Abstract: The present invention provides mammalian cell expression vectors that impart to mammalian host cells an ability to produce high levels of foreign gene-derived proteins. A ubiquitously acting chromatin opening element (UCOE) is introduced into an expression vector that has a plasmid DNA integrated into a transcriptional hot spot on the chromosome of a dihydrofolate reductase gene-deficient host cell so that it allows for selection of strains that grow in hypoxanthine-thymidine (hereinafter denoted as HT)-free medium, whereby transformants will produce a protein of interest in increased amounts.

Abstract: According to one embodiment, a horizontal compressor comprises a container accommodating a compression mechanism unit and an electric motor unit, a first leg fixed to the container near the motor unit, a second leg fixed to an end of the container on the compression mechanism unit side, an accumulator between the legs, and a joint port in the container. The second leg includes a first support portion supporting the container in a horizontal attitude, and a second support portion supporting the container standing in a vertical attitude. The first support portion extends in a direction away from the joint port relative to the second support portion.

Abstract: An industrial vehicle remote control system includes a forklift that has a vehicle communication unit and a remote control device that has a remote communication unit and is used to remotely control the forklift. A vehicle wireless CPU of the industrial vehicle remote control system acquires the received radio wave intensity of a remote control signal by which the two communication units wirelessly communicate, and, on the basis of the results thereof, determines whether the forklift is positioned in a permission range or in a prohibition range.

Abstract: An industrial vehicle remote operation system includes an industrial vehicle including a vehicle communication portion, a communication device, and, a first signal conversion portion. The communication device includes a reception portion that receives two or more types of operation signals, an obtainment portion that obtains a conversion program for converting the operation signal into the remote instruction signal, a storage portion configured to store the conversion program, a second signal conversion portion configured to convert the operation signal into the remote instruction signal using the conversion program, and a communication device communication portion that sends the remote instruction signal to the vehicle communication portion. The communication device includes an update portion configured to update information stored in the storage portion so as to enable addition, deletion, or change of one or more of the operation signals that are convertible by the second signal conversion portion.

Abstract: The present invention provides mammalian cell expression vectors that impart to mammalian host cells an ability to produce high levels of foreign gene-derived proteins. A ubiquitously acting chromatin opening element (UCOE) is introduced into an expression vector that has a plasmid DNA integrated into a transcriptional hot spot on the chromosome of a dihydrofolate reductase gene-deficient host cell so that it allows for selection of strains that grow in hypoxanthine-thymidine (hereinafter denoted as HT)-free medium, whereby transformants will produce a protein of interest in increased amounts.

Abstract: According to one embodiment, a horizontal compressor comprises a container accommodating a compression mechanism unit and an electric motor unit, a first leg fixed to the container near the motor unit, a second leg fixed to an end of the container on the compression mechanism unit side, an accumulator between the legs, and a joint port in the container. The second leg includes a first support portion supporting the container in a horizontal attitude, and a second support portion supporting the container standing in a vertical attitude. The first support portion extends in a direction away from the joint port relative to the second support portion.

Abstract: An editing apparatus includes a processor and a memory. The processor performs processes. The processes include causing a print image to be displayed in a first area, and a mark and at least one portion of a target character string to be displayed in a second area. The processes include causing a selection image to be displayed in a third area. The processes include performing a first determination whether a corresponding block included in the print image overlaps with the selection image. The processes include causing the entire corresponding block to be displayed in a first residual area. The processes include performing a second determination whether the mark overlaps with the selection image. The processes include reducing a size of the target character string. The processes include causing the mark and at least one portion of a reduced character string to be displayed in a second residual area.

Abstract: The present invention provides a novel therapeutic strategy using an inhibitor targeting PD-1/PD-L1. A pharmaceutical composition which comprises a COX-2 inhibitor and is administered before, after or simultaneously with the administration of an inhibitor targeting PD-1/PD-L1. A potentiator for the immunostimulatory effect of an inhibitor targeting PD-1/PD-L1, which comprises a COX-2 inhibitor.

Abstract: An industrial vehicle remote control system includes a forklift that has a vehicle communication unit and a remote control device that has a remote communication unit and is used to remotely control the forklift. A vehicle wireless CPU of the industrial vehicle remote control system acquires the received radio wave intensity of a remote control signal by which the two communication units wirelessly communicate, and, on the basis of the results thereof, determines whether the forklift is positioned in a permission range or in a prohibition range.

Abstract: Turbine housing assemblies and related turbocharger systems are provided. One exemplary turbine housing assembly includes an inner shell defining an inner inlet portion and a volute portion providing an outer contour of a volute, an outer shell surrounding the volute portion and defining an outer inlet portion circumscribing the inner inlet portion, and one or more energy absorbing members coupled to an inner surface of the outer shell between the outer shell and the inner shell. The inner shell includes a first plurality of sheet metal structures coupled together in a first plane and the outer shell includes a second plurality of sheet metal structures coupled together in a second plane transverse to the first plane.

Abstract: An editing apparatus includes a processor and a memory. The processor performs processes. The processes include causing a print image to be displayed in a first area, and a mark and at least one portion of a target character string to be displayed in a second area. The processes include causing a selection image to be displayed in a third area. The processes include performing a first determination whether a corresponding block included in the print image overlaps with the selection image. The processes include causing the entire corresponding block to be displayed in a first residual area. The processes include performing a second determination whether the mark overlaps with the selection image. The processes include reducing a size of the target character string. The processes include causing the mark and at least one portion of a reduced character string to be displayed in a second residual area.

