Patents by Inventor Shingo Iwashina

Shingo Iwashina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing 2-hydroxymethylmorpholine salt
    Patent number: 8648190
    Abstract: The invention relates to a production method of a 2-hydroxymethylmorpholine salt, which includes crystallization from a solution containing 2-hydroxymethylmorpholine of formula (1) 1,4-oxazepane compound of formula (2) and an acid.
    Type: Grant
    Filed: January 15, 2010
    Date of Patent: February 11, 2014
    Assignee: Daiso Co., Ltd.
    Inventors: Yoshifumi Nagano, Keisuke Yaegashi, Shingo Iwashina
  • PROCESS FOR PRODUCING 2-HYDROXYMETHYLMORPHOLINE SALT
    Publication number: 20120016120
    Abstract: The invention relates to a production method of a 2-hydroxymethylmorpholine salt, which includes crystallization from a solution containing 2-hydroxymethylmorpholine of formula (1) 1,4-oxazepane compound of formula (2) and an acid.
    Type: Application
    Filed: January 15, 2010
    Publication date: January 19, 2012
    Applicant: DAISO CO., LTD.
    Inventors: Yoshifumi Nagano, Keisuke Yaegashi, Shingo Iwashina
  • PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE COMPOUND
    Publication number: 20110288315
    Abstract: A 2-aryl-2-halomethyl-4-chloromethyl-1,3-dioxolane (A) can be produced conveniently without decreasing its optical purity by reacting an optically active monochlorohydrin and an aryl (halomethyl) ketone (starting materials) with each other in the presence of an acid catalyst. From the optically active compound (A) thus produced, an optically active carboxylic acid (2-aryl-2-halomethyl-1,3-dioxolan-4-yl)methyl ester and an optically active sulfonic acid (2-aryl-2-halomethyl-1,3-dioxolan-4-yl)methyl ester (both of which are useful intermediates for the production of ketoconazole) can be produced with good efficiency. An optically active trans-carboxylic acid (2-aryl-2-halomethyl-1,3-dioxolan-4-yl)methyl ester can be isomerized into its cis-form in the presence of an acid catalyst.
    Type: Application
    Filed: March 23, 2009
    Publication date: November 24, 2011
    Applicant: DAISO CO., LTD.
    Inventors: Yutaka Ishii, Shingo Iwashina, Takahiro Kawase, Yumiko Matsui