Abstract: The present invention implements an ion detector with which it is possible to avoid direct collisions of negative ions with a scintillator, prevent degradation of the scintillator, prolong life of the scintillator, reduce the need for maintenance, and perform highly sensitive detection of both positive and negative ions. With respect to a reference line 65 connecting a central point 63 of a positive ion CD 52 and a central point 64 of a counter electrode 54, a central point 66 of a negative ion CD 53 is provided in a region of a side opposite to a region of a side of a central point 67 of a scintillator 56. Positive ions entering from an ion entrance 62 receive a deflection force and collide with the positive ion CD 52 to generate secondary electrons. The generated secondary electrons collide with the scintillator 56 to generate light. The generated light passes through a light guide 59 and is detected by a photomultiplier tube 58. A negative potential barrier is generated along the reference line 65.

Abstract: An inductor component and a method for manufacturing an inductor component that enables miniaturization of the inductor component. An inductor component includes an annular core; and a coil including a plurality of pin members and wound on the core with neighboring pin members connected to each other. A first pin member and a second pin member both adjacent to each other have a welded part in which an end face of an end part of the first pin member and a peripheral surface of an end part of the second pin member are welded to each other. The welded part is not provided on an outer side edge of the second pin member as viewed from a direction orthogonal to a first plane containing a center line of the end part of the first pin member and a center line of the end part of the second pin member.

Abstract: The management device of an autonomous driving vehicle includes a congestion rate calculation unit and a waiting place setting unit. The congestion rate calculation unit is able to calculate the congestion rate of a parking lot adjoining each of a plurality of commercial facilities. In a case where the congestion rate of a neighbor parking lot, or a parking lot in the neighborhood of a boarding place contained in reservation information for an autonomous driving vehicle reserved for dispatch, during a waiting time period before the scheduled boarding time, is less than a congestion threshold, the waiting place setting unit sets the neighbor parking lot as a waiting place for the autonomous driving vehicle to wait during the waiting time period.

Abstract: An autonomous vehicle allows passengers to transfer from a passenger vehicle, which is a relatively large vehicle, to the autonomous vehicle. The autonomous vehicle is provided with an autonomous travel control unit (steering control unit) configured to, when the passenger vehicle is stopped, cause the autonomous vehicle to pull up alongside the passenger vehicle such that an entrance (second entrance) of the autonomous vehicle is placed next to an entrance (first entrance) of the passenger vehicle.

Abstract: Image display device and method have a display arranged at a user's preferred position and displaying images with comfortable image quality and arrangement that match a user's viewing position and preference. The image display device includes an external input interface, a memory for storing image data, an arithmetic processing unit, a graphics processing unit, a display, and a setting mode suitable for the user.

Abstract: The wearable measurement device includes a mounting part for mounting the device to a human body, a variation detection part detecting a variation in distance from a predetermined portion of the human body, a posture detection part detecting a posture of the variation detection part in the case where the device is mounted to the human body through the mounting part, and a measurement part measuring the number of predetermined motions based on the variation detected by the variation detection part and the posture detected by the posture detection part. The variation detection part includes a light emitting unit and a light receiving unit, makes the light emitting unit emit light and the light receiving unit detect reflection light reflected at a predetermined portion, detects a distance from the predetermined portion and outputs an electric signal (voltage or current) in accordance with the detected distance at a predetermined sampling cycle.

Abstract: An elongated member such as a bar includes spaced-apart infrared light illumination ports at opposite ends thereof. Exemplary spacing between the two spaced-apart light ports may be 20 centimeters or more. Each light port comprises an array of plural light sources. The plural light sources in each array may be directionally aimed to as to provide different illumination directions. The plural light sources in each array may emit different colors or frequencies of light. Example applications include targeting or marking capabilities for a video game or other system handheld pointing device.

Abstract: An elongated member such as a bar includes spaced-apart infrared light illumination ports at opposite ends thereof. Exemplary spacing between the two spaced-apart light ports may be 20 centimeters or more. Each light port comprises an array of plural light sources. The plural light sources in each array may be directionally aimed to as to provide different illumination directions. The plural light sources in each array may emit different colors or frequencies of light. Example applications include targeting or marking capabilities for a video game or other system handheld pointing device.

Abstract: Analogs of cyclosporin-A are disclosed comprising modifications of the substituents as the positions of amino acids 1 and 3, according to the following Formula. The disclosed compounds include compounds having affinity for cyclophilin, including cyclophilin-A, and reduced immunosuppressivity in comparison with cyclosporin-A and analogs thereof modified solely at position 1.

Abstract: An elongated member such as a bar includes spaced-apart infrared light illumination ports at opposite ends thereof. Exemplary spacing between the two spaced-apart light ports may be 20 centimeters or more. Each light port comprises an array of plural light sources. The plural light sources in each array may be directionally aimed to as to provide different illumination directions. The plural light sources in each array may emit different colors or frequencies of light. Example applications include targeting or marking capabilities for a video game or other system handheld pointing device.

