Patents by Inventor Shinkichi Honda
Shinkichi Honda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6800433Abstract: The present invention relates to a process for purifying dimeric to pentameric proanthocyanidin oligomers which comprises extracting the proanthocyanidin oligomers from raw materials containing the proanthocyanidin oligomers or crude purification products therefrom by solid-liquid extraction using methyl acetate as a liquid phase; a process for purifying dimeric to pentameric proanthocyanidin oligomers which comprises pretreating with an enzyme for hydrolysis raw materials containing the proanthocyanidin oligomers, crude purification products therefrom, or a solution containing one of these; and a process for purifying dimeric to pentameric proanthocyanidin oligomers with a uniform polymerization degree which comprises separating and purifying the proanthocyanidin oligomers by polymerization degree from raw materials containing the proanthocyanidin oligomers or crude purification products there from by normal phase silica gel liquid chromatography using as a mobile phase a single solvent or a mixed solvent ofType: GrantFiled: October 19, 2001Date of Patent: October 5, 2004Assignees: Kyowa Hakko Kogyo Co., Ltd., The Nikka Whisky Distilling Co., Ltd.Inventors: Shinkichi Honda, Tomoya Takahashi, Ayako Kamimura, Takako Matsuoka, Tomomasa Kanda, Akio Yanagida, Kazuo Hieda
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Publication number: 20040052803Abstract: Skin care products for alleviating problems caused by deterioration of skin immunity.Type: ApplicationFiled: June 26, 2003Publication date: March 18, 2004Inventors: Chihiro Kaise, Masako Kobayashi, Teruhisa Kaneko, Shinkichi Honda
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Patent number: 6562804Abstract: The present invention provides a hair-growing agent comprising, as an active ingredient, a phosphatidic acid represented by formula (I): (wherein R1 represents alkyl, alkenyl, alkanoyl or alkenoyl; and when R1 represents alkyl or alkenyl, R2 represents alkyl, alkenyl, alkanoyl or alkenoyl, and when R1 represents alkanoyl or alkenoyl, R2 represents alkyl or alkenyl).Type: GrantFiled: February 12, 2002Date of Patent: May 13, 2003Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Ayako Kamimura, Tomoya Takahashi, Takashi Mimura, Shinkichi Honda
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Patent number: 6562803Abstract: The present invention provides a hair-growing agent comprising, as an active ingredient, a phosphatidic acid represented by formula (I): (wherein R1 represents straight-chain alkyl having an odd number of carbon atoms, straight-chain alkenyl having an odd number of carbon atoms, or straight-chain alkynyl having an odd number of carbon atoms).Type: GrantFiled: February 12, 2002Date of Patent: May 13, 2003Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Ayako Kamimura, Tomoya Takahashi, Takashi Mimura, Shinkichi Honda
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Publication number: 20020172657Abstract: The present invention provides a hair-growing agent comprising, as an active ingredient, a phosphatidic acid represented by formula (I): 1Type: ApplicationFiled: February 12, 2002Publication date: November 21, 2002Applicant: Kyowa Hakko Kogyo Co., Ltd.Inventors: Ayako Kamimura, Tomoya Takahashi, Takashi Mimura, Shinkichi Honda
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Publication number: 20020155085Abstract: The present invention provides a hair-growing agent comprising, as an active ingredient, a phosphatidic acid represented by formula (I): 1Type: ApplicationFiled: February 12, 2002Publication date: October 24, 2002Applicant: Kyowa Hakko Kogyo Co., Ltd.Inventors: Ayako Kamimura, Tomoya Takahashi, Takashi Mimura, Shinkichi Honda
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Patent number: 6350783Abstract: The present invention relates to a cleansing composition comprising at least one compound selected from N-long chain acylamino acids represented by formula (I): (wherein n represents 1 or 2; and R represents a saturated or unsaturated hydrocarbon group having 5 to 23 carbon atoms), and salts thereof.Type: GrantFiled: November 4, 1998Date of Patent: February 26, 2002Assignee: Kyowa Hakko KogyoInventors: Shinkichi Honda, Mikio Tsuboi
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Publication number: 20010055576Abstract: The present invention relates to a cleansing composition comprising at least one compound selected from N-long chain acylamino acids represented by formula (I): 1Type: ApplicationFiled: November 4, 1998Publication date: December 27, 2001Inventors: SHINKICHI HONDA, MIKIO TSUBOI
