Patents by Inventor Shinsuke Ooike

Shinsuke Ooike has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antitumor agent
    Patent number: 9125915
    Abstract: The invention provides a method of inhibiting binding between acetylated histone and a bromodomain-containing protein in a mammal, as well as a method of shrinking or killing of cancer cells expressing a bromodomain-containing protein or inhibiting the growth of cancer cells expressing a bromodomain-containing protein in a mammal. The methods involve administering an effective amount of (S)-2-[4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-(4-hydroxyphenyl)acetamide or a dihydrate thereof to the mammal.
    Type: Grant
    Filed: May 28, 2013
    Date of Patent: September 8, 2015
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Shinji Miyoshi, Shinsuke Ooike, Kazunori Iwata, Hidemasa Hikawa, Kunio Sugahara
  • Antitumor agent
    Patent number: 8476260
    Abstract: The present invention relates to a novel antitumor agent containing a compound that inhibits binding between acetylated histone and a bromodomain-containing protein, preferably a thienotriazolodiazepine compound represented by the following formula (I) wherein each symbol is as defined in the description, or a pharmaceutically acceptable salt thereof or a hydrate or solvate as an active ingredient.
    Type: Grant
    Filed: December 26, 2008
    Date of Patent: July 2, 2013
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Shinji Miyoshi, Shinsuke Ooike, Kazunori Iwata, Hidemasa Hikawa, Kunio Sugahara
  • Cyanopyridine derivative and use thereof as medicine
    Patent number: 7928126
    Abstract: A therapeutic drug for cancer containing a substance selected from the group consisting of a novel cyanopyridine derivative, a pharmaceutically acceptable salt, a hydrate, a water adduct and a solvate as an active ingredient can be provided.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: April 19, 2011
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Masahiko Morioka, Hiroshi Ikegami, Makoto Sakiyama, Masayuki Hayashi, Shinsuke Ooike, Yasuhiro Fujino, Daisuke Abe, Hideo Tomozane
  • ANTITUMOR AGENT
    Publication number: 20100286127
    Abstract: The present invention relates to a novel antitumor agent containing a compound that inhibits binding between acetylated histone and a bromodomain-containing protein, preferably a thienotriazolodiazepine compound represented by the following formula (I) wherein each symbol is as defined in the description, or a pharmaceutically acceptable salt thereof or a hydrate or solvate as an active ingredient.
    Type: Application
    Filed: December 26, 2008
    Publication date: November 11, 2010
    Applicant: MITSUBISHI TANABE PHARMA CORPORATION
    Inventors: Shinji Miyoshi, Shinsuke Ooike, Kazunori Iwata, Hidemasa Hikawa, Kunio Sugahara
  • Cyanopyridine derivative and use thereof as medicine
    Publication number: 20090292121
    Abstract: A therapeutic drug for cancer containing a substance selected from the group consisting of a novel cyanopyridine derivative, a pharmaceutically acceptable salt, a hydrate, a water adduct and a solvate as an active ingredient can be provided.
    Type: Application
    Filed: April 28, 2006
    Publication date: November 26, 2009
    Inventors: Masahiko Morioka, Hiroshi Ikegami, Makoto Sakiyama, Masayuki Hayashi, Shinsuke Ooike, Yasuhiro Fujino, Daisuke Abe, Hideo Tomozane