Abstract: A workpiece processing apparatus comprises a base member, a slider located above the base member and a punch projecting downward from the slider. The base member is formed with a hydraulic chamber fillable with liquid. The hydraulic chamber has a workpiece processing chamber and a hydraulic-pressure generation chamber which are coupled together. Each of the workpiece processing chamber and the hydraulic-pressure generation chamber extends in the upper-lower direction and opens upward. The base member comprises a piston which is partially received in the hydraulic-pressure generation chamber. When the slider is moved downward, the punch is moved downward and presses the workpiece into the workpiece processing chamber, and the piston receives a downward force and is moved downward. The thus-moved piston increases hydraulic pressure of the liquid.

Abstract: A workpiece processing apparatus comprises a base member formed with a hydraulic chamber fillable with liquid, a punch and a piston. The hydraulic chamber has a workpiece processing chamber and a hydraulic-pressure generation chamber. The punch is movable between an initial position which is apart from the workpiece processing chamber and a received position at which the punch is partially received in the workpiece processing chamber. When the punch is moved from the initial position to the received position, the punch presses the workpiece into the workpiece processing chamber. The piston is partially received in the hydraulic-pressure generation chamber and receives a pressing force directed into the hydraulic-pressure generation chamber in a course of movement of the punch from the initial position to the received position, and the piston is moved in accordance with the pressing force and increases hydraulic pressure of the liquid.

Abstract: [Problems] The object is to provide a compound as a therapeutic or prophylactic agent for TKI-resistant CML to replace the injection “Dacogen®” which has been clinically used as a therapeutic agent for high-risk myelodysplastic syndrome and acute myeloid leukemia. The said compound has remarkable stability against cytidine deaminase, a hydrolytic enzyme, and is absorbed in vivo even by oral administration, incorporated into the biosynthesis route of nucleic acid, and exhibits the effect of inhibiting DNA methyltransferase (DNMT).

Abstract: Provided herein is a pharmaceutical composition for treating cancer, the pharmaceutical composition containing: a folic acid-modified hydroxyalkylated cyclodextrin selected from the group consisting of folic acid-modified hydroxypropylcyclodextrin, folic acid-modified hydroxybutylcyclodextrin, and folic acid-modified hydroxyethyl cyclodextrin; or a derivative thereof. Thus, a novel pharmaceutical composition for treating cancer and the like is provided.

Abstract: A power conversion apparatus, comprising: a semiconductor component for power conversion; a heat transfer member to which the semiconductor component is fixed such that the heat transfer member is thermally connected to a heat dissipation surface formed on at least one surface of the semiconductor component; and a housing, wherein the housing includes a heat dissipation wall portion, a fitting portion that fits to the heat transfer member is formed on the heat dissipation wall portion at an inside of the housing space, an area of contact between the fitting portion and the heat transfer member is greater than an area of the heat dissipation surface of the semiconductor component, and an occupied area of the fitting portion as seen in plan view is smaller than an area of the at least one surface of the semiconductor component on which the heat dissipation surface is formed.

Abstract: A cooling structure is provided. The cooling structure includes a harness, a board electrically connected to the harness, a heat transfer member whose one end is connected between the harness and the board, the heat transfer member being a member to which heat of the harness is transmitted, and a heat sink connected to the other end of the heat transfer member and configured to radiate heat transmitted to the heat transfer member.

Abstract: The present invention relates to an inhibitor against the stem cells of chronic myeloid leukemia (CML), a pharmaceutical composition for the treatment of CML having preventive effect on CML recurrence, a method of preventing CML recurrence, and a method of assessing the efficacy of treatment with a drug in a patient with CML, including a step of determining the expression level of latexin.

Abstract: This power supply device is provided with: a first heat-generating component; a case; a resin material; a circuit board; a second heat-generating component; and a heat dissipation casing. This power supply device is additionally provided with a heat transfer member which has a first portion that is arranged to be in contact with a first outer surface of the case and a second portion that is arranged to be in contact with a second outer surface of the case, and which has a higher thermal conductivity than the case. The second heat-generating component is arranged in contact with the heat transfer member; and the heat transfer member dissipates the heat of the first heat-generating component and the second heat-generating component by being arranged in contact with a wall surface that constitutes the heat dissipation casing.

