Abstract: Provided is a benzotriazole compound represented by Formula (1). In Formula (1), R1 to R4 represent substituents. In Formula (1), n1 represents an integer from 0 to 4, and n2 represents an integer from 0 to 3.

Abstract: A method for setting polymerization condition includes a physical property acquiring step of, when heating a composition including a polymerization-reactive compound and a polymerization catalyst and/or a polymerization initiator and retaining heat at a predetermined temperature, acquiring a physical property value a derived from a functional group before heating of the polymerization-reactive compound and a physical property value b derived from a remaining functional group after maintaining a temperature for a predetermined time; a remaining functional group ratio calculating step of calculating a remaining functional group ratio from the physical property value a and the physical property value b; a reaction rate coefficient calculating step of calculating a reaction rate coefficient from the remaining functional group ratio on the basis of a reaction rate equation; and a polymerization temperature calculating step of calculating a polymerization temperature on the basis of the reaction rate coefficient an

Abstract: A polymerizable composition for optical materials of the present invention contains (A) a polyisocyanate compound, (B) a polythiol compound, (C) a photochromic compound, (D) a polyether compound having a number-average molecular weight of 50 to 10,000, and (E) a polyether-modified siloxane compound having a viscosity of 1 mPa·s or more and less than 1,600 mPa·s.

Abstract: A molded product of the present invention includes a polythiourethane, in which an SH group concentration according to an IR analysis method is 0.30 wt % to 3.0 wt %.

Abstract: A method of producing an optical member includes: a first step of using a mold member and a substrate provided with a depressed portion including a bottom portion and an opening, to place the mold member at the opening, thereby defining a space between the depressed portion and the mold member; a second step of placing, in the space, a polymerizable composition containing a monomer for an optical material; and a third step of curing the monomer for an optical material in the polymerizable composition, thereby obtaining a cured product of the polymerizable composition. The opening of the depressed portion has a larger area than the area of the bottom portion.

Abstract: A method of manufacturing an optical member by curing a thermally polymerizable composition by heating includes, in the following order: a first step of filling an inside of a mold with the thermally polymerizable composition in which the mold is configured by disposing a frame-shaped member, with a Young's modulus of 1.0 GPa or more at a polymerization initiation temperature of the thermally polymerizable composition, between two mold members facing each other; and a second step of heating the mold to the polymerization initiation temperature or more.

Abstract: In an optical material, a transmittance curve satisfies the following characteristics (1) and (2) and a hue in the CIE 1976 (L*, a*, b*) color space satisfies the following characteristic (3), (1) the transmittance curve has a maximum value of a transmittance at a wavelength of from 400 nm to 450 nm or from 520 nm to 570 nm, and a largest value of the transmittance at the wavelength of from 400 nm to 450 nm and a transmittance at from 520 nm to 570 nm are 50% or more, (2) the transmittance curve has a minimum value of a transmittance at a wavelength of from 470 nm to 500 nm, and the minimum value is 40% or less, and (3) in the hue in the CIE 1976 (L*, a*, b*) color space, a* is from 2.5 to 5.5 and b* is from 5 to 25.

Abstract: A lens ordering system includes: a computer, the computer being provided with a CPU, a storage unit, and a selection unit that is configured to be controlled by the CPU. The storage unit stores data, configured to enable determination of lens information that includes a resin material type, a pigment type, and a coating type that are used for a lens material, based on user information that includes basic information pertaining to a user, and at least one of usage information pertaining to lens usage desired by the user or psychosomatic information including psychosomatic symptoms and conditions including the eyes of the user. The selection unit determines and outputs the lens information based on the user information acquired pertaining to the user and the data stored in the storage unit.

Abstract: An injection molding apparatus includes a substantially circular first substrate, a substantially circular second substrate disposed to face a surface of the first substrate, a fixing member which fixes a peripheral end portion of the first substrate and a peripheral end portion of the second substrate, and an injection portion which is provided in the fixing member and from which a composition is injected into a gap between the first substrate and the second substrate, in which a space connecting with the injection portion and the gap is provided in at least a part of a periphery of the gap, and a width of the space in a thickness direction is larger than a width of the gap in the thickness direction.

Abstract: Sortilin is a sorting receptor that directs target proteins to the secretary or endocytic compartments of cells that is found in both extracellular vesicles and cells. Provided herein are methods and compositions for decreasing or inhibiting trafficking of sortilin to an extracellular vesicle, for example by inhibiting the formation of intermolecular sortilin dimers.

