Patents by Inventor Shin Iimura

Shin Iimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VLA-4 inhibitor compounds
    Patent number: 6756378
    Abstract: Compounds that selectively inhibit the binding of ligands to &agr;4&bgr;1 integrin (VLA-4) and methods for their preparation are disclosed. In one embodiment, compounds of the invention are represented by Formula I: As selective inhibitors of VLA-4 mediated cell adhesion, compounds of the present invention are useful in the treatment of conditions associated with such adhesion, including, but not limited to, such conditions as inflammatory and autoimmune responses, diabetes, asthma, psoriasis, inflammatory bowel disease, transplantation rejection, and tumor metastasis. Also disclosed are pharmaceutical compositions, methods of inhibiting VLA-4 mediated cell adhesion and methods of treating conditions associated with LA-4 mediated cell adhesion, which involve compounds of Formula I.
    Type: Grant
    Filed: December 28, 2001
    Date of Patent: June 29, 2004
    Assignees: Pharmacopeia Drug Discovery, Inc., Daiichi Pharmaceutical Co., Ltd.
    Inventors: John J. Baldwin, Edward McDonald, Kevin Joseph Moriarty, Christopher Ronald Sarko, Nobuo Machinaga, Atsushi Nakayama, Jun Chiba, Shin Iimura, Yoshiyuki Yoneda
  • Vla-4 inhibitors
    Publication number: 20040110945
    Abstract: The present invention relates to a compound represented by the following formula (I): 1
    Type: Application
    Filed: June 30, 2003
    Publication date: June 10, 2004
    Inventors: Atsushi Nakayama, Nobuo Machinaga, Yoshiyuki Yoneda, Yuichi Sugimoto, Jun Chiba, Toshiyuki Watanabe, Shin Iimura
  • VLA-4 inhibitor compounds
    Publication number: 20030078249
    Abstract: Compounds that selectively inhibit the binding of ligands to &agr;4&bgr;1 integrin (VLA-4) and methods for their preparation are disclosed.
    Type: Application
    Filed: December 28, 2001
    Publication date: April 24, 2003
    Applicant: Daiichi Pharmaceutical Co., LTD.
    Inventors: John J. Baldwin, Edward McDonald, Kevin Joseph Moriarty, Christopher Ronald Sarko, Nobuo Machinaga, Atsushi Nakayama, Jun Chiba, Shin Iimura, Yoshiyuki Yoneda