Patents by Inventor Shinu John

Shinu John has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Herpes simplex virus vaccine
    Patent number: 11752206
    Abstract: Herpes simplex virus (HSV) ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines. In a preferred embodiment, the vaccine is formulated as a lipid nanoparticle comprising at least one cationic lipid.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: September 12, 2023
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John, Andrew J. Bett, Danilo R. Casimiro, Dai Wang, Lan Zhang
  • HUMAN CYTOMEGALOVIRUS RNA VACCINES
    Publication number: 20230116376
    Abstract: The disclosure describes HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: August 12, 2022
    Publication date: April 13, 2023
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John, Kambiz Mousavi
  • HUMAN CYTOMEGALOVIRUS VACCINE
    Publication number: 20230044692
    Abstract: The disclosure relates to HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: June 13, 2022
    Publication date: February 9, 2023
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John
  • Human cytomegalovirus vaccine
    Patent number: 11541113
    Abstract: The disclosure relates to HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Grant
    Filed: December 10, 2021
    Date of Patent: January 3, 2023
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John
  • HUMAN CYTOMEGALOVIRUS VACCINE
    Publication number: 20220401551
    Abstract: Aspects of the disclosure relate to methods for producing an antigen-specific immune response to human cytomegalovirus (hCMV) in a subject by administering mRNA vaccines.
    Type: Application
    Filed: June 14, 2022
    Publication date: December 22, 2022
    Applicant: ModernaTX, Inc.
    Inventors: Jack F. Kramarczyk, Kimberly Hassett, Shinu John, Phil White, Andrea Carfi
  • HUMAN CYTOMEGALOVIRUS VACCINE
    Publication number: 20220347292
    Abstract: Aspects of the invention relate to methods for producing an antigen-specific immune response to human cytomegalovirus (hCMV) in a subject by administering mRNA vaccines comprising hCMV antigenic polypeptides gH, gL, UL128, UL130, UL131 A and gB formulated in lipid nanoparticles, wherein the antigen-specific immune response to hCMV results in neutralizing antibodies that have i) a geometric mean titer of at least 3-fold against epithelial cell infection or ii) a geometric mean ratio of 9-41 against epithelial cell infection or iii) a geometric mean ratio of 4-8-fold against fibroblast infection.
    Type: Application
    Filed: September 11, 2020
    Publication date: November 3, 2022
    Applicant: ModernaTX, Inc.
    Inventors: Lori Panther, Shinu John, Tal Zaks
  • Human cytomegalovirus RNA vaccines
    Patent number: 11484590
    Abstract: The disclosure describes HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: November 1, 2022
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John, Kambiz Mousavi
  • Human cytomegalovirus vaccine
    Patent number: 11406703
    Abstract: Aspects of the disclosure relate to methods for producing an antigen-specific immune response to human cytomegalovirus (hCMV) in a subject by administering mRNA vaccines.
    Type: Grant
    Filed: August 25, 2021
    Date of Patent: August 9, 2022
    Assignee: ModernaTX, Inc.
    Inventors: Jack F. Kramarczyk, Kimberly Hassett, Shinu John, Phil White, Andrea Carfi
  • HUMAN CYTOMEGALOVIRUS VACCINE
    Publication number: 20220096626
    Abstract: The disclosure relates to HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: December 10, 2021
    Publication date: March 31, 2022
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John
  • HUMAN CYTOMEGALOVIRUS VACCINE
    Publication number: 20220062408
    Abstract: Aspects of the disclosure relate to methods for producing an antigen-specific immune response to human cytomegalovirus (hCMV) in a subject by administering mRNA vaccines.
    Type: Application
    Filed: August 25, 2021
    Publication date: March 3, 2022
    Applicant: ModernaTX, Inc.
    Inventors: Jack F. Kramarczyk, Kimberly Hassett, Shinu John, Phil White, Andrea Carfi
  • Human cytomegalovirus vaccine
    Patent number: 11197927
    Abstract: The disclosure relates to HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: December 14, 2021
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John
  • HUMAN CYTOMEGALOVIRUS VACCINE
    Publication number: 20200338190
    Abstract: The disclosure relates to HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: May 1, 2020
    Publication date: October 29, 2020
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John
  • EPSTEIN-BARR VIRUS VACCINES
    Publication number: 20200282047
    Abstract: The disclosure relates to EBV ribonucleic acid vaccines as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: November 20, 2018
    Publication date: September 10, 2020
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John, Elisabeth Narayanan, Brooke Bollman
  • HUMAN CYTOMEGALOVIRUS RNA VACCINES
    Publication number: 20200246453
    Abstract: The disclosure describes HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: March 27, 2020
    Publication date: August 6, 2020
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John, Kambiz Mousavi
  • Human cytomegalovirus RNA vaccines
    Patent number: 10716846
    Abstract: The disclosure describes HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: July 21, 2020
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John, Kambiz Mousavi
  • Human cytomegalovirus vaccine
    Patent number: 10695419
    Abstract: The disclosure relates to HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: June 30, 2020
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John
  • HERPES SIMPLEX VIRUS VACCINE
    Publication number: 20200129615
    Abstract: The disclosure relates to herpes simplex virus (HSV) ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines. In a preferred embodiment, the vaccine is formulated as a lipid nanoparticle comprising at least one cationic lipid.
    Type: Application
    Filed: March 15, 2018
    Publication date: April 30, 2020
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John, Andrew J. Bett, Danilo R. Casimiro, Dai Wang, Lan Zhang
  • HERPES SIMPLEX VIRUS VACCINE
    Publication number: 20200054737
    Abstract: The disclosure relates to herpes simplex virus (HSV) ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: April 25, 2018
    Publication date: February 20, 2020
    Applicant: Modema TX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John, Andrew J. Bett, Danilo R. Casimiro, Dai Wang, Lan Zhang
  • HUMAN CYTOMEGALOVIRUS RNA VACCINES
    Publication number: 20190321464
    Abstract: The disclosure describes HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: June 24, 2019
    Publication date: October 24, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John, Kambiz Mousavi
  • HUMAN CYTOMEGALOVIRUS VACCINE
    Publication number: 20190314493
    Abstract: The disclosure relates to HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: April 19, 2019
    Publication date: October 17, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John