Abstract: Microcapsules for effecting an immune response, especially through agglutination reaction, comprise an antigen or antibody bound to functional groups, such as amino groups, carboxy groups, etc., on a wall surface of the microcapsules via cross linking agents, such as polyfunctional isocyanates, isothiocyanates, etc. The antigen or antibody is strongly bound to the wall surface of the microcapsules to thereby achieve excellent detection sensitivity.

Abstract: A process for producing a microcapsule diagnostic material utilizing passive agglutination which comprises binding an antigen or antibody onto a microcapsule wall negatively charged, in an acidic solution is provided. The microcapsule diagnostic material thus produced has an extremely high sensitivity in agglutination without causing any non-specific agglutination.

Abstract: A photographic light-sensitive material comprising at least one hydrophilic colloid layer containing at least one dye represented by the following formula (I): ##SPC1##wherein R.sup.1 represents an alkyl group, a carboxy group, an alkoxycarbonyl group, a carbamoyl group, an alkylcarbamoyl group, a sulfamoyl group, an alkylsulfamoyl group, an acyl group, a hydroxy group, an alkoxy group, an alkylthio group, an amino group, a ureido group, an alkylureido group, a thioureido group or an alkylthioureido group; Q represents a sulfoalkyl group, a sulfoalkoxyalkyl group or a sulfoalkylthioalkyl group; L represents a methine group; n is 0 or 1; R.sup.2 represents --OR.sup.5 or ##EQU1## wherein R.sup.5, R.sup.6 and R.sup.7 each represents a hydrogen atom or an alkyl group; R.sup.3 represents a hydroxy group, an alkoxy group or an alkyl group; and R.sup.4 represents a hydrogen atom, an alkyl group, an alkoxy group, a sulfoalkoxy group, an alkylamino group or a dialkylamino group.