Abstract: A method for manufacturing a photochromic lens includes: a step of injecting a polymerizable composition through an injection part in an injection molding apparatus and filling a gap with the polymerizable composition through a space; a step of heating the filled polymerizable composition to be polymerized and cured and forming a photochromic layer on a resin substrate; and a step of taking out a resulting laminate composed of the resin substrate and the photochromic layer, in which the polymerizable composition includes an isocyanate compound, a thiol compound, a polyol compound, and a photochromic compound.

Abstract: A polymerizable composition for an optical material of the present invention includes (A) a compound of which pKa value is 1 to 9, (B) a di- or higher functional iso(thio)cyanate compound, and (C) a di- or higher functional active hydrogen compound.

Abstract: Sortilin is a sorting receptor that directs target proteins to the secretary or endocytic compartments of cells that is found in both extracellular vesicles and cells. Provided herein are methods and compositions for decreasing or inhibiting trafficking of sortilin to an extracellular vesicle, for example by inhibiting the formation of intermolecular sortilin dimers.

Abstract: A polymerizable composition for an optical material containing two or more different monomers for an optical material, and a polymerization catalyst, in which at least one of the two or more different monomers for an optical material is an isocyanate compound containing an aromatic ring, a content of the polymerization catalyst with respect to a total of 100 parts by mass of the two or more different monomers for an optical material is from 0.010 parts by mass to 0.50 parts by mass, and the viscosity measured by a B-type viscometer at 25° C. and 60 rpm is from 10 mPa·s to 1,000 mPa·s.

Abstract: The present invention addresses the problem of providing a material as a scaffold used to prevent poor skin grafting when there is a defect in the perichondrium or periosteum or a defect in subcutaneous tissue. As a solution, there is provided a dry amniotic membrane manufactured according to a specific drying process. In more detail, a raw amniotic membrane placed in a processing tank (10) is continuously heated by a far-infrared heater (14) provided inside the processing tank (10), while performing a decompression operation where the interior of the processing tank (10) is placed in a decompressed state and irradiation of the raw amniotic membrane with microwaves from a microwave generating device (30) provided inside the processing tank (10) to apply energy to water molecules present inside the amniotic membrane and cause drying during a pressure recovery operation that slightly raises the pressure inside the depressurized processing tank (10) toward atmospheric pressure.

Abstract: A polymerizable composition for optical material including two or more different monomers for optical material and a polymerization catalyst, in which the content of the polymerization catalyst relative to the total amount of the monomers for optical material is from 0.1150 to 0.2000 parts by mass, the viscosity of the polymerizable composition for optical material is from 10 mPa·s to 1000 mPa·s as measured with a B-type viscometer at 20° C. and 60 rpm, and at least one of the two or more different monomers for optical material is an episulfide compound.

Abstract: A polymerizable composition for an optical material containing two or more different monomers for an optical material, and a polymerization catalyst, in which at least one of the two or more different monomers for an optical material is an isocyanate compound containing an aromatic ring, a content of the polymerization catalyst with respect to a total of 100 parts by mass of the two or more different monomers for an optical material is from 0.010 parts by mass to 0.50 parts by mass, and the viscosity measured by a B-type viscometer at 25° C. and 60 rpm is from 10 mPa·s to 1,000 mPa·s.

Abstract: A polymerizable composition for an optical material containing two or more different monomers for an optical material, and a polymerization catalyst, in which at least one of the two or more different monomers for an optical material is an isocyanate compound containing no aromatic rings, a content of the polymerization catalyst with respect to a total of 100 parts by mass of the two or more different monomers for an optical material is from more than 0.05 parts by mass to 2.0 parts by mass, and a viscosity measured by a B-type viscometer at 25° C. and 60 rpm is from 10 mPa·s to 1,000 mPa·s.

Abstract: A polymerizable composition for an optical material containing two or more different monomers for an optical material, and a polymerization catalyst, in which at least one of the two or more different monomers for an optical material is an isocyanate compound containing no aromatic rings, a content of the polymerization catalyst with respect to a total of 100 parts by mass of the two or more different monomers for an optical material is from more than 0.05 parts by mass to 2.0 parts by mass, and a viscosity measured by a B-type viscometer at 25° C. and 60 rpm is from 10 mPa·s to 1,000 mPa·s.

