Patents by Inventor Shirley A. Pomponi

Shirley A. Pomponi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biologically active aphrocallistin compounds
    Patent number: 8058430
    Abstract: The subject invention provides novel compositions of biologically active compounds which can advantageously be used in blocking cellular proliferation and/or treatment of cancer.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: November 15, 2011
    Assignee: Florida Atlantic University Broad of Trustees
    Inventors: Amy E. Wright, Susan H. Sennett, Shirley A. Pomponi, Peter J. McCarthy, Esther A. Guzman
  • Biologically active lasonolide compounds
    Patent number: 7521474
    Abstract: The subject invention provides novel compositions of biologically active macrolide compounds which can advantageously be used in blocking cellular proliferation, treatment of cancer, treatment of fungal infections and control of spoilage of food, cosmetic and other consumer items.
    Type: Grant
    Filed: July 27, 2006
    Date of Patent: April 21, 2009
    Assignee: Florida Atlantic University Board of Trustees
    Inventors: Amy E. Wright, Shirley A. Pomponi, Peter J. McCarthy, Ying Chen, Ross E. Longley
  • Biologically Active Aphrocallistin Compounds
    Publication number: 20090005400
    Abstract: The subject invention provides novel compositions of biologically active compounds which can advantageously be used in blocking cellular proliferation and/or treatment of cancer.
    Type: Application
    Filed: June 30, 2008
    Publication date: January 1, 2009
    Inventors: Amy E. Wright, Susan H. Sennett, Shirley A. Pomponi, Peter J. McCarthy, Esther A. Guzman
  • Methods for extending the life span of marine invertebrate cells
    Publication number: 20070254367
    Abstract: The subject invention provides materials and methods for extending the life span and/or immortalizing marine invertebrate cell lines. Specifically exemplified herein are methods for extending the life spans for sponges, cnidarians, mollusks and ascidians. In a preferred embodiment exemplified herein, the cells whose lives are extended are marine sponge cells.
    Type: Application
    Filed: April 30, 2007
    Publication date: November 1, 2007
    Inventors: Shirley Pomponi, Jane Thompson, James Bottesch, Susan Sennett
  • Biologically active neopeltolide compounds
    Patent number: 7179828
    Abstract: The subject invention provides novel compositions of biologically active macrolide compounds which can advantageously be used in blocking cellular proliferation, treatment of cancer, treatment of fungal infections and control of spoilage of food, cosmetic and other consumer items.
    Type: Grant
    Filed: June 22, 2004
    Date of Patent: February 20, 2007
    Inventors: Amy E. Wright, Shirley A. Pomponi, Peter J. McCarthy
  • Novel biologically active lasonolide compounds
    Publication number: 20060264499
    Abstract: The subject invention provides novel compositions of biologically active macrolide compounds which can advantageously be used in blocking cellular proliferation, treatment of cancer, treatment of fungal infections and control of spoilage of food, cosmetic and other consumer items.
    Type: Application
    Filed: July 27, 2006
    Publication date: November 23, 2006
    Inventors: Amy Wright, Shirley Pomponi, Peter McCarthy, Ying Chen, Ross Longley
  • Analysis and modification of gene expression in marine invertebrate cells
    Patent number: 7135292
    Abstract: The subject invention identifies changes in gene expression related to treatment of marine invertabret cell cultures.
    Type: Grant
    Filed: June 30, 2003
    Date of Patent: November 14, 2006
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Robin Willoughby, Shirley A. Pomponi
  • Biologically active lasonolide compounds
    Patent number: 7115756
    Abstract: The subject invention provides novel compositions of biologically active macrolide compounds which can advantageously be used in blocking cellular proliferation, treatment of cancer, treatment of fungal infections and control of spoilage of food, cosmetic and other consumer items.
    Type: Grant
    Filed: June 23, 2004
    Date of Patent: October 3, 2006
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Amy E. Wright, Shirley A. Pomponi, Peter J. McCarthy, Ying Chen, Ross E. Longley
  • Biologically active raspailamide compounds
    Patent number: 7094803
    Abstract: The subject invention provides novel compositions of biologically active polyketide compounds that can advantageously be used in blocking cellular proliferation and treatment of cancer.
    Type: Grant
    Filed: July 12, 2004
    Date of Patent: August 22, 2006
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: K. Brian Killday, Amy E. Wright, Shirley A. Pomponi, Ross E. Longley
  • Biologically active raspailamide compounds
    Publication number: 20050038106
    Abstract: The subject invention provides novel compositions of biologically active polyketide compounds that can advantageously be used in blocking cellular proliferation and treatment of cancer.
    Type: Application
    Filed: July 12, 2004
    Publication date: February 17, 2005
    Inventors: K. Killday, Amy Wright, Shirley Pomponi, Ross Longley
  • Novel biologically active lasonolide compounds
    Publication number: 20050009901
    Abstract: The subject invention provides novel compositions of biologically active macrolide compounds which can advantageously be used in blocking cellular proliferation, treatment of cancer, treatment of fungal infections and control of spoilage of food, cosmetic and other consumer items.
    Type: Application
    Filed: June 23, 2004
    Publication date: January 13, 2005
    Inventors: Amy Wright, Shirley Pomponi, Peter McCarthy, Ying Chen, Ross Longley
  • Biologically active neopeltolide compounds
    Publication number: 20040266847
    Abstract: The subject invention provides novel compositions of biologically active macrolide compounds which can advantageously be used in blocking cellular proliferation, treatment of cancer, treatment of fungal infections and control of spoilage of food, cosmetic and other consumer items.
