Patents by Inventor Shirong Li

Shirong Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240016843
    Abstract: A CAR-immunocyte targeting an NKG2D ligand can be used in the preparation of a drug. The drug is used for: (i) removing the senescent cell, the NKG2D ligand in the senescent cell being up-regulated by 2-20 times, preferably 4-15 times, more preferably 10-20 times the normal cell; (ii) delaying individual senescence; and/or (iii) preventing and/or treating age-related diseases. The CAR-immunocyte targeting the NKG2D ligand is capable of specifically removing the senescent cell having high expression of the NKG2D ligand, and has higher in-vivo security.
    Type: Application
    Filed: December 2, 2021
    Publication date: January 18, 2024
    Inventors: Xudong ZHAO, Dong YANG, Shirong LI
  • Publication number: 20230330196
    Abstract: Immunosuppressive peptide fragments of MMP-13, pharmaceutical compositions comprising said peptides, and methods of inhibiting T cell proliferation.
    Type: Application
    Filed: May 2, 2023
    Publication date: October 19, 2023
    Inventors: Suzanne Lentzsch, Shirong Li, Jing Fu, Markus Y. Mapara, Hui-Hui Ma
  • Publication number: 20230092728
    Abstract: Compounds and methods for treatment of cancers such as multiple myeloma by inhibition of germinal center kinase.
    Type: Application
    Filed: August 24, 2022
    Publication date: March 23, 2023
    Inventors: Suzanne Lentzsch, Shirong Li, Jing Fu, Donald W. Landry, Shixian Deng, Xiaoming Xu