Patents by Inventor Shinji Okabe
Shinji Okabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12089463Abstract: A display device according to an aspect of the disclosure includes a first metal protrusion being in contact with a first power-source trunk wire, and a second metal protrusion being in contact with a second power-source trunk wire. A first bank defining the end of an organic sealing film includes the first metal protrusion, the second metal protrusion, and a first resin protrusion. The first resin protrusion overlaps the first and second metal protrusions. The first resin protrusion has a frame shape.Type: GrantFiled: September 19, 2019Date of Patent: September 10, 2024Assignee: SHARP KABUSHIKI KAISHAInventors: Tohru Okabe, Shinsuke Saida, Shinji Ichikawa, Ryosuke Gunji, Akira Inoue, Yoshihiro Nakada, Hiroharu Jinmura
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Patent number: 12082449Abstract: A separation wall is provided in a frame shape along a circumferential edge of a through-hole in a non-display region, in which the through-hole is formed, defined in an island shape inside a display region. The separation wall includes a wall base portion provided in a frame shape by a part of a second interlayer insulating film and a resin layer provided in an eave shape on the wall base portion to extend to a through-hole side and a display region side. Opening portions opening upward are provided on peripheries of the wall base portion on the through-hole side and the display region side in the second interlayer insulating film.Type: GrantFiled: March 29, 2019Date of Patent: September 3, 2024Assignee: SHARP KABUSHIKI KAISHAInventors: Shinsuke Saida, Shinji Ichikawa, Ryosuke Gunji, Tohru Okabe, Akira Inoue, Yoshihiro Nakada, Hiroharu Jinmura
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Publication number: 20240165258Abstract: Disclosed is a stable aqueous pharmaceutical composition or lyophilized pharmaceutical composition comprising a protein as the active ingredient. The pharmaceutical composition comprises a protein having physiological activity and two different nonionic surfactants, including polysorbate 80 and polyoxyethylene(160) polyoxypropylene(30) glycol as the nonionic surfactants, for example, and as optional components, sodium chloride as a neutral salt, sucrose as a disaccharide and citrate buffer as a buffering agent.Type: ApplicationFiled: March 23, 2022Publication date: May 23, 2024Applicant: JCR PHARMACEUTICALS CO., LTD.Inventors: Hidehito Yasukawa, Hiroaki Murase, Yuka Yamaguchi, Shinji Okabe
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Patent number: 11932699Abstract: Aqueous pharmaceutical compositions containing a fusion protein of an antibody and a lysosomal enzyme as an active ingredient, which are stable enough to be marketed, are disclosed. The aqueous pharmaceutical composition, for example, comprises the fusion protein of the antibody and the lysosomal enzyme at a concentration of 0.5 to 20 mg/mL, sodium chloride at a concentration of 0.3 to 1.2 mg/mL, sucrose at a concentration of 50 to 100 mg/mL, a nonionic surfactant at a concentration of 0.15 to 3 mg/mL, a buffer at a concentration of 3 to 30 mM, and is adjusted to pH 5.0 to 7.5.Type: GrantFiled: September 7, 2018Date of Patent: March 19, 2024Assignee: JCR Pharmaceuticals Co., Ltd.Inventors: Hidehito Yasukawa, Yuka Yamaguchi, Shinji Okabe
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Patent number: 11738068Abstract: An aqueous preparation containing a protein as an active ingredient which is stable in storage in solution and makes an injection pain reduced is provided. More specifically an aqueous preparation containing a phosphate buffer at a concentration of 1 to 20 mM and a protein as an active ingredient is provided. Further more specifically provided is an aqueous preparation containing a phosphate buffer at a concentration of 1 to 20 mM, human growth hormone as an active ingredient, a poloxamer as a non-ionic surfactant; and phenol as a isotonic agent.Type: GrantFiled: June 25, 2019Date of Patent: August 29, 2023Assignee: JCR Pharmaceuticals Co., Ltd.Inventors: Hidehito Yasukawa, Takashi Hanada, Junya Tani, Shinji Okabe, Yuuka Asano
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Patent number: 11696940Abstract: An aqueous preparation containing a protein as an active ingredient which is stable in storage in solution and makes an injection pain reduced is provided. More specifically an aqueous preparation containing a phosphate buffer at a concentration of 1 to 20 mM and a protein as an active ingredient is provided. Further more specifically provided is an aqueous preparation containing a phosphate buffer at a concentration of 1 to 20 mM, human growth hormone as an active ingredient, a poloxamer as a non-ionic surfactant; and phenol as a isotonic agent.Type: GrantFiled: June 25, 2019Date of Patent: July 11, 2023Assignee: JCR Pharmaceuticals Co., Ltd.Inventors: Hidehito Yasukawa, Takashi Hanada, Junya Tani, Shinji Okabe, Yuuka Asano
