Patents by Inventor Shingai Majuru

Shingai Majuru has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline polymorphic forms of monosodium n-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 11395809
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino] caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-V). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: July 30, 2020
    Date of Patent: July 26, 2022
    Assignee: NOVO NORDISK NORTH AMERICA OPERATIONS A/S
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • CRYSTALLINE POLYMORPHIC FORMS OF MONOSODIUM N-[-8-(2-HYDROXYBENZOYL)AMINO]CAPRYLATE
    Publication number: 20210177792
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino] caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-V). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: July 30, 2020
    Publication date: June 17, 2021
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • Crystalline polymorphic forms of monosodium N-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 10744105
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: August 18, 2020
    Assignee: Emisphere Technologies, Inc.
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • CRYSTALLINE POLYMORPHIC FORMS OF MONOSODIUM N-[-8-(2-HYDROXYBENZOYL)AMINO]CAPRYLATE
    Publication number: 20190343786
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: December 6, 2018
    Publication date: November 14, 2019
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • Gastric Retention and Controlled Release Delivery System
    Publication number: 20190216729
    Abstract: The present invention relates to gastric retention delivery systems and controlled release compositions containing a pharmaceutically acceptable active agent and a delivery agent.
    Type: Application
    Filed: December 18, 2017
    Publication date: July 18, 2019
    Inventors: Jun Liao, Puchun Liu, Steven Dinh, Brahma Singh, Shingai Majuru, Prateek N. Bhargava
  • POWDER ORAL SUSPENSION FORMULATIONS OF ANTIBACTERIAL AGENTS
    Publication number: 20190209530
    Abstract: Powder oral suspension formulations of antibacterial compounds are described herein. In addition, reconstitutable powders of antibacterial compounds and oral suspension formulations thereof are described herein.
    Type: Application
    Filed: September 13, 2018
    Publication date: July 11, 2019
    Inventors: David Eugene PEREIRA, Shingai MAJURU, Prabhavathi FERNANDES
  • Crystalline polymorphic forms of monosodium N-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 10188621
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: August 3, 2017
    Date of Patent: January 29, 2019
    Assignee: EMISPHERE TECHNOLOGIES, INC.
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • PHARMACEUTICAL FORMULATIONS CONTAINING MICROPARTICLES OR NANOPARTICLES OF A DELIVERY AGENT
    Publication number: 20190022228
    Abstract: This invention relates to microparticles and/or nanoparticles containing a delivery agent and/or an active agent. This invention also relates to pharmaceutical formulations and solid dosage forms, including controlled release solid dosage forms of active agent and a delivery agent.
    Type: Application
    Filed: February 12, 2018
    Publication date: January 24, 2019
    Inventors: George Klein, Shingai Majuru, Puchun Liu, Steven Dinh, Jun Liao, Jongbin Lee, Halina Levchik, Ehud Arbit, Nikhil Dhoot, Jamila Harris, Nai Fang Wang
  • Silk-based capsules
    Patent number: 10182991
    Abstract: A hard or soft capsule is disclosed comprising a shell and a fill material, wherein the shell comprises an interpenetrating network comprising a silk polymer and a film-forming natural polymer. A method of making a hard or soft capsule is also disclosed, comprising dissolving a silk protein in a solvent system to form a solubilized silk protein solution; mixing the solubilized silk protein solution with a film-forming natural polymer to form a homogenous shell material; and encapsulating a fill material with the homogenous shell material.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: January 22, 2019
    Assignee: Patheon Softgels Inc.
    Inventors: Tatyana Dyakonov, Derek Bush, Saujanya L. Gosangari, Chue Hue Yang, Shingai Majuru, Aqeel Fatmi
  • FORMULATIONS FOR DELIVERING INSULIN
    Publication number: 20180338923
    Abstract: Oral insulin formulations and processes for preparing oral insulin formulations are provided.
    Type: Application
    Filed: January 19, 2018
    Publication date: November 29, 2018
    Inventors: Halina LEVCHIK, Moses OYEWUMI, Shingai MAJURU, William E. BAY, Jun LIAO, Puchun LIU, Steven DINH, Nikhil DHOOT
  • SILK-BASED CAPSULES
    Publication number: 20180235892
    Abstract: A hard or soft capsule is disclosed comprising a shell and a fill material, wherein the shell comprises an interpenetrating network comprising a silk polymer and a film-forming natural polymer. A method of making a hard or soft capsule is also disclosed, comprising dissolving a silk protein in a solvent system to form a solubilized silk protein solution; mixing the solubilized silk protein solution with a film-forming natural polymer to form a homogenous shell material; and encapsulating a fill material with the homogenous shell material.
