Abstract: Disclosed is an immunity-inducing agent having excellent ease of production and high immunostimulatory activity, the immunity-inducing agent comprising, as an active component, a polynucleotide/peptide conjugate in which an antigenic peptide is covalently bound to a single-stranded polynucleotide or polynucleotide derivative. Also disclosed is a pharmaceutical composition comprising said immunity-inducing agent.

Abstract: A main bearing for a journal portion of a crankshaft includes a pair of upper and lower half bearings forming a cylindrical shape. Each half bearing includes a main cylindrical portion including a circumferentially central portion and having a slide surface, and crush reliefs formed on both circumferential sides of the slide surface. Only the upper half bearing includes an oil groove on its inner peripheral surface, and an oil hole pierced from the oil groove to an outer peripheral surface. The lower half bearing includes an axial groove on the slide surface that is arranged apart from the circumferentially central portion toward the forward side by a circumferential angle of 10° or more, and apart from the crush relief located on the forward side by a circumferential angle of 10° or more.

Abstract: A connecting rod bearing for a crankpin of a crankshaft of an internal combustion engine includes a pair of half bearings forming a cylindrical shape. Each half bearing has a main cylindrical portion including a circumferentially central portion of the half bearing, and crush reliefs formed on both circumferential sides of the main cylindrical portion with a wall thickness being smaller than that of the main cylindrical portion. At least one half bearing has an axial groove which extends in an axial direction on a slide surface of the main cylindrical portion, and is apart from the circumferentially central portion by a circumferential angle of 10° or more toward a forward side in a rotation direction of the crankpin, and apart from the crush relief by a circumferential angle of 10° or more toward the circumferentially central portion.

Abstract: Provided is a semi-cylindrical-shaped half bearing having an inner surface including a center zone and end zones each including a plurality of recesses. Each recess includes a groove forming zone adjacent to the peripheral edge and including a plurality of circumferential grooves extending from the peripheral edge along the circumferential direction. An area ratio S2 of an area of the groove forming zone to an area of the recess in the end zone is larger than an area ratio S1 in the center zone. A maximum depth D4 of the circumferential groove in the end zone is larger than a maximum depth D2 of the circumferential groove in the center zone. A sliding bearing of the present invention includes the above half bearing.

Abstract: A half thrust bearing includes a sliding surface for receiving an axial force of a crankshaft of an engine, and a rear surface on an opposite side thereto. The sliding surface includes a flat surface portion near a circumferentially central portion, and two inclined flat surface portions on both circumferential sides of the flat surface portion. The axial distance between the rear surface and the sliding surface is maximum at the flat surface portion. At any radial positions, the axial distance in each inclined flat surface portion is maximum on a circumferentially central portion side and is reduced toward a circumferential end portion of the half thrust bearing. Each inclined flat surface portion is arranged to form one constant thickness portion extending linearly from a radially inner end to a radially outer end at a circumferential angle of 45°.

Abstract: Provided is a semi-cylindrical shaped half bearing. The half bearing has an inner surface forming a sliding surface and including a plurality of recesses. Each recess has a smooth recess surface and a peripheral edge. The recess surface forms a convex curve toward the outer diameter side of the half bearing in cross-sectional view in a direction parallel to a circumferential direction of the half bearing. The recess includes a groove forming zone adjacent to the peripheral edge of the recess. The groove forming zone includes a plurality of circumferential grooves. The circumferential grooves extend from the peripheral edge of the recess along the circumferential direction of the half bearing. The present invention also provides a cylindrical sliding bearing including the above half bearing.

Abstract: Provided is a semi-cylindrical-shaped half bearing having an inner surface including a center zone and end zones each including a plurality of recesses. Each recess includes a groove forming zone adjacent to the peripheral edge and including a plurality of circumferential grooves extending from the peripheral edge along the circumferential direction. An area ratio S2 of an area of the groove forming zone to an area of the recess in the end zone is larger than an area ratio S1 in the center zone. A maximum depth D4 of the circumferential groove in the end zone is larger than a maximum depth D2 of the circumferential groove in the center zone. A sliding bearing of the present invention includes the above half bearing.

Abstract: A connecting rod bearing for a crankpin of a crankshaft of an internal combustion engine includes a pair of half bearings forming a cylindrical shape. Each half bearing has a main cylindrical portion including a circumferentially central portion of the half bearing, and crush reliefs formed on both circumferential sides of the main cylindrical portion with a wall thickness being smaller than that of the main cylindrical portion. At least one half bearing has an axial groove which extends in an axial direction on a slide surface of the main cylindrical portion, and is apart from the circumferentially central portion by a circumferential angle of 10° or more toward a forward side in a rotation direction of the crankpin, and apart from the crush relief by a circumferential angle of 10° or more toward the circumferentially central portion.

