Patents by Inventor Shin Sugimoto
Shin Sugimoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11759456Abstract: Provided is a pharmaceutical composition containing pemafibrate, a salt thereof or a solvate thereof and having excellent homogeneity. The pharmaceutical composition contains pemafibrate, a salt thereof or a solvate thereof in an amount of 0.017 to 4.2 mass % in terms of a free form of pemafibrate with respect to the total mass of the pharmaceutical composition.Type: GrantFiled: June 29, 2018Date of Patent: September 19, 2023Assignee: KOWA COMPANY, LTD.Inventors: Shin Sugimoto, Akito Minamizono
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Patent number: 11730719Abstract: Provided is a pharmaceutical composition which contains pemafibrate, a salt thereof or a solvate thereof and has excellent stability. A pharmaceutical composition is provided containing pemafibrate, a salt thereof or a solvate thereof and having a moisture content of 2.4 mass % or less.Type: GrantFiled: February 2, 2022Date of Patent: August 22, 2023Assignee: KOWA COMPANY, LTD.Inventors: Shin Sugimoto, Akito Minamizono
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Publication number: 20230190712Abstract: Provided is a pharmaceutical composition containing pemafibrate, a salt thereof or a solvate thereof and having excellent homogeneity. The pharmaceutical composition is provided to contain the following components (A) and (B): (A) pemafibrate, a salt thereof or a solvate thereof; and (B) one or more selected from the group consisting of the following components (B-1) to (B-6): (B-1) a cellulose ether species; (B-2) a starch species; (B-3) a povidone species; (B-4) a silicic acid compound; (B-5) a polyhydric alcohol; and (B-6) an alkyl sulfate ester.Type: ApplicationFiled: February 22, 2023Publication date: June 22, 2023Applicant: KOWA COMPANY, LTD.Inventors: Shin SUGIMOTO, Akito MINAMIZONO
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Patent number: 11419855Abstract: Provided is a novel technique for improving storage stability of a pharmaceutical composition containing pemafibrate, a salt thereof or a solvate thereof and a cellulose species. A pharmaceutical preparation obtained by storing a pharmaceutical composition containing the following components (A) and (B) in a tight package: (A) pemafibrate, a salt thereof or a solvate thereof; and (B) a cellulose species.Type: GrantFiled: June 29, 2018Date of Patent: August 23, 2022Assignee: KOWA COMPANY, LTD.Inventors: Shin Sugimoto, Akito Minamizono
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Patent number: 11406621Abstract: Provided is a pharmaceutical composition containing pemafibrate, a salt thereof or a solvate thereof and having excellent homogeneity. The pharmaceutical composition is provided containing the following components (A) and (B): (A) pemafibrate, a salt thereof or a solvate thereof; and (B) a disaccharide species.Type: GrantFiled: June 29, 2018Date of Patent: August 9, 2022Assignee: KOWA COMPANY, LTD.Inventors: Shin Sugimoto, Akito Minamizono
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Publication number: 20220151996Abstract: Provided is a pharmaceutical composition which contains pemafibrate, a salt thereof or a solvate thereof and has excellent stability. A pharmaceutical composition is provided containing pemafibrate, a salt thereof or a solvate thereof and having a moisture content of 2.4 mass % or less.Type: ApplicationFiled: February 2, 2022Publication date: May 19, 2022Applicant: KOWA COMPANY, LTD.Inventors: Shin SUGIMOTO, Akito MINAMIZONO
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Patent number: 11298340Abstract: Provided is a pharmaceutical composition which contains pemafibrate, a salt thereof or a solvate thereof and has excellent stability. A pharmaceutical composition is provided containing pemafibrate, a salt thereof or a solvate thereof and having a moisture content of 2.4 mass % or less.Type: GrantFiled: June 29, 2018Date of Patent: April 12, 2022Assignee: KOWA COMPANY, LTD.Inventors: Shin Sugimoto, Akito Minamizono
