Abstract: An outboard motor includes an engine, a fuel pump to draw fuel into an outboard motor body from a fuel tank installed on a hull, a temporary storage tank to temporarily store the fuel drawn into the outboard motor body by the fuel pump, a fuel injector to inject the fuel stored in the temporary storage tank into the engine, a temperature sensor on the temporary storage tank to detect a temperature of the fuel stored in the temporary storage tank, and a controller configured or programmed to perform a control to limit an engine speed to no more than a predetermined upper limit rotation speed based on a detection result of the temperature sensor while the engine is running.

Abstract: A congestion prediction device, a congestion prediction method, and a storage medium are provided. A mapping outputs an output variable when input variables are input to the mapping. The output variable indicates a degree of congestion in a predetermined specific area. The mapping is learned in advance by machine learning. The input variables include congestion variables. Each of the congestion variables indicates a degree of congestion in the specific area at regular time intervals within a specific period. The output variable indicates a degree of congestion after a lapse of the regular time interval from an end time of the specific period.

Abstract: An example object of the invention is to provide a binding nucleic acid molecule capable of specifically binding to a SARS-CoV-2 spike glycoprotein.

Abstract: The present invention provides a method for producing a nucleic acid molecule that can obtain a nucleic acid molecule that binds to a target and does not inhibit a function of the target. The production method for a nucleic acid molecule of the present invention is a method for producing a nucleic acid molecule that binds to a first biological molecule and does not inhibit a function of the first biological molecule, the method including the steps of: (A) bringing a candidate nucleic acid molecule into contact with the first biological molecule to select a nucleic acid molecule that has bound to the first biological molecule as a first selected nucleic acid molecule; and (B) selecting the first selected nucleic acid molecule as an intended nucleic acid molecule.

Abstract: Provided is a sliding bearing having an improved circularity and having achieved an increase in contact area with respect to a holder. The sliding bearing 1 comprises a pair of an upper halved member 2 and a lower halved member 3 which are portions of a cylinder halved in parallel to an axial direction. The sliding bearing has an oil hole 24 penetrating therethrough in a direction orthogonal to the axial direction of the cylinder. An inner peripheral portion 24a of the oil hole 24 has formed a laser-melted portion 25 which is an area in which a change in property in comparison to the original material has been caused by the thermal influence of laser.

Abstract: Provided is a sliding bearing that can improve contact with a holder on a bearing rear surface and improve material yield. This sliding bearing comprises a pair of upper and lower half split members which are formed by bisecting a cylinder in a direction parallel to the axial direction thereof, the sliding bearing having hardened sections on the end faces of the upper half split member in the cylinder axial direction and hardened sections on the end faces of the lower half split member in the cylinder axial direction. The hardened sections are laser modified sections in which the properties of the material have been changed by the thermal influence of a laser.

Abstract: Provided is a sliding bearing having an improved circularity and having achieved an increase in contact area with respect to a holder. The sliding bearing 1 comprises a pair of an upper halved member 2 and a lower halved member 3 which are portions of a cylinder halved in parallel to an axial direction. The sliding bearing has an oil hole 24 penetrating therethrough in a direction orthogonal to the axial direction of the cylinder. An inner peripheral portion 24a of the oil hole 24 has formed a laser-melted portion 25 which is an area in which a change in property in comparison to the original material has been caused by the thermal influence of laser.

Abstract: An all-wheel-drive-vehicle controller includes: a drive gear coupled to a driving source; a driven gear meshed with the drive gear and coupled to main and sub driving-wheel axle shafts transmitting torques to main and sub driving wheels, respectively; a transfer clutch interposed between the driven gear and the sub-driving-wheel axle shaft and adjusting the torque transmitted to the sub driving wheel; a first determination unit determining whether a first condition in which a torque applied to the drive gear is substantially zero is satisfied; a second determination unit determining whether a second condition in which hydraulic pressure is applied to the transfer clutch and a torque applied to the driven gear is substantially zero is satisfied; and a control unit controlling a torque adjuster to adjust the torque applied to either one of the drive gear and the driven gear if the first and second conditions are satisfied.