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Publication number: 20220378882Abstract: The present invention discloses an aqueous pharmaceutical composition containing a protein in which serum albumin and growth hormone are linked. The aqueous pharmaceutical composition contains, as an active ingredient, a fusion protein of human serum albumin and human growth hormone; the concentration of the fusion protein is 10-100 mg/mL; the concentration of sucrose is 10-150 mg/mL; the concentration of a nonionic surfactant is 0.15-10 mg/mL; the concentration of a preservative is 0.5-12 mg/mL; the concentration of a buffer is 1-30 mM; and the pH is 5.0-8.0.Type: ApplicationFiled: October 29, 2020Publication date: December 1, 2022Applicant: JCR Pharmaceuticals Co., Ltd.Inventors: Shinji OKABE, Yuka YAMAGUCHI, Hidehito YASUKAWA
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Publication number: 20210252112Abstract: An aqueous preparation containing a protein as an active ingredient which is stable in storage in solution and makes an injection pain reduced is provided. More specifically an aqueous preparation containing a phosphate buffer at a concentration of 1 to 20 mM and a protein as an active ingredient is provided. Further more specifically provided is an aqueous preparation containing a phosphate buffer at a concentration of 1 to 20 mM, human growth hormone as an active ingredient, a poloxamer as a non-ionic surfactant; and phenol as a isotonic agent.Type: ApplicationFiled: June 25, 2019Publication date: August 19, 2021Applicant: JCR Pharmaceuticals Co., Ltd.Inventors: Hidehito YASUKAWA, Takashi HANADA, Junya TANI, Shinji OKABE, Yuuka ASANO
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Publication number: 20210187082Abstract: [Problem] To provide a pharmaceutical composition containing a fusion protein comprising an antibody and a lysosomal enzyme as an active ingredient, which is stable enough to permit its distribution to the market. [Solution] A lyophilized formulation containing; a fusion protein comprising an antibody and a lysosomal enzyme as an active ingredient, and further containing a neutral salt, a disaccharide, a nonionic surfactant, and a buffer. Such a lyophilized formulation includes, for example, as an active ingredient, a fusion protein comprising an anti-transferrin receptor antibody and human iduronate-2-sulfatase, and further containing sodium chloride as the neutral salt, sucrose as the disaccharide, poloxamer as the nonionic surfactant, and phosphate buffer as the buffer.Type: ApplicationFiled: February 22, 2021Publication date: June 24, 2021Applicant: JCR Pharmaceuticals Co., Ltd.Inventors: Hidehito Yasukawa, Yuka Yamaguchi, Shinji Okabe
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Patent number: 10940185Abstract: [Problem] To provide a pharmaceutical composition containing a fusion protein comprising an antibody and a lysosomal enzyme as an active ingredient, which is stable enough to permit its distribution to the market. [Solution] A lyophilized formulation containing; a fusion protein comprising an antibody and a lysosomal enzyme as an active ingredient, and further containing a neutral salt, a disaccharide, a nonionic surfactant, and a buffer. Such a lyophilized formulation includes, for example, as an active ingredient, a fusion protein comprising an anti-transferrin receptor antibody and human iduronate-2-sulfatase, and further containing sodium chloride as the neutral salt, sucrose as the disaccharide, poloxamer as the nonionic surfactant, and phosphate buffer as the buffer.Type: GrantFiled: December 28, 2017Date of Patent: March 9, 2021Assignee: JCR Pharmaceuticals Co., Ltd.Inventors: Hidehito Yasukawa, Yuka Yamaguchi, Shinji Okabe
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Publication number: 20210061918Abstract: Aqueous pharmaceutical compositions containing a fusion protein of an antibody and a lysosomal enzyme as an active ingredient, which are stable enough to be marketed, are disclosed. The aqueous pharmaceutical composition, for example, comprises the fusion protein of the antibody and the lysosomal enzyme at a concentration of 0.5 to 20 mg/mL, sodium chloride at a concentration of 0.3 to 1.2 mg/mL, sucrose at a concentration of 50 to 100 mg/mL, a nonionic surfactant at a concentration of 0.15 to 3 mg/mL, a buffer at a concentration of 3 to 30 mM, and is adjusted to pH 5.0 to 7.5.Type: ApplicationFiled: September 7, 2018Publication date: March 4, 2021Applicant: JCR Pharmaceuticals Co., Ltd.Inventors: Hidehito YASUKAWA, Yuka YAMAGUCHI, Shinji OKABE
