Patents by Inventor Shiping Cao
Shiping Cao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9429542Abstract: Embodiments of the present disclosure relate to substance detection technology, and to signal extraction circuits and methods for ion mobility tubes, and ion mobility detectors, which can solve the problem with the conventional technologies that it is difficult to design and manufacture the leadout circuit for the pulsed voltage on the Faraday plates. A signal extraction circuit for an ion mobility tube includes an DC-blocking module configured to remove a DC voltage contained in a voltage extracted, by a signal leadin terminal, from the Faraday plate, and to output, by a signal leadout terminal, a pulsed voltage contained in the voltage extracted from the Faraday plate. An ion mobility detector includes the signal extraction circuit for an ion mobility tube according to the present invention.Type: GrantFiled: December 28, 2012Date of Patent: August 30, 2016Assignees: Nuctech Company Limited, Tsinghua UniversityInventors: Qingjun Zhang, Zhiqiang Chen, Yuanjing Li, Ziran Zhao, Yinong Liu, Shiping Cao, Xiang Zou, Xianghua Li, Jianping Chang, Shuqiang Dong, Yan Zheng
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Patent number: 9285342Abstract: An ion mobility spectrometer system is disclosed. In one aspect, the system includes a gas chromatograph, first and second ion mobility spectrometers, and a sample feed device that feeds a sample from the gas chromatograph to the first and second ion mobility spectrometers. The sample feed device includes an inner chamber, first and second sample outlets for outputting the sample from the gas chromatograph to the first and second ion mobility spectrometers, respectively, and a gas inlet for inputting a gas into the sample feed device. The system detects and identifies molecules at improved resolution and enhanced molecule information. The system detects positive and negative ions, interrelates positive-mode and negative-mode spectrums, and separates substances.Type: GrantFiled: October 27, 2014Date of Patent: March 15, 2016Assignee: Nuctech Company LimitedInventors: Qingjun Zhang, Shiping Cao, Yuanjing Li, Zhiqiang Chen, Ziran Zhao, Yinong Liu, Jianping Chang, Yan Zheng, Yanchun Wang, Shaoji Mao
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Patent number: 9052284Abstract: The present invention discloses an asymmetric field ion mobility spectrometer. It comprises an ionization source, for generating ions; an electrode plate; a plurality of electrode filaments, arranged in opposite to and spaced apart from the electrode plate by an analysis gap, wherein a high voltage of electrical field is applied between the electrode plate and the electrode filaments to form an ion migration area, the electrode filaments used to collect the ions that do not pass through the ion migration area; and a collection electrode, disposed at a rear end of the ion migration area, and collecting the ions that have passed through the ion migration area. The present asymmetric field ion mobility spectrometer is capable of improving accuracy of identifying peak positions of the ions, reducing scanning time of DC voltage and types of compensation voltage, thereby increasing ion detection efficiency.Type: GrantFiled: December 28, 2012Date of Patent: June 9, 2015Assignee: Nuctech Company LimitedInventors: Shiping Cao, Qingjun Zhang, Zhiqiang Chen, Ziran Zhao, Yuanjing Li, Yinong Liu, Shuqiang Dong
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Publication number: 20150115152Abstract: An ion mobility spectrometer system is disclosed. In one aspect, the system includes a gas chromatograph, first and second ion mobility spectrometers, and a sample feed device that feeds a sample from the gas chromatograph to the first and second ion mobility spectrometers. The sample feed device includes an inner chamber, first and second sample outlets for outputting the sample from the gas chromatograph to the first and second ion mobility spectrometers, respectively, and a gas inlet for inputting a gas into the sample feed device. The system detects and identifies molecules at improved resolution and enhanced molecule information. The system detects positive and negative ions, interrelates positive-mode and negative-mode spectrums, and separates substances.Type: ApplicationFiled: October 27, 2014Publication date: April 30, 2015Inventors: Qingjun Zhang, Shiping Cao, Yuanjing Li, Zhiqiang Chen, Ziran Zhao, Yinong Liu, Jianpang Chang, Yan Zheng, Yanchun Wang, Shaoji Mao