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Publication number: 20220096443Abstract: Provided is a pharmaceutical composition containing pemafibrate, a salt thereof or a solvate thereof and having excellent homogeneity. The pharmaceutical composition is provided to contain the following components (A) and (B): (A) pemafibrate, a salt thereof or a solvate thereof; and (B) one or more selected from the group consisting of the following components (B-1) and (B-7): (B-1) an alkylcellulose and a salt thereof; and a (meth)acrylic acid-based polymer.Type: ApplicationFiled: December 27, 2019Publication date: March 31, 2022Applicant: KOWA COMPANY, LTD.Inventors: Shin SUGIMOTO, Akito MINAMIZONO, Chisa NISHIDA
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Publication number: 20220047585Abstract: A preventing or treating agent for glaucoma is provided. This drug has a strong action of reducing intraocular pressure such that the intraocular pressure can be reduced even from the normal intraocular pressure. More specifically, a prophylactic or therapeutic agent for glaucoma, a preventing or treating agent for ocular hypertension, and eye drops containing (S)-(?)-1-(4-fluoro-5-isoquinolinesulfonyl)-2-methyl homopiperazine or its salt and phosphoric acid or its salt are provided.Type: ApplicationFiled: November 1, 2021Publication date: February 17, 2022Applicant: KOWA CO., LTD.Inventors: Shin SUGIMOTO, Ken MIZUNO, Masatoshi TAKAHASHI, Makoto KANEBAKO
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Publication number: 20200179346Abstract: Provided is a pharmaceutical composition containing pemafibrate, a salt thereof or a solvate thereof and having excellent homogeneity. The pharmaceutical composition contains pemafibrate, a salt thereof or a solvate thereof in an amount of 0.017 to 4.2 mass % in terms of a free form of pemafibrate with respect to the total mass of the pharmaceutical composition.Type: ApplicationFiled: June 29, 2018Publication date: June 11, 2020Applicant: KOWA COMPANY, LTD.Inventors: Shin SUGIMOTO, Akito MINAMIZONO
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Publication number: 20200155514Abstract: Provided is a pharmaceutical composition containing pemafibrate, a salt thereof or a solvate thereof and having excellent homogeneity. The pharmaceutical composition is provided containing the following components (A) and (B): (A) pemafibrate, a salt thereof or a solvate thereof; and (B) a disaccharide species.Type: ApplicationFiled: June 29, 2018Publication date: May 21, 2020Applicant: KOWA COMPANY, LTD.Inventors: Shin SUGIMOTO, Akito MINAMIZONO
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Publication number: 20200129483Abstract: Provided is a pharmaceutical composition containing pemafibrate, a salt thereof or a solvate thereof and having excellent homogeneity. The pharmaceutical composition is provided to contain the following components (A) and (B): (A) pemafibrate, a salt thereof or a solvate thereof; and (B) one or more selected from the group consisting of the following components (B-1) to (B-6): (B-1) a cellulose ether species; (B-2) a starch species; (B-3) a povidone species; (B-4) a silicic acid compound; (B-5) a polyhydric alcohol; and (B-6) an alkyl sulfate ester.Type: ApplicationFiled: June 29, 2018Publication date: April 30, 2020Applicant: KOWA COMPANY, LTD.Inventors: Shin SUGIMOTO, Akito MINAMIZONO
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Publication number: 20200121649Abstract: Provided is a novel technique for improving storage stability of a pharmaceutical composition containing pemafibrate, a salt thereof or a solvate thereof and a cellulose species. A pharmaceutical preparation obtained by storing a pharmaceutical composition containing the following components (A) and (B) in a tight package: (A) pemafibrate, a salt thereof or a solvate thereof; and (B) a cellulose species.Type: ApplicationFiled: June 29, 2018Publication date: April 23, 2020Applicant: KOWA COMPANY, LTD.Inventors: Shin SUGIMOTO, Akito MINAMIZONO
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Publication number: 20200121650Abstract: Provided is a pharmaceutical composition which contains pemafibrate, a salt thereof or a solvate thereof and has excellent stability. Apharmaceutical composition is provided containing pemafibrate, a salt thereof or a solvate thereof and having a moisture content of 2.4 mass % or less.Type: ApplicationFiled: June 29, 2018Publication date: April 23, 2020Applicant: KOWA COMPANY, LTD.Inventors: Shin SUGIMOTO, Akito MINAMIZONO