Abstract: Provided is an equipment controlling apparatus that includes a storage section that stores a time frame within which a setting of operation of a device disposed in a predetermined region is to be changed, and a control section that controls the device to change operation between a time frame set in advance in the storage section and a time frame different from the time frame.

Abstract: This power supply device is provided with: a first heat-generating component; a case; a resin material; a circuit board; a second heat-generating component; and a heat dissipation casing. This power supply device is additionally provided with a heat transfer member which has a first portion that is arranged to be in contact with a first outer surface of the case and a second portion that is arranged to be in contact with a second outer surface of the case, and which has a higher thermal conductivity than the case. The second heat-generating component is arranged in contact with the heat transfer member; and the heat transfer member dissipates the heat of the first heat-generating component and the second heat-generating component by being arranged in contact with a wall surface that constitutes the heat dissipation casing.

Abstract: A power conversion apparatus, comprising: a semiconductor component for power conversion; a heat transfer member to which the semiconductor component is fixed such that the heat transfer member is thermally connected to a heat dissipation surface formed on at least one surface of the semiconductor component; and a housing, wherein the housing includes a heat dissipation wall portion, a fitting portion that fits to the heat transfer member is formed on the heat dissipation wall portion at an inside of the housing space, an area of contact between the fitting portion and the heat transfer member is greater than an area of the heat dissipation surface of the semiconductor component, and an occupied area of the fitting portion as seen in plan view is smaller than an area of the at least one surface of the semiconductor component on which the heat dissipation surface is formed.

Abstract: A power conversion apparatus, comprising: a semiconductor component for power conversion; a heat transfer member to which the semiconductor component is fixed such that the heat transfer member is thermally connected to a heat dissipation surface formed on at least one surface of the semiconductor component; and a housing, wherein the housing includes a heat dissipation wall portion, a fitting portion that fits to the heat transfer member is formed on the heat dissipation wall portion at an inside of the housing space, an area of contact between the fitting portion and the heat transfer member is greater than an area of the heat dissipation surface of the semiconductor component, and an occupied area of the fitting portion as seen in plan view is smaller than an area of the at least one surface of the semiconductor component on which the heat dissipation surface is formed.

Abstract: A power conversion device includes first and second components and pairs of engagement members each including male and female engagement members. The male engagement member includes an insertion part having a substantially flat plate shape. The female engagement member includes first and second clamping parts arranged to be opposed to each other. In each of the pairs of engagement members, the male and female engagement members are respectively arranged on one and another of the first and second components. The first and second components are coupled when the female engagement member clamps the insertion part inserted between the first and second clamping parts in each of the pairs of engagement members. Each of the first and second clamping parts is bent to form a projecting portion toward an opposed surface. A gap is provided at a distal end of each of the first and second clamping parts.

Abstract: A workpiece processing apparatus comprises a base member formed with a hydraulic chamber fillable with liquid, a punch and a piston. The hydraulic chamber has a workpiece processing chamber and a hydraulic-pressure generation chamber. The punch is movable between an initial position which is apart from the workpiece processing chamber and a received position at which the punch is partially received in the workpiece processing chamber. When the punch is moved from the initial position to the received position, the punch presses the workpiece into the workpiece processing chamber. The piston is partially received in the hydraulic-pressure generation chamber and receives a pressing force directed into the hydraulic-pressure generation chamber in a course of movement of the punch from the initial position to the received position, and the piston is moved in accordance with the pressing force and increases hydraulic pressure of the liquid.

Abstract: A workpiece processing apparatus comprises a base member, a slider located above the base member and a punch projecting downward from the slider. The base member is formed with a hydraulic chamber fillable with liquid. The hydraulic chamber has a workpiece processing chamber and a hydraulic-pressure generation chamber which are coupled together. Each of the workpiece processing chamber and the hydraulic-pressure generation chamber extends in the upper-lower direction and opens upward. The base member comprises a piston which is partially received in the hydraulic-pressure generation chamber. When the slider is moved downward, the punch is moved downward and presses the workpiece into the workpiece processing chamber, and the piston receives a downward force and is moved downward. The thus-moved piston increases hydraulic pressure of the liquid.