Patents by Inventor Shinji Hourai

Shinji Hourai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Asymmetric hydrolase and gene thereof
    Patent number: 8691548
    Abstract: The present invention relates to, for example, an ?-substituted ?-amino acid ester derivative asymmetric hydrolase including an enzyme of the following (a) or (b): (a) an enzyme comprising the amino acid sequence of SEQ ID NO:1 at least from position 1 to position 362, wherein the tyrosine at position 277 of SEQ ID NO:1 is substituted with alanine, tryptophan, isoleucine, or histidine, and having the ability to hydrolyze a substrate; or (b) an enzyme comprising the amino acid sequence of SEQ ID NO:1 at least from position 1 to position 362, wherein the tyrosine at position 277 of SEQ ID NO:1 is substituted with an amino acid other than tyrosine, and having the ability to hydrolyze a substrate.
    Type: Grant
    Filed: December 18, 2012
    Date of Patent: April 8, 2014
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Toshihiko Akiyama, Norihiko Hirata, Shinji Hourai
  • Thermostable esterase and its gene
    Patent number: 6518053
    Abstract: The present invention relates to an isolated or modified esterase having the excellent thermostable property which can be utilized for ester hydrolysis reaction, ester synthesis reaction, ester interchange reaction and its gene. The esterase is characterized in that it has at least a partial amino acid sequence necessary for expressing the thermostable esterase activity among the amino acid sequence shown by SEQ ID NO: 2 and further has an amino acid substitution described herein.
    Type: Grant
    Filed: August 9, 2001
    Date of Patent: February 11, 2003
    Assignee: Sumitomo Chemical Co., Ltd.
    Inventors: Shinji Hourai, Yasushi Matsuki
  • Thermostable esterase and its gene
    Publication number: 20020127686
    Abstract: The present invention relates to an esterase having the excellent thermostable property which can be utilized for ester hydrolysis reaction, ester synthesis reaction, ester interchange reaction and the like and its gene.
    Type: Application
    Filed: August 9, 2001
    Publication date: September 12, 2002
    Applicant: Sumitomo Chemical Co., Ltd.
    Inventors: Shinji Hourai, Yasushi Matsuki
  • Thermostable esterase and its gene
    Patent number: 6372470
    Abstract: The present invention relates to an isolated or modified esterase having the excellent thermostable property which can be utilized for ester hydrolysis reaction, ester synthesis reaction, ester interchange reaction and its gene. The esterase is characterized in that it has at least a partial amino acid sequence necessary for expressing the thermostable esterase activity among the amino acid sequence shown by SEQ ID NO: 2 and further has an amino acid substitution described herein.
    Type: Grant
    Filed: June 29, 1999
    Date of Patent: April 16, 2002
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Shinji Hourai, Yasushi Matsuki