Abstract: A forklift truck includes a two-dimensional rangefinder, a mover device, a calculator, and a determiner. The two-dimensional rangefinder emits a measurement wave in a downwardly inclined direction from above and toward a first load and measures a distance to a measurement point located on a surface of the first load. The mover device moves the two-dimensional rangefinder. The calculator calculates a longitudinal distance between the emitting source and the measurement point. The determiner determines that the first load is in a condition in which there is a level difference between a front part and a rear part of an upper surface of the first load, and the front part is higher than the rear part, when a variation in the longitudinal distance that is generated in response to a displacement of the two-dimensional rangefinder moved by the mover device exceeds an upper limit of a specified threshold range.

Abstract: An industrial vehicle remote operation system includes an industrial vehicle including a vehicle communication portion, a communication device, and, a first signal conversion portion. The communication device includes a reception portion that receives two or more types of operation signals, an obtainment portion that obtains a conversion program for converting the operation signal into the remote instruction signal, a storage portion configured to store the conversion program, a second signal conversion portion configured to convert the operation signal into the remote instruction signal using the conversion program, and a communication device communication portion that sends the remote instruction signal to the vehicle communication portion. The communication device includes an update portion configured to update information stored in the storage portion so as to enable addition, deletion, or change of one or more of the operation signals that are convertible by the second signal conversion portion.

Abstract: An editing apparatus includes a processor and a memory configured to store computer-readable instructions. The computer-readable instructions, when executed by the processor, cause the editing apparatus to perform processes that include causing a mark and at least one portion of a character string to be displayed, causing a selection image to be displayed in a state in which the at least one portion of the character string and the mark are displayed, performing, in a case where the selection image is displayed, a determination whether the mark ceases to be displayed in an outer side of one of a left edge and a right edge of the selection image, and moving the at least one portion of the character string and the mark to a position where the mark is displayed in the outer side, in response to determining that the mark ceases to be displayed in the outer side.

Abstract: Turbine housing assemblies and related turbocharger systems are provided. One exemplary turbine housing assembly includes an inner shell defining an inner inlet portion and a volute portion providing an outer contour of a volute, an outer shell surrounding the volute portion and defining an outer inlet portion circumscribing the inner inlet portion, and one or more energy absorbing members coupled to an inner surface of the outer shell between the outer shell and the inner shell. The inner shell includes a first plurality of sheet metal structures coupled together in a first plane and the outer shell includes a second plurality of sheet metal structures coupled together in a second plane transverse to the first plane.

Abstract: An optical signal repeater includes a plurality of ports, each configured to be connectable to both of a first optical transceiver for transmitting and receiving an optical signal to and from the optical line terminal and a second optical transceiver for transmitting and receiving an optical signal to and from the optical network unit. The optical signal repeater further includes a port switching control unit which switches each of the plurality of ports between a first port adapted to the first optical transceiver and a second port adapted to the second optical transceiver and a path switching unit configured to switch a transmission path between the plurality of ports. The path switching unit includes an aggregation unit configured to aggregate the transmission paths from the second ports. The optical signal repeater further includes a path switching control unit configured to control the path switching unit.

Abstract: A forklift truck includes a two-dimensional rangefinder, a mover device, a calculator, and a determiner. The two-dimensional rangefinder emits a measurement wave in a downwardly inclined direction from above and toward a first load and measures a distance to a measurement point located on a surface of the first load. The mover device moves the two-dimensional rangefinder. The calculator calculates a longitudinal distance between the emitting source and the measurement point. The determiner determines that the first load is in a condition in which there is a level difference between a front part and a rear part of an upper surface of the first load, and the front part is higher than the rear part, when a variation in the longitudinal distance that is generated in response to a displacement of the two-dimensional rangefinder moved by the mover device exceeds an upper limit of a specified threshold range.

Abstract: In a power converter, a housing is grounded. A power converter circuit is installed in the housing and configured to perform power conversion of input power into output power. An external terminal is electrically connected to the power converter circuit for connection of an external device to the power converter circuit. A first capacitor has first and second electrodes. The first electrode of the first capacitor is connected to the external terminal, and the second electrode thereof is connected to the housing. A second capacitor has first and second electrodes. The first electrode of the second capacitor is connected to the external terminal, and the second electrode thereof is connected to the housing. The first capacitor, the external terminal, the second capacitor, and the housing is arranged to provide a conductive loop.

Abstract: An optical signal repeater, an optical communication system, and a method of repeating an optical signal capable of decreasing a difference in transmission time period due to a difference in transmission distance of an optical signal between an optical line terminal and a plurality of optical network units connected through branched communication paths are provided. An optical signal repeat is an optical signal repeater for repeating an optical signal transmitted between an optical line terminal and a plurality of optical network units connected through branched communication paths. The optical signal repeater includes a delay element. The delay element is provided between the ONU connected to the OLT through a shortest communication path among the branched communication paths and the OLT and delays transmission of the optical signal transmitted through the shortest communication path.

Abstract: A noise filter is assembled to an electric power conversion device and has a metal housing casing and two capacitors connected to an external terminal of the device through which an electric power conversion circuit is connected to an external device. The two capacitors, the housing casing and the external terminal make a current loop. A magnetic flux of an alternating magnetic field generated in a part of the electric power conversion circuit penetrates in a first area and a second area formed in the current loop. A first induced noise current is induced in the current loop when the magnetic flux of the generated magnetic field penetrates in the first area. A second induced noise current is induced in the current loop when the magnetic flux penetrates in the second area so that the first induced noise current flows in a reverse direction to the second induced noise current.