    Type: Application
    Filed: April 23, 2018
    Publication date: August 23, 2018
    Inventors: Tatyana DYAKONOV, Derek BUSH, Saujanya L. GOSANGARI, Chue Hue YANG, Shingai MAJURU, Aqeel FATMI
  • Silk-based capsules
    Patent number: 9968561
    Abstract: A hard or soft capsule is disclosed comprising a shell and a fill material, wherein the shell comprises an interpenetrating network comprising a silk polymer and a film-forming natural polymer. A method of making a hard or soft capsule is also disclosed, comprising dissolving a silk protein in a solvent system to form a solubilized silk protein solution; mixing the solubilized silk protein solution with a film-forming natural polymer to form a homogenous shell material; and encapsulating a fill material with the homogenous shell material.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: May 15, 2018
    Assignee: Patheon Softgels Inc.
    Inventors: Tatyana Dyakonov, Derek Bush, Saujanya L. Gosangari, Yang Hue Chue, Shingai Majuru, Aqeel Fatmi
  • CRYSTALLINE POLYMORPHIC FORMS OF MONOSODIUM N-[-8-(2-HYDROXYBENZOYL)AMINO]CAPRYLATE
    Publication number: 20170326087
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino] caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: August 3, 2017
    Publication date: November 16, 2017
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • Crystalline polymorphic forms of monosodium N-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 9750710
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: September 5, 2017
    Assignee: Emisphere Technologies, Inc.
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • POWDER ORAL SUSPENSION FORMULATIONS OF ANTIBACTERIAL AGENTS
    Publication number: 20170224664
    Abstract: Powder oral suspension formulations of antibacterial compounds are described herein. In addition, reconstitutable powders of antibacterial compounds and oral suspension formulations thereof are described herein.
    Type: Application
    Filed: August 5, 2015
    Publication date: August 10, 2017
    Inventors: David Eugene PEREIRA, Shingai MAJURU, Prabhavathi FERNANDES
  • CRYSTALLINE POLYMORPHIC FORMS OF MONOSODIUM N-[-8-(2-HYDROXYBENZOYL)AMINO]CAPRYLATE
    Publication number: 20160184251
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Application
    Filed: February 22, 2016
    Publication date: June 30, 2016
    Inventors: Halina LEVCHIK, Shingai MAJURU, Brahma SINGH, Jamila HARRIS
  • Solid pharmaceutical dosage forms comprising bisphosphonates and modified amino acid carriers
    Patent number: 9370492
    Abstract: The present invention provides novel solid pharmaceutical dosage forms for oral administration comprising a bisphosphonate, or a pharmaceutically acceptable salt thereof, which bisphosphonate is present in an amount not therapeutically effective when the bisphosphonate is orally administered alone, and a modified amino acid carrier, or a pharmaceutically acceptable salt thereof, which modified amino acid carrier is present in an amount effective to facilitate absorption of the bisphosphonate in the gastrointestinal tract such that the bisphosphonate is therapeutically effective. The ratio of bisphosphonate to modified amino acid carrier is from about 1:30 to about 1:1, respectively. These novel solid pharmaceutical dosage forms are useful in the treatment or control of bone diseases and particular disorders in calcium metabolism, including, for example, osteoporosis, hypercalcaemia of cancer, and the treatment of metastatic bone pain.
    Type: Grant
    Filed: July 16, 2009
    Date of Patent: June 21, 2016
    Assignee: EMISPHERE TECHNOLOGIES, INC.
    Inventors: Hashim Ahmed, Lewis Bender, Martin Howard Infeld, Shingai Majuru, Wantanee Phuapradit, Navnit Hargovindas Shah, Zhongshui Yu
  • Gallium nitrate formulations
    Patent number: 9364502
    Abstract: The present invention relates to stable pharmaceutical formulations that include a delivery agent and/or pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: June 14, 2016
    Assignee: EMISPHERE TECHNOLOGIES, INC.
    Inventors: Shingai Majuru, Moses O. Oyewumi, Mehmet Tahir Gurler
  • Crystalline polymorphic forms of monosodium N-[-8-(2-hydroxybenzoyl)amino]caprylate
    Patent number: 9321719
    Abstract: The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino]caprylate (“SNAC”), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: April 26, 2016
    Assignee: EMISPHERE TECHNOLOGIES, INC.
    Inventors: Halina Levchik, Shingai Majuru, Brahma Singh, Jamila Harris
  • SILK-BASED CAPSULES
    Publication number: 20160045443
    Abstract: A hard or soft capsule is disclosed comprising a shell and a fill material, wherein the shell comprises an interpenetrating network comprising a silk polymer and a film-forming natural polymer. A method of making a hard or soft capsule is also disclosed, comprising dissolving a silk protein in a solvent system to form a solubilized silk protein solution; mixing the solubilized silk protein solution with a film-forming natural polymer to form a homogenous shell material; and encapsulating a fill material with the homogenous shell material.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 18, 2016
    Inventors: Tatyana DYAKONOV, Derek BUSH, Saujanya L. GOSANGARI, Yang Hue CHUE, Shingai MAJURU, Aqeel FATMI