Abstract: New use of ADAMTS13 in the clinical filed is provided. The use of ADAMTS13 as a biomarker for monitoring the onset of liver damage, hepatic ischemia/reperfusion injury or the liver function after liver transplantation: a method of testing liver damage, a method of testing hepatic ischemia/reperfusion injury, or a method of testing the liver function after liver transplantation, each of the methods comprising measuring or monitoring the ADAMTS13 activity in a sample from a mammal; an agent for treating diseases selected from the group consisting of liver damage, hepatic ischemia/reperfusion injury and hepatic dysfunction after liver transplantation, which comprises ADAMTS13 or a mutant of ADAMTS13 as an effective ingredient.

Abstract: A terminal operated by a user is connected to a server group, including a management server, a mail server, and a database server, via the Internet. In the database server, current account information, including a mail address of the user for mail exchange is registered. When the user registers a new mail address in the terminal, the new mail address is notified to the mail server and the database server. The database server updates the registered account information and also updates the account information registered in the mail server. The update of the account information in the server group is notified to the terminal. When the update of the account information is notified, the terminal apparatus requests the database server to send the account information. The terminal internally registers the account information sent from the database server in response to the request.

Abstract: A standard mail address is assigned to each user who uses mail exchange service provided by a mail server. Each user can also have an extended mail address including a character name used in a network game provided by a game server. The extended mail address can be changed/deleted by user selection. When generating a return mail, a sender address of an original mail which is received from the mail server, is set to a destination address of the return mail. A destination address of the original mail is set to a sender address of the return mail when the destination address is currently available. When the destination address of the original mail is currently unavailable, the standard mail address is set to the sender address of the return mail.

Abstract: A terminal operated by a user is connected to a server group, including a management server, a mail server, and a database server, via the Internet. In the database server, current account information, including a mail address of the user for mail exchange is registered. When the user registers a new mail address in the terminal, the new mail address is notified to the mail server and the database server. The database server updates the registered account information and also updates the account information registered in the mail server. The update of the account information in the server group is notified to the terminal. When the update of the account information is notified, the terminal apparatus requests the database server to send the account information. The terminal internally registers the account information sent from the database server in response to the request.