calculating the optimum condition of the projection of the laser light to be projected to the diseased part depending on the data from the acoustic analyzer (5) and controlling the pulse laser oscillator device (1) based on said optimum condition of the projection.

Abstract: An elastomeric optical waveguide comprising a core and a cladding surrounding the core in which at least the core comprises an elastomer to which elasticity is imparted by irradiation of a radioactive ray, which has low attenuation of light transmission.

Abstract: A cross-linked optical siloxane polymer having a group for modifying a refractive index of the polymer which is introduced in a side chain of the polymer by a hydrosilyl reaction of one of the following systems:(1) a compound (A) having a carbon-carbon unsaturated bond and a group for modifying a refractive index, and a siloxane polymer (B) having a silicon hydride group wherein the molar ratio of the silicon hydride group to the carbon-carbon unsaturated bond is more than 1, and(2) a compound (A') having a silicon hydride group and a group for modifying a refractive index, and a siloxane polymer (B') having a carbon-carbon unsaturated bond wherein the molar ratio of the carbon-carbon unsaturated bond to the silicon hydride group is more than 1,the polymer being cross-linked by a hydrosilyl reaction of the unreacted silicon hydride groups of the silixane polymer (B) with a compound (C) having at least two carbon-carbon unsaturated bonds when the system (1) is used, or by a hydrosilyl reaction of the unreacted

Abstract: An optical element integrated optical waveguide comprising (1) a polymeric supporting member a length of which lies in a light transmission direction and which has at least one bore along its entire length, (2) at least one optical waveguide part consisting of organic siloxane polymer filling at least one bore, and (3) at least one optical element embedded in the optical waveguide part is provided.

Abstract: An optical sensor which comprises an optical waveguide comprising a cladding and an optical waveguide member made of a transparent elastomer which is surrounded by the cladding and through which light is propagated, wherein an amount of light to be propagated through the waveguide member is changed according to a degree of elastic deformation of the waveguide member, which is not affected by electrical and/or magnetic fields.

Abstract: An elastomeric optical fiber comprising a core made of an elastomer with rubbery elasticity and a cladding surrounding the core and having low attenuation of light transmission is produced by a method comprising flowing down a liquid polymer for the core with cross-linking it, and simultaneously with or after the formation of the core, providing the cladding around the core.