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Publication number: 20190328730Abstract: A preventing or treating agent for glaucoma is provided. This drug has a strong action of reducing intraocular pressure such that the intraocular pressure can be reduced even from the normal intraocular pressure. More specifically, a prophylactic or therapeutic agent for glaucoma, a preventing or treating agent for ocular hypertension, and eye drops containing (S)-(?)-1-(4-fluoro-5-isoquinolinesulfonyl)-2-methyl homopiperazine or its salt and phosphoric acid or its salt are provided.Type: ApplicationFiled: July 8, 2019Publication date: October 31, 2019Applicant: KOWA CO., LTD.Inventors: Shin SUGIMOTO, Ken MIZUNO, Masatoshi TAKAHASHI, Makoto KANEBAKO
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Patent number: 10376523Abstract: An aqueous composition having an excellent antiseptic effect is provided. An aqueous composition containing: a compound represented by Formula (1), a salt thereof, or a solvate of the compound or the salt thereof, where X represents a halogen atom, and a quaternary ammonium surfactant. A method for producing an aqueous composition with an antiseptic effect, by incorporating a compound represented by Formula (1), a salt thereof, or a solvate of the compound or the salt thereof and a quaternary ammonium surfactant into the aqueous composition.Type: GrantFiled: September 25, 2015Date of Patent: August 13, 2019Assignee: KOWA COMPANY, LTD.Inventor: Shin Sugimoto
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Publication number: 20170290841Abstract: An aqueous composition having an excellent antiseptic effect is provided. An aqueous composition comprising a compound represented by Formula (1), wherein X represents a halogen atom, or a salt thereof, or a solvate of the compound or the salt thereof, and a quaternary ammonium surfactant.Type: ApplicationFiled: September 25, 2015Publication date: October 12, 2017Applicant: KOWA COMPANY, LTD.Inventor: Shin SUGIMOTO
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Publication number: 20170266080Abstract: A technique is provided for suppressing discoloration of an aqueous composition containing a halogenated isoquinoline derivative during preservation at high temperature. A pharmaceutical preparation obtained by storing an aqueous composition comprising a compound represented by Formula (1), wherein X represents a halogen atom, or a salt thereof, or a solvate of the compound or the salt thereof, in a container made of polyolefin-based resin.Type: ApplicationFiled: September 25, 2015Publication date: September 21, 2017Applicant: KOWA COMPANY, LTD.Inventor: Shin SUGIMOTO
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Publication number: 20100233287Abstract: A preventing or treating agent for glaucoma is provided. This drug has a strong action of reducing intraocular pressure such that the intraocular pressure can be reduced even from the normal intraocular pressure. More specifically, a prophylactic or therapeutic agent for glaucoma, a preventing or treating agent for ocular hypertension, and eye drops containing (S)-(?)-1-(4-fluoro-5-isoquinolinesulfonyl)-2-methyl homopiperazine or its salt and phosphoric acid or its salt are provided.Type: ApplicationFiled: May 24, 2010Publication date: September 16, 2010Applicant: Kowa Co., Ltd.Inventors: Shin Sugimoto, Ken Mizuno, Masatoshi Takahashi, Makoto Kanebako
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Publication number: 20060142270Abstract: A preventing or treating agent for glaucoma is provided. This drug has a strong action of reducing intraocular pressure such that the intraocular pressure can be reduced even from the normal intraocular pressure. More specifically, a prophylactic or therapeutic agent for glaucoma, a preventing or treating agent for ocular hypertension, and eye drops containing (S)-(-)-1-(4-fluoro-5-isoquinolinesulfonyl)-2-methyl homopiperazine or its salt and phosphoric acid or its salt are provided.Type: ApplicationFiled: December 14, 2005Publication date: June 29, 2006Applicant: Kowa Co., Ltd.Inventors: Shin Sugimoto, Ken Mizuno, Masatoshi Takahashi, Makoto Kanebako