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Patent number: 6288023Abstract: The present invention relates to a cleansing composition comprising at least one compound selected from N-long chain acylamino acids represented by formula (I): (wherein n represents 1 or 2; and R represents a saturated or unsaturated hydrocarbon group having 5 to 23 carbon atoms), and salts thereof.Type: GrantFiled: March 16, 2000Date of Patent: September 11, 2001Assignee: Kyowa Hakko Kogyo, Co., Ltd.Inventors: Shinkichi Honda, Mikio Tsuboi
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Patent number: 6018037Abstract: A novel motilin analog peptide containing leucine instead of the usual 13th amino acid methionine, as in the naturally occurring motilin, is produced by gene recombination techniques in which several or identical genes, each coding for the novel peptide, are joined in series into a vector. The resultant recombinant DNA is introduced into Escherichia coli and the resultant transformant is cultivated. The resulting polymeric peptide can be cleaved to give the desired peptide.Type: GrantFiled: November 20, 1997Date of Patent: January 25, 2000Assignee: Kyowa Hakko Kogyo Co., LtdInventors: Shinkichi Honda, Tatsunari Nishi, Seiga Itoh, Moriyuki Sato
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Patent number: 5721353Abstract: A novel motilin analog peptide containing leucine instead of the usual 13th amino acid methionine, as in the naturally occurring motilin, is produced by gene recombination techniques in which several or identical genes, each coding for the novel peptide, are joined in series into a vector. The resultant recombinant DNA is introduced into Escherichia coli and the resultant transformant is cultivated. The resulting polymeric peptide can be cleaved to give the desired peptide.Type: GrantFiled: February 13, 1995Date of Patent: February 24, 1998Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Shinkichi Honda, Tatsunari Nishi, Seiga Itoh, Moriyuki Sato
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Patent number: 5695952Abstract: A novel motilin analog peptide containing leucine instead of the usual 13th amino acid methionine, as in the naturally occurring motilin, is produced by gene recombination techniques in which several or identical genes, each coding for the novel peptide, are joined in series into a vector. The resultant recombinant DNA is introduced into Escherichia coli and the resultant transformant is cultivated. The resulting polymeric peptide can be cleaved to give the desired peptide.Type: GrantFiled: May 25, 1995Date of Patent: December 9, 1997Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Shinkichi Honda, Tatsunari Nishi, Seiga Itoh, Moriyuki Sato
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Patent number: 5468474Abstract: The present invention relates to N-acylglutamine derivatives of formula (I): ##STR1## The N-acylglutamine derivatives are well compatible with oily bases and have good skin-moisturizing activity and hair growth-stimulative effect. These are useful as cosmetics and hair growth stimulants.Type: GrantFiled: July 27, 1994Date of Patent: November 21, 1995Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Shinkichi Honda, Kenji Torii, Yoichiro Arai, Masaji Kasai, Hiromasa Kato, Takao Iida, Tomoya Takahashi, Yoshiharu Yokoo, Toshikazu Kamiya, Tatsuya Tamaoki
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Patent number: 5420113Abstract: A novel motilin analog peptide containing leucine instead of the usual 13th amino acid methionine, as in the naturally occurring motilin, is produced by gene recombination techniques in which several or identical genes, each coding for the novel peptide, are joined in series into a vector. The resultant recombinant DNA is introduced into Escherichia coli and the resultant transformant is cultivated. The resulting polymeric peptide can be cleaved to give the desired peptide.Type: GrantFiled: July 22, 1993Date of Patent: May 30, 1995Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Shinkichi Honda, Tatsunari Nishi, Seiga Itoh, Moriyuki Sato
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Patent number: 5380359Abstract: A melanin-coated pigment obtained by coating a carrier with a readily alkali-soluble natural melanin, and a cosmetic containing the pigment are provided. The melanin-coated pigment is highly safe and has high coloring and high saturation tone, and a cosmetic which contains it is also expected to have ultraviolet-ray-absorbing and anti-oxidizing effects.Type: GrantFiled: November 24, 1993Date of Patent: January 10, 1995Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Shinkichi Honda, Yoichiro Takekoshi, Yoichiro Arai
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Patent number: 5112613Abstract: Disclosed is a cosmetic composition comprising N-acetylglutamine or a salt thereof.The cosmetic composition of the present invention which is excellent in feel and stability is effective in retaining moisture in the stratum corneum.Type: GrantFiled: January 23, 1991Date of Patent: May 12, 1992Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Shinkichi Honda, Yoichiro Arai, Hiroshi Toida