    Type: Application
    Filed: June 22, 2004
    Publication date: December 30, 2004
    Inventors: Amy E. Wright, Shirley A. Pomponi, Peter J. McCarthy
  • Discorhabdin compounds and methods of use
    Patent number: 6835736
    Abstract: The subject invention provides novel compositions of biologically active discorhabdin compounds which can advantageously be used for inhibiting pathological cellular proliferation. The compounds of the subject invention have utility for use in the treatment of cancer, including tumors.
    Type: Grant
    Filed: February 28, 2003
    Date of Patent: December 28, 2004
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Sarath P. Gunasekera, Ross E. Longley, Shirley A. Pomponi, Amy E. Wright
  • Analysis and modification of gene expression in marine invertebrate cells
    Publication number: 20040063119
    Abstract: The subject invention identifies changes in gene expression related to treatment of marine invertabret cell cultures.
    Type: Application
    Filed: June 30, 2003
    Publication date: April 1, 2004
    Inventors: Robin Willoughby, Shirley A. Pomponi
  • Compositions and uses of dictyostatin compounds
    Patent number: 6677370
    Abstract: Dictyostatin-1 has been found to stabilize microtubules and prohibit their depolymerization to free tubulin. Because of these activities, the dictyostatin compounds can be used in the treatment of a number of diseases in which aberrant cellular proliferation occurs such as drug-sensitive and drug-resistant cancers, autoimmune disorders, and inflammatory diseases.
    Type: Grant
    Filed: February 6, 2003
    Date of Patent: January 13, 2004
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Amy E. Wright, Jennifer L. Cummins, Shirley A. Pomponi, Ross E. Longley, Richard A. Isbrucker
  • Novel compositions and uses of dictyostatin compounds
    Publication number: 20030153615
    Abstract: Dictyostatin-1 has been found to stabilize microtubules and prohibit their depolymerization to free tubulin. Because of these activities, the dictyostatin compounds can be used in the treatment of a number of diseases in which aberrant cellular proliferation occurs such as drug-sensitive and drug-resistant cancers, autoimmune disorders, and inflammatory diseases.
    Type: Application
    Filed: February 6, 2003
    Publication date: August 14, 2003
    Inventors: Amy E. Wright, Jennifer L. Cummins, Shirley A. Pomponi, Ross E. Longley, Richard A. Isbrucker
  • Anti-inflammatory uses of manzamines
    Patent number: 6602881
    Abstract: The subject invention pertains to compounds which are useful as anti-inflammatory agents and to compositions containing such compounds as active ingredients. The novel uses of the compounds relate to the anti-neurogenic inflammatory properties of the disclosed compounds. Specifically exemplified herein is the use of manzamines A, B, C, D, E, and F, and their salts, analogs, and derivatives.
    Type: Grant
    Filed: May 13, 2002
    Date of Patent: August 5, 2003
    Assignee: Harbor Branch Oceanograhic Institution, Inc.
    Inventors: Alejandro Mayer, Sarath P. Gunasekera, Shirley A. Pomponi, Susan H. Sennett
  • Compounds and methods of use for treatment of neurogenic inflammation
    Patent number: 6589957
    Abstract: The subject invention pertains to compounds which are useful as anti-inflammatory agents and to compositions containing such compounds as active ingredients. The novel uses of the compounds relate to the anti-neurogenic inflammatory properties of the disclosed bis-heterocyclic compounds. Specifically exemplified herein are dragmacidin f, topsentin d, and topsentin e, and their salts, analogs, and derivatives.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: July 8, 2003
    Assignees: Harbor Branch Oceanographic Institution, Inc., Regents of the University of California
    Inventors: Amy E. Wright, Shirley A. Pomponi, Robert S. Jacobs
  • Compositions and uses of dictyostatin compounds
    Patent number: 6576658
    Abstract: Dictyostatin-1 has been found to stabilize microtubules and prohibit their depolymerization to free tubulin. Because of these activities, the dictyostatin compounds can be used in the treatment of a number of diseases in which aberrant cellular proliferation occurs such as drug-sensitive and drug-resistant cancers, autoimmune disorders, and inflammatory diseases.
    Type: Grant
    Filed: February 26, 2001
    Date of Patent: June 10, 2003
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Amy E. Wright, Jennifer L. Cummins, Shirley A. Pomponi, Ross E. Longley, Richard A. Isbrucker
  • Cyclic peroxides as novel antifungal agents
    Patent number: 6521661
    Abstract: The novel compositions and methods of the subject invention can be used in antifugal applications. The antifugal agents of the subject invention can be used in the treatment of an animal or human having a fugal infection. In a further embodiment the compounds can be used to treat plant fugal infections, disinfect surfaces, and prevent spoilage of organic compositions such as food and cosmetics.
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: February 18, 2003
    Assignees: Harbor Branch Oceanographic Institution, Inc., Mycologics, Inc.
    Inventors: Ying Chen, Katherine Chilson, Keith Brian Killday, Dedra Harmody, Peter J. McCarthy, Shirley A. Pomponi, Rebecca Schimoler, Claude Selitrennikoff, Amy E. Wright