Abstract: A molding device and a molding method for an optical fiber preform are provided. The molding device includes a rotating mechanism, an extrusion mechanism, and a cylinder mold that is of a cylindrical structure with two ends each having an opening. After a hollow cladding sleeve is obtained by rotating the cylinder mold through the rotating mechanism, a molten core glass is then reversely extruded into the cladding sleeve in the cylinder mold from bottom to top by the extrusion mechanism to prepare the optical fiber preform.

Abstract: Provided is an application of a BAZ2B gene as a target in slowing aging. It is disclosed that the BAZ2B gene plays an important regulatory role in occurrence and development of normal aging and age-related diseases, and the down-regulation thereof can significantly slow aging and alleviate memory decay, capacity degradation and the like in the aging process. The BAZ2B can be used as the research target of aging and age-related diseases for developing drugs of inhibiting or delaying aging, and used as a diagnostic and prognostic marker of aging and age-related diseases.