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Publication number: 20190336586Abstract: [Problem] To provide a pharmaceutical composition containing a fusion protein comprising an antibody and a lysosomal enzyme as an active ingredient, which is stable enough to permit its distribution to the market. [Solution] A lyophilized formulation containing; a fusion protein comprising an antibody and a lysosomal enzyme as an active ingredient, and further containing a neutral salt, a disaccharide, a nonionic surfactant, and a buffer. Such a lyophilized formulation includes, for example, as an active ingredient, a fusion protein comprising an anti-transferrin receptor antibody and human iduronate-2-sulfatase, and further containing sodium chloride as the neutral salt, sucrose as the disaccharide, poloxamer as the nonionic surfactant, and phosphate buffer as the buffer.Type: ApplicationFiled: December 28, 2017Publication date: November 7, 2019Applicant: JCR Pharmaceuticals Co., Ltd.Inventors: Hidehito Yasukawa, Yuka Yamaguchi, Shinji Okabe
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Publication number: 20020002515Abstract: A reception server receives a formation request for forming an image from a user terminal through a network. A seller forms a digital image based on digital data of an original image, and registers the formed digital image in an art database. The seller informs a requester of the formation request about completion of forming the digital image. The reception server reads out a corresponding digital image from the art database, and displays the read digital image on the user terminal, in response to a request from the user terminal. If a button “OK” is clicked on the user terminal, the reception server executes a predetermined payment process. After it is confirmed that the requester has paid for the requested image, the reception server permits the user terminal to download the digital image. The requester then outputs the digital image, downloaded using the user terminal, using a printer.Type: ApplicationFiled: May 22, 2001Publication date: January 3, 2002Inventors: Hiromichi Okazaki, Kiyomi Ikeda, Shinji Okabe, Naoko Shijo
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Patent number: 6037559Abstract: A circular blank made of a steel plate is lapped onto an Al-based plate in lapped areas of the Al alloy plate and another steel plate. Then, the three members are pressed by a pair of electrodes, and a welding current is allowed to flow between both the electrodes, thereby sequentially performing the melting of a current-supplied portion of the Al alloy plate and a portion near the current-supplied portion, the elimination of a molten portion by a partial bulgy deformation of the blank toward the Al alloy plate, the abutment of the bulgy deformed portion against the steel plate, and the resistance-welding between the bulgy deformed portion and the steel plate.Type: GrantFiled: March 17, 1998Date of Patent: March 14, 2000Assignee: Honda Giken Kogyo Kabushiki KaishaInventors: Shinji Okabe, Takanori Yahaba
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Patent number: 5753885Abstract: A powder material for use in resistance welding articles of aluminum comprises a mixture of 10-50% by weight of a liquid resin and the remaining proportion of a magnesium powder or a blend of magnesium and aluminum powders. Also a method of resistance welding articles of aluminum comprises the steps of preparing a pasty mixture by mixing in a predetermined amount of a liquid resin having a predetermined initial viscosity, a predetermined amount of a metal powder or a blend of metal and metal oxide powders, and inserting the pasty mixture between the mating weld surfaces of the aluminum articles. Only a small welding force and a low current will be required in producing a resistance weld connection between the aluminum articles with desired strength.Type: GrantFiled: June 23, 1995Date of Patent: May 19, 1998Assignee: Honda Giken Kogyo Kabushiki KaishaInventors: Takashi Iwasa, Shinji Okabe, Mitsuru Noguchi, Takanori Yahaba
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Patent number: 5599467Abstract: An aluminum weldment is produced by resistance-welding aluminum workpieces, and has a nugget formed between the aluminum workpieces which contains more magnesium than the base material of the aluminum workpieces. The nugget contains 5.about.17 wt % of magnesium which forms a solid solution with aluminum.Type: GrantFiled: November 16, 1994Date of Patent: February 4, 1997Assignees: Honda Giken Kogyo Kabushiki Kaisha, Showa Aluminum CorporationInventors: Shinji Okabe, Takashi Iwasa, Takushi Irie, Yuichi Furukawa, Ichiro Iwai
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Patent number: 5565117Abstract: Workpieces of aluminum alloy are resistance-welded while a powdery mixture of magnesium and a metal oxide is being interposed between regions of workpieces of aluminum alloy which are to be joined to each other. The metal oxide may comprise at least one material selected from the group consisting of TiO.sub.2, SiO.sub.2, Cr.sub.2 O.sub.3, MnO.sub.2, Fe.sub.2 O.sub.3, CuO, and Ti.sub.2 O.sub.3 and the powdery mixture may include aluminum powder. The workpieces may be made of aluminum, stainless steel, or the like rather than aluminum alloy.Type: GrantFiled: December 27, 1994Date of Patent: October 15, 1996Assignees: Honda Giken Kogyo Kabushiki Kaisha, Showa Aluminum CorporationInventors: Takashi Iwasa, Shinji Okabe, Takushi Irie, Yuichi Furukawa, Ichiro Iwai