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Publication number: 20140319337Abstract: The present invention discloses an asymmetric field ion mobility spectrometer. It comprises an ionization source, for generating ions; an electrode plate; a plurality of electrode filaments, arranged in opposite to and spaced apart from the electrode plate by an analysis gap, wherein a high voltage of electrical field is applied between the electrode plate and the electrode filaments to form an ion migration area, the electrode filaments used to collect the ions that do not pass through the ion migration area; and a collection electrode, disposed at a rear end of the ion migration area, and collecting the ions that have passed through the ion migration area. The present asymmetric field ion mobility spectrometer is capable of improving accuracy of identifying peak positions of the ions, reducing scanning time of DC voltage and types of compensation voltage, thereby increasing ion detection efficiency.Type: ApplicationFiled: December 28, 2012Publication date: October 30, 2014Inventors: Shiping Cao, Qingjun Zhang, Zhiqiang Chen, Ziran Zhao, Yuanjing Li, Yinong Liu, Shuqiang Dong
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Publication number: 20130313426Abstract: Embodiments of the present disclosure relate to substance detection technology, and to signal extraction circuits and methods for ion mobility tubes, and ion mobility detectors, which can solve the problem with the conventional technologies that it is difficult to design and manufacture the leadout circuit for the pulsed voltage on the Faraday plates. A signal extraction circuit for an ion mobility tube includes an DC-blocking module configured to remove a DC voltage contained in a voltage extracted, by a signal leadin terminal, from the Faraday plate, and to output, by a signal leadout terminal, a pulsed voltage contained in the voltage extracted from the Faraday plate. An ion mobility detector includes the signal extraction circuit for an ion mobility tube according to the present invention.Type: ApplicationFiled: December 28, 2012Publication date: November 28, 2013Applicant: Tsinghua UniversityInventors: Qingjun Zhang, Zhiqiang Chen, Yuanjing Li, Ziran Zhao, Yinong Liu, Shiping Cao, Xiang Zou, Xianghua Li, Jianping Chang, Shuqiang Dong, Yan Zheng
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Patent number: 8362422Abstract: The present invention discloses a sample feeding device for an ion mobility spectrometer, which is adapted to guide a sample to be detected into an inlet of a drift tube of the ion mobility spectrometer.Type: GrantFiled: April 27, 2011Date of Patent: January 29, 2013Assignees: Nuctech Company Limited, Tsinghua UniversityInventors: Qingjun Zhang, Zhiqiang Chen, Shiping Cao, Yuanjing Li, Ziran Zhao, Yinong Liu, Yan Zheng, Shaoji Mao, Xiang Zou, Jianping Chang
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Patent number: 8288718Abstract: An ion mobility spectrometer comprises an electrode and two storage electrodes disposed at the two opposite sides of the electrode respectively. Ions from an intermediate part between the two storage electrodes are stored and the stored ions are released from the storage electrodes by changing electric potentials of the two storage electrodes. The present invention further discloses a detecting method using an ion mobility spectrometer.Type: GrantFiled: June 28, 2010Date of Patent: October 16, 2012Assignee: Nuctech Company LimitedInventors: Yuanjing Li, Zhiqiang Chen, Qingjun Zhang, Shiping Cao, Dexu Lin, Shaoji Mao, Qinghua Wang
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Patent number: 8278627Abstract: A sample feeding device for a trace detector is disclosed. The sample feeding device comprises: a sample feeding chamber disposed in the sample feeding device to desorb a sample from a sample feeding member; and a valve assembly configured to fluidly communicate the sample feeding chamber with a drift tube of the trace detector during feeding sample. With the above configuration of the present invention, for example, the sensitivity of the detector can be increased by improving the permeation ratio of the sample. In addition, interior environment of the drift tube is isolated from exterior environment to avoid a drift region of the drift tube from being polluted. The important parameters, such as sensitivity, a position of a peak of a substance, a resolution, of the detector can be kept constant. As a result, operation reliability and consistency of the detector can be achieved.Type: GrantFiled: May 16, 2011Date of Patent: October 2, 2012Assignees: Nuctech Company Limited, Tsinghua UniversityInventors: Yuanjing Li, Zhiqiang Chen, Qingjun Zhang, Shaoji Mao, Ziran Zhao, Yinong Liu, Shiping Cao, Yan Zheng, Jianping Chang, Xiang Zou
