Abstract: The present disclosure provides compounds and processes for the preparation of hypomethylating agents, including guadecitabine and salts thereof. The present disclosure also provides solid forms of guadecitabine sodium, including polymorphs that can exhibit decreased hygroscopicity and increased stability relative to other solid forms.

Abstract: A painting device is provided with: a bell-shaped cup for discharging paint; a housing for holding the cup so as to be freely rotatable; and first tip openings disposed on the outside in the radial direction on the base end side of the tip side outer peripheral edge of the cup and throwing paint onto a workpiece by spraying shaping air in the direction of the tip. When a tangent line that is tangent to the tip side outer peripheral edge of the cup from a first tip opening is drawn in a front view of the painting device, the first tip opening sprays shaping air at an inclination more to the inside in the radial direction of the cup than the tangent line.

Abstract: A painting device is provided with: a bell-shaped cup for discharging paint; a housing for holding the cup so as to be freely rotatable; and first tip openings disposed on the outside in the radial direction on the base end side of the tip side outer peripheral edge of the cup and throwing paint onto a workpiece by spraying shaping air in the direction of the tip. When a tangent line that is tangent to the tip side outer peripheral edge of the cup from a first tip opening is drawn in a front view of the painting device, the first tip opening sprays shaping air at an inclination more to the inside in the radial direction of the cup than the tangent line.

Abstract: The present invention provides a method for producing a compound of Formula (4): wherein R1 is a hydrogen atom etc. by reacting a compound of Formula (2): wherein X1 is a leaving group, with a compound of Formula (3): wherein R1 is as defined above, in the presence of (a) a palladium compound and a tertiary phosphine or (b) a palladium carbene complex, in an inert solvent or without a solvent. The present invention can produce the compound of Formula (4), with high purity and high yield, and by a simple operation.

Abstract: The present invention provides a method for producing a compound of Formula (4): wherein R1 is a hydrogen atom etc. by reacting a compound of Formula (2): wherein X1 is a leaving group, with a compound of Formula (3): wherein R1 is as defined above, in the presence of (a) a palladium compound and a tertiary phosphine or (b) a palladium carbene complex, in an inert solvent or without a solvent. The present invention can produce the compound of Formula (4), with high purity and high yield, and by a simple operation.

Abstract: An object of the present invention is to provide a method for producing an oxazole compound in a high yield.

Abstract: An object of the present invention is to provide a method for producing an oxazole compound in a high yield.

Abstract: The present invention relates to organic polymer porous materials, and in particular, to an organic polymer porous material that functions as a reusable insoluble solid catalyst and a method for producing the same. The organic polymer porous material of the present invention is characteristic in that the amount of immobilized bases is high and the specific surface area is large. The object has been achieved by an organic polymer porous material including a polymer (PA) obtained by polymerizing a polymerizable composition (A) containing a compound (a) obtained by reacting a dendrimer (a1) having at least an amino group as a reactive functional group or a polyethyleneimine (a2) having at least an amino group as a reactive functional group with a compound (a3) having a vinyl group and a group that can react with the reactive functional group.

Abstract: The present invention relates to organic polymer porous materials, and in particular, to an organic polymer porous material that functions as a reusable insoluble solid catalyst and a method for producing the same. The organic polymer porous material of the present invention is characteristic in that the amount of immobilized bases is high and the specific surface area is large. The object has been achieved by an organic polymer porous material including a polymer (PA) obtained by polymerizing a polymerizable composition (A) containing a compound (a) obtained by reacting a dendrimer (a1) having at least an amino group as a reactive functional group or a polyethyleneimine (a2) having at least an amino group as a reactive functional group with a compound (a3) having a vinyl group and a group that can react with the reactive functional group.