Patents by Inventor Shinichiro Oida

Shinichiro Oida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Effect of porcine sheath proteins on the regeneration activity of periodontal ligament
    Patent number: 8309140
    Abstract: The purpose of this study was to identify the periodontal regeneration factors in enamel protein shown to induce cementum- and osteo-promotive activities in vivo. The cementum regeneration (CR), a part of periodontal regeneration, was examined by using experimental cavities prepared in a buccal dehiscence dog model. The CR activity was found in the aggregate consisted of sheath proteins along with a small amount of amelogenins separated from newly formed secretory enamel. The sheath proteins were purified to be homogeneous, and examined for the alkaline phosphatase (ALP) inducing activity of human periodontal ligament (HPDL) cells. Application of 17 kDa sheath protein induced ALP activity in HPDL cells. Peptides synthesized from the sheath protein sequence also showed ALP inducing activity. The 17 kDa sheath protein has cell differentiation activity.
    Type: Grant
    Filed: April 19, 2010
    Date of Patent: November 13, 2012
    Inventors: Makoto Fukae, Kazuhiro Gomi, Mikimoto Kanazashi, Shinichiro Oida, Ayako Kakegawa
  • Effect of Porcine Sheath Proteins on the Regeneration Activity of Periodontal Ligament
    Publication number: 20100227820
    Abstract: The purpose of this study was to identify the periodontal regeneration factors in enamel protein shown to induce cementum- and osteo-promotive activities in vivo. The cementum regeneration (CR), a part of periodontal regeneration, was examined by using experimental cavities prepared in a buccal dehiscence dog model. The CR activity was found in the aggregate consisted of sheath proteins along with a small amount of amelogenins separated from newly formed secretory enamel. The sheath proteins were purified to be homogeneous, and examined for the alkaline phosphatase (ALP) inducing activity of human periodontal ligament (HPDL) cells. Application of 17 kDa sheath protein induced ALP activity in HPDL cells. Peptides synthesized from the sheath protein sequence also showed ALP inducing activity. The 17 kDa sheath protein has cell differentiation activity.
    Type: Application
    Filed: April 19, 2010
    Publication date: September 9, 2010
    Inventors: Makoto FUKAE, Kazuhiro GOMI, Mikimoto KANAZASHI, Shinichiro OIDA, Ayako KAKEGAWA
  • Effect of porcine sheath proteins on the regeneration activity of periodontal ligament
    Patent number: 7722900
    Abstract: The purpose of this study was to identify the periodontal regeneration factors in enamel protein shown to induce cementum- and osteo-promotive activities in vivo. The cementum regeneration (CR), a part of periodontal regeneration, was examined by using experimental cavities prepared in a buccal dehiscence dog model. The CR activity was found in the aggregate consisted of sheath proteins along with a small amount of amelogenins separated from newly formed secretory enamel. The sheath proteins were purified to be homogeneous, and examined for the alkaline phosphatase (ALP) inducing activity of human periodontal ligament (HPDL) cells. Application of 17 kDa sheath protein induced ALP activity in HPDL cells. Peptides synthesized from the sheath protein sequence also showed ALP inducing activity. The 17 kDa sheath protein has cell differentiation activity.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: May 25, 2010
    Inventors: Makoto Fukae, Kazuhiro Gomi, Mikimoto Kanazashi, Shinichiro Oida, Takatoshi Nagano, Takako Tanabe, Yukiko Tanabe, legal representative, Ayako Kakegawa
  • Effect of porcine sheath proteins on the regeneration activity of periodontal ligament
    Publication number: 20060280699
    Abstract: The purpose of this study was to identify the periodontal regeneration factors in enamel protein shown to induce cementum- and osteo-promotive activities in vivo. The cementum regeneration (CR), a part of periodontal regeneration, was examined by using experimental cavities prepared in a buccal dehiscence dog model. The CR activity was found in the aggregate consisted of sheath proteins along with a small amount of amelogenins separated from newly formed secretory enamel. The sheath proteins were purified to be homogeneous, and examined for the alkaline phosphatase (ALP) inducing activity of human periodontal ligament (HPDL) cells. Application of 17 kDa sheath protein induced ALP activity in HPDL cells. Peptides synthesized from the sheath protein sequence also showed ALP inducing activity. The 17 kDa sheath protein has cell differentiation activity.
    Type: Application
    Filed: April 6, 2006
    Publication date: December 14, 2006
    Inventors: Makoto Fukae, Kazuhiro Gomi, Mikimoto Kanazashi, Shinichiro Oida, Takatoshi Nagano, Takako Tanabe, Yukiko Tanabe, Ayako Kakegawa