Abstract: Methods and apparatus provide filtration for concentrating analytes, such as bacteria or exosomes, of a biological sample, such as blood or urine. The technology may employ membrane devices that implement one or more tangential flow filtration processes such as in stages. An example membrane device may typically include a membrane having sides and ends. The membrane may selectively permit constituent(s) of the sample to pass through while retaining other constituents at one side. An input chamber of the device may include an inlet near one end and an outlet near the other end, and that may permit a tangential flow of the sample along the first side surface, and a trans-membrane passing of constituent(s). An output chamber of the device may be configured at the second side surface to receive the passing constituents. Such devices may be provided in a kit to facilitate targeting of a desired biological analyte concentration.

Abstract: This invention relates to the clear, substantially anhydrous, warming compositions containing one or more polyhydric alcohols. The invention also relates to the compositions that include at least one or more antioxidant or antioxidants in combination selected from the group consisting of tocopherol, ascorbic acid and butylated hydroxytoluene (BHT), to prevent oxidation of polyhydric alcohol combination that results in the development of odor.

Abstract: A semiconductor package is disclosed. In one embodiment the package includes a semiconductor chip including an active surface with a plurality of chip contact areas and a package substrate including a plurality of first contact areas and a plurality of second contact areas on its bottom surface. The chip is mounted on the package substrate with its active surface facing the package substrate. A plurality of conducting means provide electrical contact between the chip contact areas and the first contact areas. A heat spreading means comprises a planar area and at least one protrusion. The planar area is attached to the upper surface of the chip and the protrusion is attached to the upper surface of the package substrate.

Abstract: This invention relates to the clear, substantially anhydrous, warming compositions containing one or more polyhydric alcohols. The invention also relates to the compositions that include at least one or more antioxidant or antioxidants in combination selected from the group consisting of tocopherol, ascorbic acid and butylated hydroxytoluene (BHT), to prevent oxidation of polyhydric alcohol combination that results in the development of odor.