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Patent number: 8217365Abstract: Disclosed is an ion source comprising a plate-shaped source body which has radioactivity on its both sides and allows positive and negative ions to penetrate through the source body. The present invention gives beneficial effects. First, the ion source structure can improve the ionization efficiency of sample molecules, and the generated sample ions have a centralized distribution within a flat space on both sides of the source body. Such distribution of ion cloud facilitates to improve the IMS sensitivity. Meanwhile, the source body of the present invention has a transmittance in itself. Thus, positive and negative ions generated on both sides of the source body can penetrate through the source body and be separated to the both sides of the source body. In this way, it is possible to improve the utilization efficiency of ions.Type: GrantFiled: May 7, 2009Date of Patent: July 10, 2012Assignee: Nuctech Company LimitedInventors: Zhiqiang Chen, Yuanjing Li, Hua Peng, Qingjun Zhang, Jin Lin, Shaoji Mao, Zhude Dai, Shiping Cao, Zhongxia Zhang, Yangtian Zhang, Dexu Lin, Qinghua Wang, Shaofeng Wang, Hui Li
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Publication number: 20120168616Abstract: The present invention discloses a sample feeding device for an ion mobility spectrometer, which is adapted to guide a sample to be detected into an inlet of a drift tube of the ion mobility spectrometer.Type: ApplicationFiled: April 27, 2011Publication date: July 5, 2012Inventors: Qingjun Zhang, Zhiqiang Chen, Shiping Cao, Yuanjing Li, Ziran Zhao, Yinong Liu, Yan Zheng, Shaoji Mao, Xiang Zou, Jianping Chang
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Publication number: 20120168620Abstract: A sample feeding device for a trace detector is disclosed. The sample feeding device comprises: a sample feeding chamber disposed in the sample feeding device to desorb a sample from a sample feeding member; and a valve assembly configured to fluidly communicate the sample feeding chamber with a drift tube of the trace detector during feeding sample. With the above configuration of the present invention, for example, the sensitivity of the detector can be increased by improving the permeation ratio of the sample. In addition, interior environment of the drift tube is isolated from exterior environment to avoid a drift region of the drift tube from being polluted. The important parameters, such as sensitivity, a position of a peak of a substance, a resolution, of the detector can be kept constant. As a result, operation reliability and consistency of the detector can be achieved.Type: ApplicationFiled: May 16, 2011Publication date: July 5, 2012Inventors: Yuanjing Li, Zhiqiang Chen, Qingjun Zhang, Shaoji Mao, Ziran Zhao, Yinong Liu, Shiping Cao, Yan Zheng, Jianping Chang, Xiang Zou
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Patent number: 8013297Abstract: Disclosed is an ion gate for a dual IMS and method. The ion gate includes an ion source, a first gate electrode placed on one side of the ion source, a second gate electrode placed on the other side of the ion source, a third gate electrode placed on the side of the first gate electrode away from the ion source, a fourth gate electrode placed on the side of the second gate electrode away from the ion source, wherein during the ion storage, the potential at the position on the tube axis of the ion gate corresponding to the first gate electrode is different from the potentials at the positions on the tube axis corresponding to the ion source and the third gate electrode, and the potential at the position on the tube axis corresponding to the second gate electrode is different from the potentials at the positions on the tube axis corresponding to the ion source and the fourth gate electrode.Type: GrantFiled: October 15, 2009Date of Patent: September 6, 2011Assignees: Nuctech Company Limited, Tsinghua UniversityInventors: Hua Peng, Qingjun Zhang, Jin Lin, Yuanjing Li, Zhiqiang Chen, Shaoji Mao, Zhude Dai, Dai Hua, legal representative, Shiping Cao, Zhongxia Zhang, Yangtian Zhang, Dexu Lin, Qinghua Wang
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Publication number: 20110133072Abstract: An ion mobility spectrometer comprises an electrode and two storage electrodes disposed at the two opposite sides of the electrode respectively. Ions from an intermediate part between the two storage electrodes are stored and the stored ions are released from the storage electrodes by changing electric potentials of the two storage electrodes. The present invention further discloses a detecting method using an ion mobility spectrometer.Type: ApplicationFiled: June 28, 2010Publication date: June 9, 2011Inventors: Yuanjing Li, Zhiqiang Chen, Qingjun Zhang, Shiping Cao, Dexu Lin
