Patents by Inventor Shinichiro Ogawa

Shinichiro Ogawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF MAKING AND USING LIVER CELLS
    Publication number: 20220233605
    Abstract: Provided herein are methods of making and using a number of different types of liver cells.
    Type: Application
    Filed: June 3, 2020
    Publication date: July 28, 2022
    Inventors: Shinichiro Ogawa, Mina Ogawa, Gordon Keller
  • METHODS FOR GENERATING HEPATOCYTES AND CHOLANGIOCYTES FROM PLURIPOTENT STEM CELLS
    Publication number: 20200157494
    Abstract: Methods for producing hepatocyte and/or cholangiocyte lineage cells from pluripotent stem cells, the method comprising (a) specifying the extended nodal agonist treated induced endodermal cell population to obtain a cell population comprising hepatocyte and/or cholangiocyte progenitors by contacting the extended nodal agonist treated induced endodermal cell population with specification media comprising a FGF agonist and a BMP4 agonist and/or active conjugates and/or fragments thereof; (b) inducing maturation, and optionally further lineage specification and/or expansion of the hepatocyte and/or cholangiocyte progenitors of the cell population to obtain a population comprising hepatocyte lineage cells such as hepatoblasts, hepatocytes and/or cholangiocytes, the inducing maturation step comprising generating aggregates of the cell population. Optionally, the method also comprises activating the cAMP pathway within the aggregates and forming co-aggregates.
    Type: Application
    Filed: August 22, 2018
    Publication date: May 21, 2020
    Applicants: UNIVERSITY HEALTH NETWORK, THE HOSPITAL FOR SICK CHILDREN
    Inventors: Gordon KELLER, Shinichiro OGAWA, Anand GHANEKAR, Christine BEAR, Binita M. KAMATH, Mina OGAWA, James SURAPISITCHAT
  • METHODS FOR GENERATING HEPATOCYTES AND CHOLANGIOCYTES FROM PLURIPOTENT STEM CELLS
    Publication number: 20160002595
    Abstract: Methods for producing hepatocyte and/or cholangiocyte lineage cells from pluripotent stem cells, the method comprising (a) specifying the extended nodal agonist treated induced endodermal cell population to obtain a cell population comprising hepatocyte and/or cholangiocyte progenitors by contacting the extended nodal agonist treated induced endodermal cell population with specification media comprising a FGF agonist and a BMP4 agonist and/or active conjugates and/or fragments thereof; (b) inducing maturation, and optionally further lineage specification and/or expansion of the hepatocyte and/or cholangiocyte progenitors of the cell population to obtain a population comprising hepatocyte lineage cells such as hepatoblasts, hepatocytes and/or cholangiocytes, the inducing maturation step comprising generating aggregates of the cell population. Optionally, the method also comprises activating the cAMP pathway within the aggregates and forming co-aggregates.
    Type: Application
    Filed: February 18, 2014
    Publication date: January 7, 2016
    Inventors: Gordon KELLER, Shinichiro OGAWA, Anand GHANEKAR, Christine BEAR, Binita M. KAMATH, Mina OGAWA, James SURAPISITCHAT
  • Triketone derivatives and herbicide
    Patent number: 6756343
    Abstract: The present invention relates to a novel triketone derivative having a specific structure and a herbicide containing the triketone derivative as an active ingredient. The herbicide is effective for controlling weeds which inhibit growth of crop plants, inter alia, for paddy weeds such as Sanwa millet and Scirups juncoides.
    Type: Grant
    Filed: April 23, 2001
    Date of Patent: June 29, 2004
    Assignee: Idemitsu Kosan Co., Ltd.
    Inventors: Masatoshi Saitou, Hiroki Sekiguchi, Shinichiro Ogawa
  • Triketone derivatives and herbicides
    Publication number: 20040002425
    Abstract: The present invention relates to a novel triketone derivative having a specific structure and a herbicide containing the triketone derivative as an active ingredient. The herbicide is effective for controlling weeds which inhibit growth of crop plants, inter alia, for paddy weeds such as Sanwa millet and Scirups juncoides.
    Type: Application
    Filed: April 1, 2003
    Publication date: January 1, 2004
    Applicant: Idemitsu Kosan Co., Ltd.
    Inventors: Masatoshi Saitou, Hiroki Sekiguchi, Shinichiro Ogawa