Abstract: Methods and computer methods used to assess an individual for the prediction of risk of developing a Cardiovascular (CV) Event over a 1 to 5 year period are provided. The methods employ at least two biomarkers selected from MMP12, angiopoietin-2, complement C7, cardiac troponin I, angiopoietin-related protein 4, CCL18/PARC, alpha-1-antichymotrypsin complex, GDF11 and alpha-2-antiplasmin, or GDF11 in combination with FSTL3. The methods are particularly useful in predicting CV events in patients who suffer from coronary heart disease (CHD).

Abstract: An all-wheel-drive-vehicle controller includes: a drive gear coupled to a driving source; a driven gear meshed with the drive gear and coupled to main and sub driving-wheel axle shafts transmitting torques to main and sub driving wheels, respectively; a transfer clutch interposed between the driven gear and the sub-driving-wheel axle shaft and adjusting the torque transmitted to the sub driving wheel; a first determination unit determining whether a first condition in which a torque applied to the drive gear is substantially zero is satisfied; a second determination unit determining whether a second condition in which hydraulic pressure is applied to the transfer clutch and a torque applied to the driven gear is substantially zero is satisfied; and a control unit controlling a torque adjuster to adjust the torque applied to either one of the drive gear and the driven gear if the first and second conditions are satisfied.

Abstract: Methods and computer methods used to assess an individual for the prediction of risk of developing a Cardiovascular (CV) Event over a 1 to 5 year period are provided. The methods employ at least two biomarkers selected from MMP12, angiopoietin-2, complement C7, cardiac troponin I, angiopoietin-related protein 4, CCL18/PARC, alpha-1-antichymotrypsin complex, GDF11 and alpha-2-antiplasmin, or GDF11 in combination with FSTL3. The methods are particularly useful in predicting CV events in patients who suffer from coronary heart disease (CHD).

Abstract: The present invention provides a novel sensor for detecting streptavidin (SA). The nucleic acid sensor for analyzing SA of the present invention includes the following nucleic acid element that includes a catalyst nucleic acid molecule (D) that exerts a catalytic function and a binding nucleic acid molecule (A) that binds to SA. The nucleic acid element is a double-stranded nucleic acid element including a first strand and a second strand. The first strand (ss1) includes the binding nucleic acid molecule (A), a loop-forming sequence (L1), and the catalyst nucleic acid molecule (D) linked in this order. The second strand (ss2) includes a stem-forming sequence (SA), a loop-forming sequence (L2), and a stem-forming sequence (SD) linked in this order.

Abstract: Biomarkers, methods, devices, reagents, systems, and kits used to assess an individual for the prediction of risk of developing a Cardiovascular (CV) Event over a 1 to 5 year period are provided.

Abstract: The subject disclosure concerns methods for evaluation of renal cell carcinoma (RCC). Such methods include a method of determining of a diagnosis of the individual as having or not having RCC; determination of a prognosis of a future course of RCC; determination of disease burden; or determination of recurrence of RCC in an individual who had been apparently cured of RCC. The methods each involve the detection of the value of at least one biomarker of Table 1. The biomarker value is used, in some of the methods, to determine whether the individual does or does not demonstrate evidence of disease, and in another method, to determine the degree or a score indicative of the individual's extent of disease.

Abstract: The present invention provides a novel sensor for detecting streptavidin (SA). The nucleic acid sensor for analyzing SA of the present invention includes the following nucleic acid element that includes a catalyst nucleic acid molecule (D) that exerts a catalytic function and a binding nucleic acid molecule (A) that binds to SA. The nucleic acid element is a double-stranded nucleic acid element including a first strand and a second strand. The first strand (ss1) includes the binding nucleic acid molecule (A), a loop-forming sequence (L1), and the catalyst nucleic acid molecule (D) linked in this order. The second strand (ss2) includes a stem-forming sequence (SA), a loop-forming sequence (L2), and a stem-forming sequence (SD) linked in this order.

Abstract: The subject disclosure concerns methods for evaluation of renal cell carcinoma (RCC). Such methods include a method of determining of a diagnosis of the individual as having or not having RCC; determination of a prognosis of a future course of RCC; determination of disease burden; or determination of recurrence of RCC in an individual who had been apparently cured of RCC. The methods each involve the detection of the value of at least one biomarker of Table 1. The biomarker value is used, in some of the methods, to determine whether the individual does or does not demonstrate evidence of disease, and in another method, to determine the degree or a score indicative of the individual's extent of disease.