Abstract: A main bearing for a journal portion of a crankshaft includes a pair of upper and lower half bearings forming a cylindrical shape. Each half bearing includes a main cylindrical portion including a circumferentially central portion and having a slide surface, and crush reliefs formed on both circumferential sides of the slide surface. Only the upper half bearing includes an oil groove on its inner peripheral surface, and an oil hole pierced from the oil groove to an outer peripheral surface. The lower half bearing includes an axial groove on the slide surface that is arranged apart from the circumferentially central portion toward the forward side by a circumferential angle of 10° or more, and apart from the crush relief located on the forward side by a circumferential angle of 10° or more.

Abstract: A half thrust bearing having a semi-annular shape includes a sliding surface for receiving an axial force of a crankshaft of an internal combustion engine, and a rear surface on an opposite side of the sliding surface, and defines a reference plane on the rear surface side that is perpendicular to an axial direction. The sliding surface includes a flat surface portion near a circumferentially central portion and in parallel with the reference plane, and inclined surface portions on both sides of the flat surface portion in a circumferential direction. At any radial positions of the half thrust bearing, an axial distance between the reference plane and the sliding surface is maximum at the flat surface portion, and is reduced in the inclined surface portions toward both circumferential end portions of the half thrust bearing.

Abstract: Provided is a semi-cylindrical shaped half bearing. The half bearing has an inner surface forming a sliding surface and including a plurality of recesses. Each recess has a smooth recess surface and a peripheral edge. The recess surface forms a convex curve toward the outer diameter side of the half bearing in cross-sectional view in a direction parallel to a circumferential direction of the half bearing. The recess includes a groove forming zone adjacent to the peripheral edge of the recess. The groove forming zone includes a plurality of circumferential grooves. The circumferential grooves extend from the peripheral edge of the recess along the circumferential direction of the half bearing. The present invention also provides a cylindrical sliding bearing including the above half bearing.

Abstract: A half thrust bearing includes a sliding surface for receiving an axial force of a crankshaft of an engine, and a rear surface on an opposite side thereto. The sliding surface includes a flat surface portion near a circumferentially central portion, and two inclined flat surface portions on both circumferential sides of the flat surface portion. The axial distance between the rear surface and the sliding surface is maximum at the flat surface portion. At any radial positions, the axial distance in each inclined flat surface portion is maximum on a circumferentially central portion side and is reduced toward a circumferential end portion of the half thrust bearing. Each inclined flat surface portion is arranged to form one constant thickness portion extending linearly from a radially inner end to a radially outer end at a circumferential angle of 45°.

Abstract: A half thrust bearing having a semi-annular shape includes a sliding surface for receiving an axial force of a crankshaft of an internal combustion engine, and a rear surface on an opposite side of the sliding surface, and defines a reference plane on the rear surface side that is perpendicular to an axial direction. The sliding surface includes a flat surface portion near a circumferentially central portion and in parallel with the reference plane, and inclined surface portions on both sides of the flat surface portion in a circumferential direction. At any radial positions of the half thrust bearing, an axial distance between the reference plane and the sliding surface is maximum at the flat surface portion, and is reduced in the inclined surface portions toward both circumferential end portions of the half thrust bearing.

Abstract: A method for manufacturing an insulator for a spark plug is provided. The method includes: a preparing step; a press pin arranging step; a powder filling step after the press pin arranging step; a cavity blocking step after the powder filling step; a compression molding step after the cavity blocking step; a die releasing step after the compression molding step; and a press pin removing step after the die releasing step.

Abstract: A method for manufacturing an insulator for a spark plug is provided. The method includes: a preparing step; a press pin arranging step; a powder filling step after the press pin arranging step; a cavity blocking step after the powder filling step; a compression molding step after the cavity blocking step; a die releasing step after the compression molding step; and a press pin removing step after the die releasing step.

Abstract: A methacrylic acid ester composition comprising 10 to 50 parts by weight of a cross-linked acrylic acid ester elastomer (A) and 50 to 90 parts by weight of a resin component, the total amount of the elastomer (A) and the resin component being 100 parts by weight; which is prepared by(a) preparing the cross-linked acrylic acid ester elastomer (A) by emulsion-polymerization,(b) adding a monomer component (B) to the elastomer (A) in the emulsion, and(c) polymerizing a monomer mixture (2) in the presence of the elastomer (A) to give the resin component.The composition is excellent in the processibility and can provide the film having the excellent transparency, weatherability, flexbility and whitening resistance to hot water.