Abstract: Provided is a benzotriazole compound represented by Formula (1). In Formula (1), R1 to R4 represent substituents. In Formula (1), n1 represents an integer from 0 to 4, and n2 represents an integer from 0 to 3.

Abstract: A polymerizable composition for an optical material containing two or more different monomers for an optical material, and a polymerization catalyst, in which at least one of the two or more different monomers for an optical material is an isocyanate compound containing an aromatic ring, a content of the polymerization catalyst with respect to a total of 100 parts by mass of the two or more different monomers for an optical material is from 0.010 parts by mass to 0.50 parts by mass, and the viscosity measured by a B-type viscometer at 25° C. and 60 rpm is from 10 mPa·s to 1,000 mPa·s.

Abstract: A polymerizable composition for an optical material includes a compound represented by General Formula (1) and a polymerization reactive compound.

Abstract: The polymerizable composition for an optical material of the present invention includes a compound (A) represented by General Formula (a) and including two or more allyloxycarbonyl groups, at least one kind of radical polymerization initiator (B) selected from the group consisting of a peroxyketal-based radical polymerization initiator, a peroxymonocarbonate-based radical polymerization initiator, and a peroxyester-based radical polymerization initiator, and a modifier (C) selected from a polyether modified siloxane compound represented by General Formula (c1) or a polyol compound represented by General Formula (c2).

Abstract: A method of manufacturing an optical member by curing a thermally polymerizable composition by heating includes, in the following order: a first step of filling an inside of a mold with the thermally polymerizable composition in which the mold is configured by disposing a frame-shaped member, with a Young's modulus of 1.0 GPa or more at a polymerization initiation temperature of the thermally polymerizable composition, between two mold members facing each other; and a second step of heating the mold to the polymerization initiation temperature or more.

Abstract: A polymerizable composition for an optical material of the present disclosure includes (A) an isocyanate compound, (B) at least one active hydrogen compound selected from the group consisting of a polythiol compound having two or more mercapto groups, a hydroxythiol compound having one or more mercapto groups and one or more hydroxyl groups, a polyol compound having two or more hydroxyl groups, and an amine compound, and (C) an ultraviolet absorber represented by General Formula (1).

Abstract: A polymerizable composition for an optical material according to the present invention includes one or two or more compounds selected from the group consisting of component (A): an ester compound having a specific structure and component (B): an ether compound having a specific structure, and a polymerizable compound.

Abstract: An injection molding apparatus includes a substantially circular first substrate, a substantially circular second substrate disposed to face a surface of the first substrate, a fixing member which fixes a peripheral end portion of the first substrate and a peripheral end portion of the second substrate, and an injection portion which is provided in the fixing member and from which a composition is injected into a gap between the first substrate and the second substrate, in which a space connecting with the injection portion and the gap is provided in at least a part of a periphery of the gap, and a width of the space in a thickness direction is larger than a width of the gap in the thickness direction.

Abstract: A polymerizable composition for optical materials of the present invention contains (A) a polyisocyanate compound, (B) a polythiol compound, (C) a photochromic compound, (D) a polyether compound having a number-average molecular weight of 50 to 10,000, and (E) a polyether-modified siloxane compound having a viscosity of 1 mPa·s or more and less than 1,600 mPa·s.

Abstract: In an optical material of the disclosure, a transmittance curve satisfies the following characteristic (1) and a luminous transmittance satisfies the following characteristic (2), the transmittance curve and the luminous transmittance being measured at a thickness of 2 mm, (1) a maximum transmittance at a wavelength of from 410 nm to 450 nm is from 20% to 65%, and (2) the luminous transmittance is from 70% to 85%.

Abstract: In an optical material, a transmittance curve satisfies the following characteristics (1) and (2) and a hue in the CIE 1976 (L*, a*, b*) color space satisfies the following characteristic (3), (1) the transmittance curve has a maximum value of a transmittance at a wavelength of from 400 nm to 450 nm or from 520 nm to 570 nm, and a largest value of the transmittance at the wavelength of from 400 nm to 450 nm and a transmittance at from 520 nm to 570 nm are 50% or more, (2) the transmittance curve has a minimum value of a transmittance at a wavelength of from 470 nm to 500 nm, and the minimum value is 40% or less, and (3) in the hue in the CIE 1976 (L*, a*, b*) color space, a* is from 2.5 to 5.5 and b* is from 5 to 25.