Abstract: A surgery assistance device includes an arm that holds an endoscope and adjusts a position of the endoscope, a measuring device having a fixed position relative to the endoscope, the measuring device measuring a distance to a surgery target region of a subject, and a control device configured to obtain a positional relationship between the surgery target region of the subject and a distal end portion of the endoscope based on information from the measuring device, generate a map image showing the position of the endoscope on a three-dimensional model of the surgery target region by using the positional relationship, and transmit display information for displaying the map image.

Abstract: A surgical device retracting mechanism includes a holder that holds a surgical device, a guide that guides the holder to linearly advance and retract, a locking member that locks the holder in a locking state in which the surgical device is inserted in a surgical site, and a retracting device that releases the locking state and retract the holder based on a detection signal.

Abstract: An intraocular surgery instrument holder (1) including a translational driving unit (2) as a driving mechanism configured to be capable of movement with multiple degrees of freedom, an arm unit (3) as a passive motion mechanism coupled with the translational driving unit (2) and configured to be capable of movement with multiple degrees of freedom, and a surgical instrument holding unit (4) as a passive gimbal mechanism coupled with one end of the arm unit (3), and configured to hold an intraocular surgery instrument, and to be capable of movement with a degree of rotational freedom with an opening part of a hole in an eyeball for insertion of the intraocular surgery instrument being a fixed point. A brake mechanism for inhibiting movement of the arm unit (3) is provided to the arm unit (3).

Abstract: Disclosed herein is a prophylactic or therapeutic agent for ocular fundus disease, especially diabetic retinopathy or age-related macular degeneration. The prophylactic or therapeutic agent for ocular fundus disease comprising: (S)-(?)-1-(4-fluoro-5-isoquinolinesulfonyl)-2-methyl-1,4-homopiperazine, a salt thereof, or a solvate thereof, as an active ingredient.

Abstract: Disclosed herein is a prophylactic or therapeutic agent for ocular fundus disease, especially diabetic retinopathy or age-related macular degeneration. The prophylactic or therapeutic agent for ocular fundus disease comprising: (S)-(?)-1-(4-fluoro-5-isoquinolinesulfonyl)-2-methyl-1,4-homopiperazine, a salt thereof, or a solvate thereof, as an active ingredient.

Abstract: Disclosed herein is a prophylactic or therapeutic agent for ocular fundus disease, especially diabetic retinopathy or age-related macular degeneration. The prophylactic or therapeutic agent for ocular fundus disease comprising: (S)-(?)-1-(4-fluoro-5-isoquinolinesulfonyl)-2-methyl-1,4-homopiperazine, a salt thereof, or a solvate thereof, as an active ingredient.

Abstract: Disclosed herein is a prophylactic or therapeutic agent for ocular fundus disease, especially diabetic retinopathy or age-related macular degeneration. The prophylactic or therapeutic agent for ocular fundus disease comprising: (S)-(?)-1-(4-fluoro-5-isoquinolinesulfonyl)-2-methyl-1,4-homopiperazine, a salt thereof, or a solvate thereof, as an active ingredient.

Abstract: Disclosed herein is a prophylactic or therapeutic agent for ocular fundus disease, especially diabetic retinopathy or age-related macular degeneration. The prophylactic or therapeutic agent for ocular fundus disease comprising: (S)-(?)-1-(4-fluoro-5-isoquinolinesulfonyl)-2-methyl-1,4-homopiperazine, a salt thereof, or a solvate thereof, as an active ingredient.