Patents by Inventor Shingo Nakahata

Shingo Nakahata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphorylation-inhibiting agent or dephosphorylating agent for PTEN
    Patent number: 9023343
    Abstract: Provided is a preventive, progression inhibitor or remedy for a disease one of the causes of which is the activation of the P13K/AKT signaling pathway or vice versa. A phosphorylation-inhibiting and/or dephosphorylating agent, which has an effect of inhibiting the phosphorylation at least at one of the phosphorylation sites of PTEN protein selected from the group consisting of T382, T383 and S380 and/or an effect of dephosphorylating the same, is prepared. Alternatively, a phosphorylation-inhibiting or dephosphorylating agent for PTEN is screened by a method comprising a step for confirming an ability of a test substance to inhibit the phosphorylation at least at one of the phosphorylation sites of PTEN protein selected from the group consisting of T382, T383 and S380 or a dephosphorylation ability thereof. Then, a substance having an effect opposite to the inhibition of PTEN phosphorylation or dephosphorylation thereof, e.g.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: May 5, 2015
    Assignee: Miyazaki Prefecture
    Inventors: Kazuhiro Morishita, Shingo Nakahata, Makoto Hamasaki
  • PHOSPHORYLATION-INHIBITING AGENT OR DEPHOSPHORYLATING AGENT FOR PTEN
    Publication number: 20120107299
    Abstract: Provided is a preventive, progression inhibitor or remedy for a disease one of the causes of which is the activation of the P13K/AKT signaling pathway or vice versa. A phosphorylation-inhibiting and/or dephosphorylating agent, which has an effect of inhibiting the phosphorylation at least at one of the phosphorylation sites of PTEN protein selected from the group consisting of T382, T383 and S380 and/or an effect of dephosphorylating the same, is prepared. Alternatively, a phosphorylation-inhibiting or dephosphorylating agent for PTEN is screened by a method comprising a step for confirming an ability of a test substance to inhibit the phosphorylation at least at one of the phosphorylation sites of PTEN protein selected from the group consisting of T382, T383 and S380 or a dephosphorylation ability thereof. Then, a substance having an effect opposite to the inhibition of PTEN phosphorylation or dephosphorylation thereof, e.g.
    Type: Application
    Filed: March 26, 2010
    Publication date: May 3, 2012
    Applicants: MIYAZAKI PREFECTURAL INDUSTRIAL SUPPORT FOUNDATION, UNIVERSITY OF MIYAZAKI
    Inventors: Kazuhiro Morishita, Shingo Nakahata, Makoto Hamasaki