Abstract: A microscope system comprises a microscope body, an image sensor mounted on the microscope body, and a stage that moves in an X-axis direction and a Y-axis direction, and places a slide as an observation object. The stage includes a mark used to indicate a stage reference position. The microscope system obtains positions of the stage in the X-axis direction and the Y-axis direction, and detects the stage reference position indicated by a mark provided on the stage and a slide reference position indicated by a mark provided on a slide placed on the stage. The microscope system manages the position of the stage by coordinates based on the slide reference position if the slide reference position is detected, and manages the position of the stage by coordinates based on the stage reference position if the slide reference position is not detected.

Abstract: The present disclosure has an object of providing a tactile sensor having a simple structure and capable of detecting a shear force, and a tactile sensor unit constituting the tactile sensor. The present disclosure relates to a tactile sensor unit including: a plurality of pressure-sensitive elements each including a first substrate including a first electrode, a second electrode disposed facing the first electrode, and a dielectric disposed between the first electrode and the second electrode; and an external force acting portion disposed on and across the plurality of pressure-sensitive elements, wherein, when a shear force is applied to the external force acting portion, at least a part of the pressure-sensitive elements change in inter-electrode electrostatic capacitance.

Abstract: A microscope system comprises a microscope body, a stage configured to place a slide as an observation target and move in an X direction and a Y direction. The microscope system changes an arrangement of the placed slide with respect to the stage so as to cause a direction indicated by a mark provided on the slide placed on the stage to align with one of the X direction and the Y direction of the stage.

Abstract: The present disclosure provides a pressure-sensitive element having a relatively wide pressing force measurement range and a relatively simple structure. Pressure-sensitive element is provided with pressure-sensitive part that receives pressing force and detector that detects the pressing force, and has a structure described below. That is, pressure-sensitive part has first conductive member that has elasticity, second conductive member, and dielectric body. Dielectric body is disposed between first conductive member and second conductive member, and at least partially covers the surface of first conductive member or second conductive member. Detector detects pressing force based on a variation in electrostatic capacitance between first conductive member and second conductive member.

Abstract: A slide used for observation by a microscope includes a label area configured to arrange a label, a cover glass area configured to arrange an observation object and a cover glass, a position reference mark arranged in a vacant area between the label area and the cover glass area and configured to specify a reference position of the slide and an X-axis direction and a Y-axis direction that are orthogonal to each other, and focus reference marks in which a predetermined pattern is repetitively arranged along two opposing sides of four sides of a periphery of the cover glass area, the focus reference marks being configured to specify a Z-axis direction orthogonal to the X-axis direction and the Y-axis direction.

Abstract: A microscope system includes an observation optical system including an objective lens, an imaging unit configured to capture an image of an observation object obtained by the observation optical system, and a stage movable in an X-axis direction, a Y-axis direction, and a Z-axis direction, on which a slide of the observation object is placed. The microscope system obtains position information defined by the X-axis direction, the Y-axis direction, and the Z-axis direction, and stores the obtained position information and the image of the observation object obtained by capturing the observation object by the imaging unit in a storage in association with each other.

Abstract: A microscope system includes an observation optical system including an objective lens, an XY stage capable of moving an XY plane in an X-axis direction and an Y-axis direction, a first change unit configured to change a slant of the XY plane with respect to an optical axis direction of the objective lens, and a second change unit configured to change a slant of a slide placed on the XY stage with respect to the XY plane. Changing the slant of the XY plane by the first change unit is performed based on a first mark arranged on the XY plane at a position observable by the observation optical system. Changing the slant of the slide with respect to the XY plane by the second change unit is performed based on a second mark arranged on the slide.

Abstract: A microscope system includes a microscope body, a camera connected to an observation optical system of the microscope body, and an XY stage on which a slide of an observation object is placed and which is configured to move in an X-axis direction and a Y-axis direction that are orthogonal to each other. The XY stage includes an XY two-dimensional scale plate. The XY two-dimensional scale plate includes a first mark configured to provide X-axis direction axis information and Y-axis direction axis information of the stage, and a second mark which is provided within an observable region of the camera on the same plane as the first mark and which is available for recognizing a position of an XY plane of the first mark in a Z-axis direction at each of a plurality of points by focus detection of the camera.

Abstract: A microscope system comprises a microscope body, an image sensor mounted on the microscope body via mounting means and configured to capture an observation image under a microscope, and a stage that moves in an X-axis direction and a Y-axis direction, which are orthogonal to each other, and places a slide as an observation object and includes a mark used to indicate a stage reference position. The microscope system obtains positions of the stage in the X-axis direction and the Y-axis direction, and detects, from an image captured by the image sensor, the stage reference position indicated by a mark provided on the stage and a slide reference position indicated by a mark provided on a slide placed on the stage. The microscope system manages the position of the stage by coordinates based on the slide reference position if the slide reference position is detected, and manages the position of the stage by coordinates based on the stage reference position if the slide reference position is not detected.

