Abstract: To provide a marker for determining sensitivity of a patient to an anti-cancer agent, and novel cancer therapeutic means employing the marker. The marker for determining sensitivity to an anti-cancer agent is formed of a protein selected from the group consisting of a protein or a fragment thereof which is detected as a peak at m/z of 16,450 to 16,620, a protein or a fragment thereof which is detected as a peak at m/z of 22,080 to 22,310, and a protein or a fragment thereof which is detected as a peak at m/z of 17,100 to 17,270, the peaks being determined by means of a mass spectrometer.

Abstract: To provide a marker for determining sensitivity of a patient to an anti-cancer agent, and novel cancer therapeutic means employing the marker.

Abstract: A rotary electric machine includes a stator having stator windings; and a rotor rotatably disposed in the stator, said rotor having a rotor core provided with a plurality of magnets and a plurality of magnetic auxiliary salient poles formed between poles of the magnets. In this rotary electric machine: a magnetic air gap is provided in an axial direction of the rotor in a position shifted in a circumferential direction from a q axis passing through a center of the magnetic auxiliary salient pole within the magnetic auxiliary salient pole; and an amount of shifting the magnetic air gap from the q axis in the circumferential direction differs according to a position of the magnetic air gap in the axial direction so as to cancel torque pulsation in energization caused due to the magnetic air gap.

Abstract: A rotating electric machine for vehicular use includes: a stator that includes a stator core and a stator winding wound at the stator core; and a rotor that is rotatably disposed relative to the stator and includes a rotor core formed by laminating a plurality of electromagnetic steel sheets with a plurality of magnet insertion holes formed therein and includes a plurality of permanent magnets each held in each of the plurality of magnet insertion holes to form a magnetic pole. Each of the plurality of permanent magnets extends along a rotor axis and is formed in a shape assuming at least two different lengths along a circumference of the rotor.

Abstract: A culture apparatus includes a culture chamber in which culture is cultured, a shelf plate included in the culture chamber, on which the culture is placed, and shelf rests in a left-and-right pair configured to support the shelf plate and a plurality of shelf supports configured to support the shelf rests. The shelf rests each include one piece supporting the shelf plate and the other piece supported by the shelf supports. The shelf rests are in an L-shape in a cross-sectional manner whose angle between the one piece and the other piece is an acute angle. The one piece is in line contact with a lower face of the shelf plate at an end of the one piece extending obliquely upward from a side face of the culture chamber toward the inside of the culture chamber. The culture chamber is supplied with sterilizing gas to be sterilized.

Abstract: A method for analyzing an operating point of a permanent magnet performs electromagnetic field analysis based on a B-H curve of the permanent magnet and element data concerning a finite number of elements into which the permanent magnet is divided to obtain the operating point of the permanent magnet. The method includes the steps of storing data of inputted B-H curve; obtaining magnetic flux densities and magnetic fields in plural regions of the permanent magnet by performing the electromagnetic field analysis based on the data of the B-H curve; and obtaining the operating point of each of the elements based on the result of the electromagnetic field analysis by employing a variable, the variable continuously varying in a first quadrant, in a second quadrant, in a third quadrant, and over these quadrants of the B-H curve and linearly varying with respect to the magnetic flux density and magnetic field.

Abstract: A rotating electric machine includes a stator having a stator coil and a rotor provided rotatably around a specific rotation axis with respect to the stator. The rotor includes a plurality of magnets, a plurality of magnetically-assisted salient pole members provided between poles of any adjacent two magnets from among the plurality of magnets, and a magnetoresistance variation unit provided in the magnetically-assisted salient pole member along an axial direction of the rotation axis at a position offset in a circumferential direction of the rotation axis from a q-axis passing through a salient pole center of the magnetically-assisted salient pole member. The amount of offset of the magnetoresistance variation unit from the q-axis varies depending on positions of the magnetically-assisted salient pole members so that torque fluctuations cancel each other when power is applied.

Abstract: This rotating electrical machine includes a stator, a rotor having a plurality of convex portions on its surface that opposes the stator and extending along its direction of rotation, a magnet, and a frame made from magnetic material. The number of poles of the stator is the same as the number of magnetic convex poles of the rotor. The rotor is made from a plurality of plates of magnetic material, superimposed and skewed along the axial direction. A magnetic circuit is set up in the frame so that the magnetic flux of the magnet flows therein from the central portion of the rotor. And the magnet is a permanent magnet shaped as a cylinder, is single-pole magnetized along the radial direction, and is provided between the outer circumferential surface of the stator in the circumferential direction and the inner circumferential surface of the frame in the circumferential direction.

Abstract: A rotating electrical machine includes: a stator that includes a cylindrical stator core and a stator winding wire wound around the stator core; and a rotor disposed facing the stator via a gap; wherein at least one cooling medium path extending in a direction of a central axis of the stator core is provided in the stator; and the cooling medium path is inclined relative to the central axis of the stator core.

