Abstract: A method of increasing expression of the aromatase gene by treating a cell population with an effective amount of an aromatase activator containing an extract of Iris florentina, where the effective amount ranges from 0.0001 to 1% by weight based on the total weight of the aromatase activator on a dry basis.

Abstract: Provided is a material safely promoting the production of estrogen in a living body. The invention relates to use of a compound represented by the following formula (I) or a solvate thereof for producing an aromatase activator. The invention relates to an aromatase activation method comprising administering a compound represented by the following formula (I) or a solvate thereof (wherein the dashed line indicates that the bond may be a double bond, provided that a and b in the formula (I) do not simultaneously represent a double bond).

Abstract: Provided is a material safely promoting the production of estrogen in a living body. The invention relates to use of a compound represented by the following formula (I) or a solvate thereof for producing an aromatase activator. The invention relates to an aromatase activation method comprising administering a compound represented by the following formula (I) or a solvate thereof (wherein the dashed line indicates that the bond may be a double bond, provided that a and b in the formula (I) do not simultaneously represent a double bond).

Abstract: The level of a steroid hormone, including estrogen, in the stratum corneum of the skin is assayed by LC-MS analysis of a steroid hormone in the stratum corneum of the skin collected by a tape stripping method. This allows the concentration in the skin of the steroid hormone, including estrogen which has an important effect on the state of the skin, to be easily measured.

Abstract: A method of increasing expression of the aromatase gene by treating a cell population with an effective amount of an aromatase activator containing an extract of Iris florentina, where the effective amount ranges from 0.0001 to 1% by weight based on the total weight of the aromatase activator on a dry basis.

Abstract: Drugs and cosmetics which are highly safe, and which are effective in preventing, improving, or treating various pathological conditions caused by estrogen depletion are provided. Provided are aromatase activators containing at least one member selected from plants such as Labiatae sps. including Isodon, Scutellaria (huangcen), Schizonepeta (jingjie), sage, lavender, Lamium album, and thyme, an extract thereof; yeast extract; silk protein extract; milk protein; trehalose; natto extract; royal jelly; oryza oil; hydrolyzated wheat extract; shea butter; and rice fermentation extract.

Abstract: The level of a steroid hormone, including estrogen, in the stratum corneum of the skin is assayed by LC-MS analysis of a steroid hormone in the stratum corneum of the skin collected by a tape stripping method. This allows the concentration in the skin of the steroid hormone, including estrogen which has an important effect on the state of the skin, to be easily measured.

Abstract: The present invention is directed to an aromatase activating agent containing a plant selected from among mulberry bark, ginseng, cucumber, and phellodendron bark; or chlorella; or an extract of any of these ingredients. The aromatase activating agent of the present invention is highly safe to the human body, and useful as a drug or cosmetic composition for prevention, amelioration, or treatment of various lesions caused by estrogen deficiency.

Abstract: The present invention is directed to an aromatase activating agent containing a plant selected from among mulberry bark, ginseng, cucumber, and phellodendron bark; or chlorella; or an extract of any of these ingredients. The aromatase activating agent of the present invention is highly safe to the human body, and useful as a drug or cosmetic composition for prevention, amelioration, or treatment of various lesions caused by estrogen deficiency.

Abstract: Drugs and cosmetics which are highly safe, and which are effective in preventing, improving, or treating various pathological conditions caused by estrogen depletion are provided. Provided are aromatase activators containing at least one member selected from plants such as Labiatae sps. including Isodon, Scutellaria (huangcen), Schizonepeta (jingjie), sage, lavender, Lamium album, and thyme, an extract thereof; yeast extract; silk protein extract; milk protein; trehalose; natto extract; royal jelly; oryza oil; hydrolyzated wheat extract; shea butter; and rice fermentation extract.

Abstract: The present invention is directed to an aromatase activating agent containing a plant selected from among mulberry bark, ginseng, cucumber, and phellodendron bark; or chlorella; or an extract of any of these ingredients. The aromatase activating agent of the present invention is highly safe to the human body, and useful as a drug or cosmetic composition for prevention, amelioration, or treatment of various lesions caused by estrogen deficiency.