Abstract: A computer system that supports design for improving a function of a biological resource registers a history of the design, the history of the design including pair information of a related element related to a property of the biological resource and an operation on the related element, searches a database based on the pair information, acquires additional information other than the related element, the additional information being information related to the property of the biological resource based on a result of the search, computes a correlation of the additional information to the related element, and evaluates the additional information based on the calculated correlation.

Abstract: To predict a new biological reaction by quantifying while retaining characteristics of an entire compound structure. To provide a structural characteristic amount encoding unit that includes a conversion model unit configured to convert a characteristic amount of notation information indicating chemical structures of a plurality of compounds into a dispersedly represented numerical vector having at least two or more real number values as an element using a conversion parameter, the conversion model unit converting the characteristic amount of the notation information indicating the chemical structures into a numerical vector, for each of a first compound and a second compound among the plurality of compounds, and a biological reaction characteristic vector generator configured to generate a biological reaction characteristic vector between the first compound and the second compound by performing a calculation using a numerical vector of the first compound and a numerical vector of the second compound.