Abstract: A mechanical seal device in which, between a processing equipment which performs processing under a sterile condition and a rotary shaft used with its one end inserted in the processing equipment from an atmosphere side, seal parts are disposed outside the processing equipment at least at two places along a length direction of the rotary shaft from the processing equipment side toward the atmosphere side seals the rotary shaft, and when the inside of the processing equipment and the seal parts are sterilized, the atmosphere-side seal part is also easily and surely sterilized similarly to the other seal part.

Abstract: A mechanical seal device in which, between a processing equipment which performs processing under a sterile condition and a rotary shaft used with its one end inserted in the processing equipment from an atmosphere side, seal parts are disposed outside the processing equipment at least at two places along a length direction of the rotary shaft from the processing equipment side toward the atmosphere side seals the rotary shaft, and when the inside of the processing equipment and the seal parts are sterilized, the atmosphere-side seal part is also easily and surely sterilized similarly to the other seal part.

Abstract: A method for evaluating the powder dispersibility including dispersing a powder allowed to stand inside a closed container by mechanical vibration applied quantitatively to the powder; collecting the dispersed powder on a quartz crystal element or a piezo element; and measuring the mass of the collected powder using a quartz crystal microbalance or a piezo element mass meter to thereby measure the airborne powder concentration in air inside the closed container; a method for evaluating airborne powder concentration at work place using the method for evaluating the powder dispersibility; and a method for designing a powder containment facility using the method for evaluating airborne powder concentration.

Abstract: A method for evaluating the powder dispersibility including dispersing a powder allowed to stand inside a closed container by mechanical vibration applied quantitatively to the powder; collecting the dispersed powder on a quartz crystal element or a piezo element; and measuring the mass of the collected powder using a quartz crystal microbalance or a piezo element mass meter to thereby measure the airborne powder concentration in air inside the closed container; a method for evaluating airborne powder concentration at work place using the method for evaluating the powder dispersibility; and a method for designing a powder containment facility using the method for evaluating airborne powder concentration.