Abstract: The present invention provides a zirconia pre-sintered body that can be fired into a sintered body having translucency and strength suited for dental use (particularly, at the dental clinic), even with a short firing time. The present invention relates to a zirconia pre-sintered body comprising: zirconia; and a stabilizer capable of inhibiting a phase transformation of zirconia, wherein the zirconia predominantly comprises a monoclinic crystal system, and the zirconia pre-sintered body comprises a plurality of layers that differ from each other in the content of the stabilizer relative to the total mole of the zirconia and the stabilizer.

Abstract: The invention provides antibodies that specifically bind to OX40 (CD134), referred to as OX40 antibodies, anti-OX40 or anti-OX40 antibodies. Invention antibodies that specifically bind to OX40 include mammalian (human, primate, etc.), humanized and chimeric anti-OX40 antibodies. Invention antibodies and antibody subsequences (fragments) that specifically bind to OX40 include purified and isolated antibodies, as well as pharmaceutical formulations thereof, are useful in various methods including treatment, screening and detection methods.

Abstract: The present invention provides a zirconia pre-sintered body that develops the preferable shade with a short firing time.

Abstract: A controller includes at least one processor that implements the instructions to execute a plurality of tasks. The plurality of tasks includes a management table obtaining task that obtains, from the management table including first information indicating a region and second information indicating a country or a region, a destination information obtaining task that obtains third information indicating a region of a shipping destination to which the terminal device is to be shipped, a first specifying task that specifies a first function, a determining task that determines whether a second function, with reference to the second information, needs to be specified, an estimation information obtaining task that in a case where the second function is determined to be necessary, obtains estimation information corresponding to the second information from an external device, and a second specifying task that specifies the second function.

Abstract: A mobile device for an authentication system that performs authentication to control an authentication target with code verification via near field wireless communication, includes: an acceleration sensor; a communication portion that performs the near field wireless communication with an antenna of the authentication target; a reception stop portion that stops reception operation of the communication portion; a fault detection portion that detects a failure in the acceleration sensor; and an operation change portion that prevents the reception stop portion from stopping the reception operation.

Abstract: A control apparatus can include a network interface that achieves a connection to a network, a user interface that accepts a selection operation from among images displayed on a display portion, and at least one processor that implements stored instructions to execute a plurality of tasks, which can include a control task, a designation task, and a display control task. The control task is configured to, through the network, control a plurality of external devices that transmit or receive content data. The designation task is configured to designate an image to display on the display portion. The display control task is configured to display, for each of the plurality of external devices, an image relating to the respective external device on the display portion. The display control task changes an image selected through the user interface to the image designated by the designation task.

Abstract: A control terminal device includes a display, at least one processor, and a memory configured to store instructions, when executed by the at least one processor, cause the control terminal device to transmit command messages to the plurality of communication devices disposed in respective areas and connected via a network, and to display on the display an operation screen, a device selection screen for selecting any one of the plurality of communication devices, and area images indicating the areas in which the respective communication devices are disposed so as to serve as a selection operation section for selecting the respective communication devices.

Abstract: A front wheel caliper bracket for supporting an axle is provided in a lower end portion of a front fork. A wheel speed sensor is mounted on the bracket. The wheel speed sensor includes a fixing section and a sensor section, and is mounted on a sensor mounting section of the bracket by a bolt. The sensor mounting section is integrally formed with a rotation regulating portion in a projecting fashion. When fastened by the bolt, a lateral part of the rotating wheel speed sensor comes into contact with the rotation regulating portion to regulate the rotation of the wheel speed sensor, so that the stress from the rotation regulating portion is not exerted directly on the sensor section.

Abstract: This disclosure provides compositions and methods of treating cancer by inhibiting histone methyltransferases alone or in combination by synergistically inhibiting a histone demethylase, or a histone deacetylase (HDAC), or a bromodomain (BRD)-containing protein, or a B-Raf kinase. In particular, the cancers have deficient of SWUSNF chromatin remodeling complexes because of mutations in one or more of the complex's subunit members.

Abstract: The invention provides antibodies that specifically bind to OX40 (CD134), referred to as OX40 antibodies, anti-OX40 or anti-OX40 antibodies. Invention antibodies that specifically bind to OX40 include mammalian (human, primate, etc.), humanized and chimeric anti-OX40 antibodies. Invention antibodies and antibody subsequences (fragments) that specifically bind to OX40 include purified and isolated antibodies, as well as pharmaceutical formulations thereof, are useful in various methods including treatment, screening and detection methods.

Abstract: A control apparatus can include a network interface that achieves a connection to a network, a user interface that accepts a selection operation from among images displayed on a display portion, and at least one processor that implements stored instructions to execute a plurality of tasks, which can include a control task, a designation task, and a display control task. The control task is configured to, through the network, control a plurality of external devices that transmit or receive content data. The designation task is configured to designate an image to display on the display portion. The display control task is configured to display, for each of the plurality of external devices, an image relating to the respective external device on the display portion. The display control task changes an image selected through the user interface to the image designated by the designation task.