Abstract: Provided are a marker for determining sensitivity to an anticancer agent capable of distinguishing a therapeutic response of an individual patient and a novel means for a cancer therapy using the marker. The marker for determining sensitivity to an anticancer agent contains a substance in a metabolic pathway in which L-phenylalanine and/or N,N-dimethyl glycine are/is involved.

Abstract: Provided are an marker for determining sensitivity to an anticancer agent capable of distinguishing a therapeutic response of an individual patient and a novel means for a cancer therapy using the marker. The marker for determining sensitivity to an anticancer agent contains a calcium-binding protein S100A7, S100A8, or S100A10.

Abstract: A culture apparatus includes a culture chamber in which culture is cultured, a shelf plate included in the culture chamber, on which the culture is placed, and shelf rests in a left-and-right pair configured to support the shelf plate and a plurality of shelf supports configured to support the shelf rests. The shelf rests each include one piece supporting the shelf plate and the other piece supported by the shelf supports. The shelf rests are in an L-shape in a cross-sectional manner whose angle between the one piece and the other piece is an acute angle. The one piece is in line contact with a lower face of the shelf plate at an end of the one piece extending obliquely upward from a side face of the culture chamber toward the inside of the culture chamber. The culture chamber is supplied with sterilizing gas to be sterilized.

Abstract: A rotary electric machine includes a stator having stator windings; and a rotor rotatably disposed in the stator, said rotor having a rotor core provided with a plurality of magnets and a plurality of magnetic auxiliary salient poles formed between poles of the magnets. In this rotary electric machine: a magnetic air gap is provided in an axial direction of the rotor in a position shifted in a circumferential direction from a q axis passing through a center of the magnetic auxiliary salient pole within the magnetic auxiliary salient pole; and an amount of shifting the magnetic air gap from the q axis in the circumferential direction differs according to a position of the magnetic air gap in the axial direction so as to cancel torque pulsation in energization caused due to the magnetic air gap.

Abstract: The present invention relates to a cylindrical poly-V pulley made of metal sheet suitable for forcedly fitting a one-way clutch or a bearing. The present invention can easily provide thick ears for preventing a V-belt from disengaging, and ensure an enough length of an axial straight line of a bore of a peripheral wall. Ears (2, 2) for preventing the V-belt from disengaging, are protrusively shaped in an annular state on axially both ends on an outer surface of a cylindrical peripheral wall (1). The each ear (2) includes an inner ear portion (2a) outwardly protruded from the both ends of the peripheral wall (1) and an outer ear portion (2b) folded back from the protruded outer end of the inner ear portion (2a) to the outer surface of the inner ear portion (2a) so as to be closely overlapped with each other, and the inner end surface of the ear (2) is flush with the inner surface of the peripheral wall (1).

Abstract: The present invention relates to a cylindrical poly-V pulley made of metal sheet suitable for forcedly fitting a one-way clutch or a bearing. The present invention can easily provide thick ears for preventing a V-belt from disengaging, and ensure an enough length of an axial straight line of a bore of a peripheral wall. Ears (2, 2) for preventing the V-belt from disengaging, are protrusively shaped in an annular state on axially both ends on an outer surface of a cylindrical peripheral wall (1). The each ear (2) includes an inner ear portion (2a) outwardly protruded from the both ends of the peripheral wall (1) and an outer ear portion (2b) folded back from the protruded outer end of the inner ear portion (2a) to the outer surface of the inner ear portion (2a) so as to be closely overlapped with each other, and the inner end surface of the ear (2) is flush with the inner surface of the peripheral wall (1).

Abstract: The present invention relates to a cylindrical poly-V pulley made of metal sheet suitable for forcedly fitting a one-way clutch or a bearing. The present invention can easily provide thick ears for preventing a V-belt from disengaging, and ensure an enough length of an axial straight line of a bore of a peripheral wall. Ears for preventing the V-belt from disengaging, are protrusively shaped in an annular state on axially both ends on an outer surface of a cylindrical peripheral wall. Each ear includes an inner ear portion outwardly protruded from both ends of the peripheral wall and an outer ear portion folded back from the protruded outer end of the inner ear portion to the outer surface of the inner ear portion so as to be closely overlapped with each other, and the inner end surface of the ear is flush with the inner surface of the peripheral wall.

Abstract: The present invention relates a method of producing a sheet metal poly-V groove pulley in which a thickened annular peripheral wall of an outer peripheral side of a base plate is holding held and pressed so as to increase the axial length of the annular peripheral wall, thereby forming a drum wall and preliminary ears projected from the root portion of the drum wall, and thereafter a step of forming poly-V grooves and ears is performed so that poly-V grooves and ears which are obtained by further projecting the preliminary ears and have a single layer structure are formed on the drum wall. According to this method, the preliminary ears are previously formed and then further projected so as to form the ears. Even when a sheet metal member is thin, therefore, ears of a single-layer structure which has a sufficient projection degree can be obtained.