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Patent number: 7851747Abstract: Disclosed is an electrode structure for a drift tube in IMS comprising a ring electrode, for each of two surfaces of the ring electrode, at least a part adjacent to the inner radius is formed into a cone, and the angles formed between the cones and the axis of the ring electrode are different from each other. The electrode structure of the present invention can alleviate, even eliminate, the accumulation of space charges in the drift tube. Such structure is particularly suitable when the electric field in the drift tube is low in strength or a great number of ions pass through. Meanwhile, the structure allows a significant decrease in the size of the outer radius of the electrode, while the inner radius remains constant. In this way, it is possible to effectively reduce the outline size of the drift tube and thus make the IMS compact.Type: GrantFiled: May 27, 2009Date of Patent: December 14, 2010Assignees: Nuctech Company Limited, Tsinghua UniversityInventors: Zhiqiang Chen, Yuanjing Li, Hua Peng, Qingjun Zhang, Jin Lin, Shaoji Mao, Zhude Dai, Shiping Cao, Zhongxia Zhang, Yangtian Zhang, Dexu Lin, Qinghua Wang, Shaofeng Wang, Hui Li
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Publication number: 20100102219Abstract: Disclosed is an ion gate for a dual IMS and method. The ion gate includes an ion source, a first gate electrode placed on one side of the ion source, a second gate electrode placed on the other side of the ion source, a third gate electrode placed on the side of the first gate electrode away from the ion source, a fourth gate electrode placed on the side of the second gate electrode away from the ion source, wherein during the ion storage, the potential at the position on the tube axis of the ion gate corresponding to the first gate electrode is different from the potentials at the positions on the tube axis corresponding to the ion source and the third gate electrode, and the potential at the position on the tube axis corresponding to the second gate electrode is different from the potentials at the positions on the tube axis corresponding to the ion source and the fourth gate electrode.Type: ApplicationFiled: October 15, 2009Publication date: April 29, 2010Inventors: Hua Peng, Qingjun Zhang, Jin Lin, Yuanjing Li, Zhiqiang Chen, Shaoji Mao, Zhude Dai, Shiping Cao, Zhongxia Zhang, Yangtian Zhang, Dexu Lin, Qinghua Wang, Zhang Qing Jun
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Publication number: 20090309013Abstract: Disclosed is an electrode structure for a drift tube in IMS comprising a ring electrode, for each of two surfaces of the ring electrode, at least a part adjacent to the inner radius is formed into a cone, and the angles formed between the cones and the axis of the ring electrode are different from each other. The electrode structure of the present invention can alleviate, even eliminate, the accumulation of space charges in the drift tube. Such structure is particularly suitable when the electric field in the drift tube is low in strength or a great number of ions pass through. Meanwhile, the structure allows a significant decrease in the size of the outer radius of the electrode, while the inner radius remains constant. In this way, it is possible to effectively reduce the outline size of the drift tube and thus make the IMS compact.Type: ApplicationFiled: May 27, 2009Publication date: December 17, 2009Applicants: Nuctech Company Limited, Tsinghua UniversityInventors: Zhiqiang Chen, Yuanjing Li, Hua Peng, Qingjun Zhang, Jin Lin, Shaoji Mao, Zhude Dai, Shiping Cao, Zhongxia Zhang, Yangtian Zhang, Dexu Lin, Qinghua Wang, Shaofeng Wang, Hui Li
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Publication number: 20090283694Abstract: Disclosed is an ion source comprising a plate-shaped source body which has radioactivity on its both sides and allows positive and negative ions to penetrate through the source body. The present invention gives beneficial effects. First, the ion source structure can improve the ionization efficiency of sample molecules, and the generated sample ions have a centralized distribution within a flat space on both sides of the source body. Such distribution of ion cloud facilitates to improve the IMS sensitivity. Meanwhile, the source body of the present invention has a transmittance in itself. Thus, positive and negative ions generated on both sides of the source body can penetrate through the source body and be separated to the both sides of the source body. In this way, it is possible to improve the utilization efficiency of ions.Type: ApplicationFiled: May 7, 2009Publication date: November 19, 2009Inventors: Zhiqiang CHEN, Yuanjing LI, Hua PENG, Qingjun ZHANG, Jin LIN, Shaoji MAO, Zhude DAI, Shiping CAO, Zhongxia ZHANG, Yangtian ZHANG, Dexu LIN, Qinghua WANG, Shaofeng WANG, Hui LI