Abstract: A pressure sensing element according to one aspect of the present disclosure includes a first electrode including at least one protrusion, a second electrode facing the at least one protrusion, and a dielectric disposed between the first electrode and the second electrode. The dielectric includes a first dielectric and a second dielectric. The first dielectric is disposed between a top of the at least one protrusion and the second electrode, and is in contact with each of the top of the at least one protrusion and the second electrode. The second dielectric is disposed between a first portion of the first electrode and the first dielectric. The first portion does not include the at least one protrusion. The at least one protrusion has a higher elastic modulus than the first dielectric.

Abstract: A pressure sensor according to an aspect of the present disclosure includes: a first pressure sensitive element including a first conductive layer including first projections having conductivity, first wiring layers, and a first dielectric layer provided between the first projections and the first wiring layers; and a second pressure sensitive element including a second conductive layer including second projections having conductivity, second wiring layers, and a second dielectric layer provided between the second projections and the second wiring layers. The first pressure sensitive element and the second pressure sensitive element are stacked on each other.

Abstract: A microscope system comprises a microscope body, a stage configured to place a slide as an observation target and move in an X direction and a Y direction. The microscope system changes an arrangement of the placed slide with respect to the stage so as to cause a direction indicated by a mark provided on the slide placed on the stage to align with one of the X direction and the Y direction of the stage.

Abstract: A microscope system comprises a microscope body, an imaging unit connected to the microscope body and including an image sensor for capturing a microscopic image, and an XY stage configured to place a slide and move in an X direction and a Y direction. The microscope system changes an arrangement of the image sensor with respect to the microscope body so as to cause a direction defined by a pixel arrangement of the image sensor to align with one of the X direction and the Y direction of the XY stage.

Abstract: A microscope system includes a microscope body, an XY stage mounted on the microscope body and including a stage configured to place a slide as an observation target and move in an X-axis direction and a Y-axis direction perpendicular to each other, and an XY two-dimensional scale plate fixed to the stage. The XY two-dimensional scale plate is provided with a first mark that provides axis information in the X-axis direction throughout a movable range of the stage in the Y-axis direction and a second mark that provides axis information in the Y-axis direction throughout a movable range of the stage in the X-axis direction, which are used to recognize X- and Y-coordinates of the stage.

Abstract: A slide on which an observation object by a microscope is placed, is provided. A first mark indicating a reference line along a first direction and a second mark indicating a specific position on an extension of the reference line along the first direction are separately arranged in a vacant area between a label area used to arrange a label and a cover glass area used to arrange the observation object and a cover glass. A position reference is provided by the specific position on the extension of the reference line along the first direction.

Abstract: A pressure sensing element of an aspect of the present disclosure includes a first electrode including at least one protrusion having elasticity; a second electrode facing the at least one protrusion; and a dielectric disposed between the first electrode and the second electrode and including a first dielectric and a second dielectric. The first dielectric is disposed between a top of the at least one protrusion and the second electrode, and is in contact with each of the top of the at least one protrusion and the second electrode. The second dielectric is disposed between a first portion of the first electrode, the first portion not including the at least one protrusion, and the first dielectric.

Abstract: Disclosed herein are methods for detecting the presence and/or amount of HER2 protein, HER2 nucleic acid (for example, HER2 genomic DNA), ER protein, and Chromosome 17 centromere DNA in a single sample. Samples stained for HER2 protein, HER2 DNA, ER protein, and Chromosome 17 DNA allow for the identification of various types of cancer cells, for example HER2 protein positive/ER protein positive/HER2 gene positive cells, HER2 protein positive/ER protein negative/HER2 gene positive cells, HER2 protein negative/ER protein positive/HER2 gene positive cells, and HER2 protein negative/ER protein negative/HER2 gene positive cells.

Abstract: A pressure sensor according to an aspect of the present disclosure includes: a first pressure sensitive element including a first conductive layer including first projections having conductivity, first wiring layers, and a first dielectric layer provided between the first projections and the first wiring layers; and a second pressure sensitive element including a second conductive layer including second projections having conductivity, second wiring layers, and a second dielectric layer provided between the second projections and the second wiring layers. The first pressure sensitive element and the second pressure sensitive element are stacked on each other.

Abstract: A pressure sensor according to one aspect of the present disclosure includes a first dielectric layer that has elasticity and has a first surface and a second surface which is on an opposite side from the first surface, a first conductor layer that is arranged on at least a region of the first surface, a second conductor layer that is arranged on the second surface, and a first time-domain reflectometer that is connected with the first conductor layer and the second conductor layer, and the region of the first surface is opposed to the second conductor layer.

Abstract: A pressure sensing element according to one aspect of the present disclosure includes a first electrode including at least one protrusion, a second electrode facing the at least one protrusion, and a dielectric disposed between the first electrode and the second electrode. The dielectric includes a first dielectric and a second dielectric. The first dielectric is disposed between a top of the at least one protrusion and the second electrode, and is in contact with each of the top of the at least one protrusion and the second electrode. The second dielectric is disposed between a first portion of the first electrode and the first dielectric. The first portion does not include the at least one protrusion. The at least one protrusion has a higher elastic modulus than the first dielectric.