Abstract: The present invention relates to the technical field of medicine, and particularly to a lycorine derivative of Formula (I), and a pharmaceutically acceptable salt, a preparation method, a pharmaceutical composition and use thereof. The lycorine derivative has obvious antiviral activity and is useful in the treatment of viral diseases such as hand-foot-mouth disease.

Abstract: An ore dressing process for medium-grade and low-grade mixed collophanite includes the following steps: S1; crushing ores to obtain crushed ores; S2: screening the crushed ores to obtain fine-fraction ores and coarse-fraction ores divided into at least two size fractions; S3: performing a photoelectric separation to the coarse-fraction ores of different size fractions to obtain photoelectric separation concentrates and photoelectric separation tailings of each size fraction; S4: combining the photoelectric separation concentrates of the each size fraction to obtain pre-enriched concentrates; S5: combining the fine-fraction ores and the pre-enriched concentrates, and then performing an ore grinding to obtain minerals to be separated; S6: adding water to the minerals to be separated to obtain a floatation pulp, and then performing a floatation to obtain phosphate concentrates and tailings.

Abstract: A lycorine derivative of Formula (I), and a pharmaceutically acceptable salt, a preparation method, a pharmaceutical composition and use thereof wherein the lycorine derivative has obvious antiviral activity and is useful in the treatment of viral diseases such as hand-foot-mouth disease.