Abstract: The wearable measurement device includes a mounting part for mounting the device to a human body, a variation detection part detecting a variation in distance from a predetermined portion of the human body, a posture detection part detecting a posture of the variation detection part in the case where the device is mounted to the human body through the mounting part, and a measurement part measuring the number of predetermined motions based on the variation detected by the variation detection part and the posture detected by the posture detection part. The variation detection part includes a light emitting unit and a light receiving unit, makes the light emitting unit emit light and the light receiving unit detect reflection light reflected at a predetermined portion, detects a distance from the predetermined portion and outputs an electric signal (voltage or current) in accordance with the detected distance at a predetermined sampling cycle.

Abstract: The wearable measurement device includes a mounting part for mounting the device to a human body, a variation detection part detecting the movement of a predetermined portion of the human body while not being in contact with the predetermined portion, and a measurement part measuring the number of predetermined motions or time of motion based on the movement detected by the variation detection part. The variation detection part includes a light emitting unit and a light receiving unit, makes the light emitting unit emit light and the light receiving unit detect reflection light reflected at a predetermined portion, detects a distance from the predetermined portion and outputs an electric signal (voltage or current) in accordance with the detected distance at a predetermined sampling cycle.

Abstract: An elongated member such as a bar includes spaced-apart infrared light illumination ports at opposite ends thereof. Exemplary spacing between the two spaced-apart light ports may be 20 centimeters or more. Each light port comprises an array of plural light sources. The plural light sources in each array may be directionally aimed to as to provide different illumination directions. The plural light sources in each array may emit different colors or frequencies of light. Example applications include targeting or marking capabilities for a video game or other system handheld pointing device.

Abstract: Analogues of cyclosporin-A are disclosed comprising modifications of the substituents as the positions of amino acids 1 and 3, according to the following Formula. The disclosed compounds include compounds having affinity for cyclophilin, including cyclophilin-A, and reduced immunosuppressivity in comparison with cyclosporin-A and analogs thereof modified solely at position 1.

Abstract: An elongated member such as a bar includes spaced-apart infrared light illumination ports at opposite ends thereof. Exemplary spacing between the two spaced-apart light ports may be 20 centimeters or more. Each light port comprises an array of plural light sources. The plural light sources in each array may be directionally aimed to as to provide different illumination directions. The plural light sources in each array may emit different colors or frequencies of light. Example applications include targeting or marking capabilities for a video game or other system handheld pointing device.

Abstract: Analogs of cyclosporin-A are disclosed comprising modifications of the substituents as the positions of amino acids 1 and 3, according to the following Formula. The disclosed compounds include compounds having affinity for cyclophilin, including cyclophilin-A, and reduced immunosuppressivity in comparison with cyclosporin-A and analogs thereof modified solely at position 1.

Abstract: Analogues of cyclosporin-A are disclosed comprising modifications of the substituents as the positions of amino acids 1 and 3, according to the following Formula. The disclosed compounds include compounds having affinity for cyclophilin, including cyclophilin-A, and reduced immunosuppressivity in comparison with cyclosporin-A and analogs thereof modified solely at position 1.

Abstract: The compounds of the present invention are non-immunosupressive cyclosporine analogue molecules that are able to bind cyclophilin. Said compounds include a modified side chain of amino acid I of cyclosporin A, consisting of an oxyalkyl having substituents R?, R1 and R2, where R? is H or Acetyl; R1 is a saturated or unsaturated straight chain or branched aliphatic carbon chain; and R2 may be a hydrogen; a unsubstituted, N substituted or NN disubstituted amide; a N substituted or unsubstituted acyl protected amine; a carboxylic acid; a N substituted or unsubstituted amine; a nitrile; a ester; a ketone; a hydroxy, dihydroxy, trihydroxy or polyhydroxy alkyl; or a substituted or unsubstituted aryl.

Abstract: Isolated metabolites of the cyclosporine analog ISA247 are disclosed, including in vitro methods for their preparation. The metabolites comprise a chemical modification of ISA247, wherein the modification is at least one reaction selected from the group consisting of hydroxylation, N-demethylation, diol formation, epoxide formation, and intramolecular cyclization phosphorylation, sulfation, glucuronide formation and glycosylation. Methods of preparation include semi-synthetic methods, wherein metabolites of ISA247 are produced from the microsomal extracts of animal liver cells, or from cultures using microorganisms, and completely synthetic methods, such as chemically modifying the parent compound or isolated metabolites using organic synthetic methods.

Abstract: The present multiple-stage optical isolator has low polarization-dependency and low polarization-mode dispersion but does not require a long time for the assembly. It is constructed of a first unit having a first Faraday rotator placed within a magnetic field and at least one birefringent crystal sandwiching the Faraday rotator, these components being arranged in order from the light incident side; and a second unit having a second Faraday rotator placed within a magnetic field and at least one birefringent crystal sandwiching the Faraday rotator, these components being arranged in order from the light incident side, wherein the first and second units are arranged in order along the direction of the light transmission.