Patents by Inventor Shinya Yokosaka

Shinya Yokosaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic agent or preventive agent for alopecia areata
    Patent number: 10881649
    Abstract: A therapeutic agent or a preventive agent for alopecia areata has an ROR? antagonistic activity, and, there is a therapeutic agent or a preventive agent for alopecia areata, including a cyclic amine derivative typified by the following compound or a pharmacologically acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: January 5, 2021
    Assignee: Toray Industries, Inc.
    Inventors: Rie Sasaki, Shinnosuke Hayashi, Martial Vallet, Shinya Yokosaka, Kazuya Osumi, Takumi Aoki, Hiroyuki Meguro, Mie Kaino, Kozue Takagaki, Takehiro Takahashi
  • CYCLIC AMINE DERIVATIVE AND MEDICAL USE THEREOF
    Publication number: 20200392107
    Abstract: A cyclic amine derivative represented by general Formula (I): wherein R1 represents an alkyl group having 1 to 3 carbon atoms; A represents a group represented by general Formula (II-1), (II-2), or (II-3): R2 represents a hydrogen atom or a halogen atom; R3 represents an aryl group or a cycloalkyl group having 4 to 6 carbon atoms, wherein any 1 or 2 hydrogen atoms of the aryl or cycloalkyl group represented by R3 may be each independently substituted with an alkyl group having 1 to 3 carbon atoms or an alkyloxy group having 1 to 3 carbon atoms, and wherein any 1 to 3 hydrogen atoms of the alkyl or alkyloxy group having 1 to 3 carbon atoms which can be a substituent of the aryl or cycloalkyl group may be each independently substituted with a halogen atom; n represents 1 or 2; or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: January 30, 2019
    Publication date: December 17, 2020
    Inventors: Kazuya Osumi, Yuki Matsumura, Shinnosuke Hayashi, Masaki Hoshi, Martial Vallet, Shinya Yokosaka, Takumi Aoki, Hiroyuki Meguro, Mie Kaino, Kozuc Takagaki, Rie Sasaki
  • Peptide derivative and use thereof
    Patent number: 10792365
    Abstract: A peptide derivative represented by Formula (I) or a pharmaceutically acceptable salt thereof: wherein X represents an oxygen atom or NR, Y represents NH2, N(Me)H, SH, OH, or phenyl in which any one of hydrogen atoms is replaced by NH2 or OH, and R represents a hydrogen atom or C1-C3 alkyl, provided that the derivative where X is NH, and Y is NH2, and the derivative where X is NH, and Y is N(Me)H are excluded.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: October 6, 2020
    Assignee: Toray Industries, Inc.
    Inventors: Yukihiro Nishio, Shinya Yokosaka
  • THERAPEUTIC AGENT OR PREVENTIVE AGENT FOR ALOPECIA AREATA
    Publication number: 20200215046
    Abstract: A therapeutic agent or a preventive agent for alopecia areata has an ROR? antagonistic activity, and, there is a therapeutic agent or a preventive agent for alopecia areata, including a cyclic amine derivative typified by the following compound or a pharmacologically acceptable salt thereof as an active ingredient.
    Type: Application
    Filed: July 27, 2018
    Publication date: July 9, 2020
    Inventors: Rie Sasaki, Shinnosuke Hayashi, Martial Vallet, Shinya Yokosaka, Kazuya Osumi, Takumi Aoki, Hiroyuki Meguro, Mie Kaino, Kozue Takagaki, Takehiro Takahashi
  • Cyclic amine derivative and medical use thereof
    Patent number: 10364222
    Abstract: A compound has retinoid-related orphan receptor ? antagonist activity and shows a therapeutic effect or a preventive effect on autoimmune diseases such as multiple sclerosis or psoriasis or allergic diseases, including allergic dermatitis or the like, such as contact dermatitis or atopic dermatitis. The cyclic amine derivative is represented by the formula or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: July 30, 2019
    Assignee: Toray Industries, Inc.
    Inventors: Shinnosuke Hayashi, Martial Vallet, Shinya Yokosaka, Kazuya Osumi, Takumi Aoki, Hiroyuki Meguro, Mie Kaino, Kozue Takagaki, Takehiro Takahashi
  • PEPTIDE DERIVATIVE AND USE THEREOF
    Publication number: 20190038757
    Abstract: A peptide derivative represented by Formula (I) or a pharmaceutically acceptable salt thereof: wherein X represents an oxygen atom or NR, Y represents NH2, N(Me)H, SH, OH, or phenyl in which any one of hydrogen atoms is replaced by NH2 or OH, and R represents a hydrogen atom or C1-C3 alkyl, provided that the derivative where X is NH, and Y is NH2, and the derivative where X is NH, and Y is N(Me)H are excluded.
    Type: Application
    Filed: March 29, 2017
    Publication date: February 7, 2019
    Inventors: Yukihiro Nishio, Shinya Yokosaka
  • CYCLIC AMINE DERIVATIVE AND MEDICAL USE THEREOF
    Publication number: 20180370916
    Abstract: A compound has retinoid-related orphan receptor ? antagonist activity and shows a therapeutic effect or a preventive effect on autoimmune diseases such as multiple sclerosis or psoriasis or allergic diseases, including allergic dermatitis or the like, such as contact dermatitis or atopic dermatitis. The cyclic amine derivative is represented by the formula or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: January 27, 2017
    Publication date: December 27, 2018
    Inventors: Shinnosuke Hayashi, Martial Vallet, Shinya Yokosaka, Kazuya Osumi, Takumi Aoki, Hiroyuki Meguro, Mie Kaino, Kozue Takagaki, Takehiro Takahashi