Abstract: The invention provides antibodies that specifically bind to OX40 (CD134), referred to as OX40 antibodies, anti-OX40 or anti-OX40 antibodies. Invention antibodies that specifically bind to OX40 include mammalian (human, primate, etc.), humanized and chimeric anti-OX40 antibodies. Invention antibodies and antibody subsequences (fragments) that specifically bind to OX40 include purified and isolated antibodies, as well as pharmaceutical formulations thereof, are useful in various methods including treatment, screening and detection methods.

Abstract: A front wheel caliper bracket for supporting an axle is provided in a lower end portion of a front fork. A wheel speed sensor is mounted on the bracket. The wheel speed sensor includes a fixing section and a sensor section, and is mounted on a sensor mounting section of the bracket by a bolt. The sensor mounting section is integrally formed with a rotation regulating portion in a projecting fashion. When fastened by the bolt, a lateral part of the rotating wheel speed sensor comes into contact with the rotation regulating portion to regulate the rotation of the wheel speed sensor, so that the stress from the rotation regulating portion is not exerted directly on the sensor section.

Abstract: A control terminal device includes a display, at least one processor, and a memory configured to store instructions, when executed by the at least one processor, cause the control terminal device to transmit command messages to the plurality of communication devices disposed in respective areas and connected via a network, and to display on the display an operation screen, a device selection screen for selecting any one of the plurality of communication devices, and area images indicating the areas in which the respective communication devices are disposed so as to serve as a selection operation section for selecting the respective communication devices.

Abstract: In a vehicle including a pulse ring that rotates together with a wheel, a wheel speed sensor that has a detection portion close to the pulse ring, and a bracket that fixes the wheel speed sensor, a tubular protective wall surrounding the detection portion is provided on the bracket so that an end part, on the pulse ring side, of the protective wall is closer to the pulse ring than the detection portion of the wheel speed sensor is. This enables the wheel speed sensor to be protected without adding a special component.

Abstract: Provided herein are antibodies that immunospecifically bind to an hLIGHT polypeptide; isolated nucleic acids encoding the antibodies; vectors and host cells comprising nucleic acids encoding the antibodies; methods of making the antibodies; and a method of treating a hLIGHT-mediated disease in a subject comprising administering to the subject the antibodies. In preferred embodiments, the anti-hLIGHT antibodies provided herein will ameliorate, neutralize or otherwise inhibit hLIGHT biological activity in vivo (e.g., the hLIGHT-mediated production or secretion of CCL20, IL-8 or RANTES from a cell expressing a hLIGHT receptor). Also provided herein is a method for the detection of hLIGHT in a sample as well as a method for ameliorating, neutralizing or otherwise inhibiting hLIGHT activity, e.g., in a human subject suffering from a disorder in which hLIGHT activity is detrimental.

Abstract: The invention provides a carburized part which has excellent medium-cycle fatigue strength in particular subjected to surface-hardening treatment by carburization. The invention provides a carburized part including a carburized layer formed by performing carburizing treatment to a steel, the steel including, in terms of % by mass: 0.15% to 0.25% of C, 0.15% or less of Si, 0.4% to 1.1% of Mn, 0.8% to 1.4% of Cr, 0.25% to 0.55% of Mo, 0.015% or less of P, and 0.035% or less of S, with the remainder being Fe and unavoidable impurities, and the steel satisfying the following relation; 0.10?[Mo]/(10[Si]+[Mn]+[Cr])?0.40, in which [M] represents a content of element M in terms of % by mass.

Abstract: The invention provides antibodies that specifically bind to OX40 (CD134), referred to as OX40 antibodies, anti-OX40 or anti-OX40 antibodies. Invention antibodies that specifically bind to OX40 include mammalian (human, primate, etc.), humanized and chimeric anti-OX40 antibodies. Invention antibodies and antibody subsequences (fragments) that specifically bind to OX40 include purified and isolated antibodies, as well as pharmaceutical formulations thereof, are useful in various methods including treatment, screening and detection methods.

Abstract: Provided is a method of manufacturing a nitrocarburized crankshaft which is obtained by subjecting a bainitic microalloyed steel to a forging and a machining, and further subjecting the bainitic microalloyed steel to at least a strain releasing heat treatment and a subsequent nitrocarburizing treatment, the bainitic microalloyed steel containing, as essentially added elements, in terms of mass %: 0.10% to 0.40% of C; 0.10% to 1.0% of Si; 1.0% to 2.0% of Mn; 0.05% to 0.40% of Mo; and 0.05% to 0.40% of V, and the bainitic microalloyed steel optionally further containing, as arbitrarily added elements, in terms of mass %: 0.01% to 0.1% of S; 0.005% to 0.2% of Ti; 0.001% to 0.03% of Al; 0.50% or less of Cr; 0.5% or less of Cu; and 0.5% or less of Ni, with the balance being Fe and unavoidable impurities.

Abstract: The invention provides antibodies that specifically bind to OX40 (CD134), referred to as OX40 antibodies, anti-OX40 or anti-OX40 antibodies. Invention antibodies that specifically bind to OX40 include mammalian (human, primate, etc.), humanized and chimeric anti-OX40 antibodies. Invention antibodies and antibody subsequences (fragments) that specifically bind to OX40 include purified and isolated antibodies, as well as pharmaceutical formulations thereof, are useful in various methods including treatment, screening and detection methods.