Abstract: A method for manufacturing a photochromic lens includes: a step of injecting a polymerizable composition through an injection part in an injection molding apparatus and filling a gap with the polymerizable composition through a space; a step of heating the filled polymerizable composition to be polymerized and cured and forming a photochromic layer on a resin substrate; and a step of taking out a resulting laminate composed of the resin substrate and the photochromic layer, in which the polymerizable composition includes an isocyanate compound, a thiol compound, a polyol compound, and a photochromic compound.

Abstract: A polymerizable composition for an optical material of the present invention includes (A) a compound of which pKa value is 1 to 9, (B) a di- or higher functional iso(thio)cyanate compound, and (C) a di- or higher functional active hydrogen compound.

Abstract: Sortilin is a sorting receptor that directs target proteins to the secretary or endocytic compartments of cells that is found in both extracellular vesicles and cells. Provided herein are methods and compositions for decreasing or inhibiting trafficking of sortilin to an extracellular vesicle, for example by inhibiting the formation of intermolecular sortilin dimers.

Abstract: A polymerizable composition for an optical material containing two or more different monomers for an optical material, and a polymerization catalyst, in which at least one of the two or more different monomers for an optical material is an isocyanate compound containing an aromatic ring, a content of the polymerization catalyst with respect to a total of 100 parts by mass of the two or more different monomers for an optical material is from 0.010 parts by mass to 0.50 parts by mass, and the viscosity measured by a B-type viscometer at 25° C. and 60 rpm is from 10 mPa·s to 1,000 mPa·s.

Abstract: The present invention addresses the problem of providing a material as a scaffold used to prevent poor skin grafting when there is a defect in the perichondrium or periosteum or a defect in subcutaneous tissue. As a solution, there is provided a dry amniotic membrane manufactured according to a specific drying process. In more detail, a raw amniotic membrane placed in a processing tank (10) is continuously heated by a far-infrared heater (14) provided inside the processing tank (10), while performing a decompression operation where the interior of the processing tank (10) is placed in a decompressed state and irradiation of the raw amniotic membrane with microwaves from a microwave generating device (30) provided inside the processing tank (10) to apply energy to water molecules present inside the amniotic membrane and cause drying during a pressure recovery operation that slightly raises the pressure inside the depressurized processing tank (10) toward atmospheric pressure.

Abstract: A polymerizable composition for optical material including two or more different monomers for optical material and a polymerization catalyst, in which the content of the polymerization catalyst relative to the total amount of the monomers for optical material is from 0.1150 to 0.2000 parts by mass, the viscosity of the polymerizable composition for optical material is from 10 mPa·s to 1000 mPa·s as measured with a B-type viscometer at 20° C. and 60 rpm, and at least one of the two or more different monomers for optical material is an episulfide compound.

Abstract: A polymerizable composition for an optical material containing two or more different monomers for an optical material, and a polymerization catalyst, in which at least one of the two or more different monomers for an optical material is an isocyanate compound containing no aromatic rings, a content of the polymerization catalyst with respect to a total of 100 parts by mass of the two or more different monomers for an optical material is from more than 0.05 parts by mass to 2.0 parts by mass, and a viscosity measured by a B-type viscometer at 25° C. and 60 rpm is from 10 mPa·s to 1,000 mPa·s.

Abstract: A polymerizable composition for an optical material containing two or more different monomers for an optical material, and a polymerization catalyst, in which at least one of the two or more different monomers for an optical material is an isocyanate compound containing an aromatic ring, a content of the polymerization catalyst with respect to a total of 100 parts by mass of the two or more different monomers for an optical material is from 0.010 parts by mass to 0.50 parts by mass, and the viscosity measured by a B-type viscometer at 25° C. and 60 rpm is from 10 mPa·s to 1,000 mPa·s.

Abstract: A polymerizable composition for an optical material containing two or more different monomers for an optical material, and a polymerization catalyst, in which at least one of the two or more different monomers for an optical material is an isocyanate compound containing no aromatic rings, a content of the polymerization catalyst with respect to a total of 100 parts by mass of the two or more different monomers for an optical material is from more than 0.05 parts by mass to 2.0 parts by mass, and a viscosity measured by a B-type viscometer at 25° C. and 60 rpm is from 10 mPa·s to 1,000 mPa·s.

Abstract: Provided is a benzotriazole compound represented by Formula (1). In Formula (1), R1 to R4 represent substituents. In Formula (1), n1 represents an integer from 0 to 4, and n2 represents an integer from 0 to 3.