Abstract: Provided herein are methods, systems, and compositions for determining a base in a polynucleotide. In various aspects, the methods, systems, and compositions presented herein are useful for performing 4-base, 5-base, or 6-base sequencing of polynucleotide molecules, for example, from liquid biopsy samples or wherein the base is a low frequency mutation.

Abstract: The present disclosure provides a quantum dot particle aggregate and a preparation method therefor, a preparation method for a light conversion device, and quantum dot particles. The preparation method for the quantum dot particle aggregate includes: mixing a plurality of first polymer particles, a first quantum dot solution and a second polymer solution, and drying to obtain an aggregate containing a plurality of quantum dot particles A, where each of the quantum dot particles A includes a core of a first polymer particle and a shell of a second polymer formed by the second polymer, a plurality of first quantum dots are positioned in the shell of the second polymer, and the first polymer particle has a minimum dimension greater than or equal to 0.3 mm. The process reduces the damage to quantum dots and can prolong the life time of application products of quantum dots.

Abstract: Provided herein are systems and methods for detection of an epigenetic modification in a nucleic acid sequence. The systems and methods as described herein may provide a substantially unbiased approach in detecting an epigenetic modification. The systems and method as described herein may provide a substantially unbiased approach in detecting an epigenetic modification in comparison to systems and methods that amplify sequences having a label or a moiety associated with an epigenetic modification.

Abstract: Provided herein are methods, systems, and compositions for determining a base in a polynucleotide. In various aspects, the methods, systems, and compositions presented herein are useful for performing 4-base, 5-base, or 6-base sequencing of polynucleotide molecules, for example, from liquid biopsy samples or wherein the base is a low frequency mutation.

Abstract: Disclosed are a light conversion device and a preparation method thereof, and a display device having the light conversion device. The preparation method includes the step of performing photolithography process n times on the substrate layer sequentially, wherein a patterned quantum dot structure and a cured photoresist layer are obtained by means of this step.

Abstract: Provided herein are methods, systems, and compositions for determining a base in a polynucleotide. In various aspects, the methods, systems, and compositions presented herein are useful for performing 4-base, 5-base, or 6-base sequencing of polynucleotide molecules, for example, from liquid biopsy samples or wherein the base is a low frequency mutation.

Abstract: Provided herein are methods, systems, and compositions for determining a base in a polynucleotide. In various aspects, the methods, systems, and compositions presented herein are useful for performing 4-base, 5-base, or 6-base sequencing of polynucleotide molecules, for example, from liquid biopsy samples or wherein the base is a low frequency mutation.

Abstract: The present application discloses a display substrate. The display substrate includes a base substrate; a color filter on the base substrate; and an overcoat layer on a side of the color filter distal to the base substrate. The overcoat layer includes a first sublayer and a second sublayer, the second sublayer on a side of the first sublayer distal to the base substrate. The first sublayer includes a first polymer material. The second sublayer includes a second polymer material different from the first polymer material.

Abstract: A touch panel comprises a first substrate (1), a second substrate (2) opposite to the first substrate (1), and spacers (5) between the first substrate (1) and the second substrate (2). At least one of the spacers (5) comprises a piezoelectric material. The piezoelectric material is a graphene-polyborosiloxane composite.

Abstract: The present application discloses a display substrate. The display substrate includes a base substrate; a color filter on the base substrate; and an overcoat layer on a side of the color filter distal to the base substrate. The overcoat layer includes a first sublayer and a second sublayer, the second sublayer on a side of the first sublayer distal to the base substrate. The first sublayer includes a first polymer material. The second sublayer includes a second polymer material different from the first polymer material.

Abstract: A touch panel comprises a first substrate (1), a second substrate (2) opposite to the first substrate (1), and spacers (5) between the first substrate (1) and the second substrate (2). At least one of the spacers (5) comprises a piezoelectric material. The piezoelectric material is a graphene-polyborosiloxane composite.

Abstract: The embodiments of the present disclosure provide a base plate, a manufacturing method thereof and a display panel, relating to the field of display technology. Ink droplets in grooves defined by a pixel defining layer can be spread uniformly, thereby effectively improving the product quality and the display effect. The base plate comprises a substrate and a pixel defining layer arranged on the substrate, wherein the pixel defining layer comprises dams and several micron-sized protrusions arranged on the upper surfaces and sides of the dams; and the protrusions have lyophobic property.

Abstract: The embodiments of the disclosure relate to a proximity exposure device and an exposure method thereof. The proximity exposure device includes: a loading table; a holder mounted onto the loading table to hold a mask; a vacuum hood arranged above the mask to form a sealed space above the mask; and a pumping mechanism connected to the vacuum hood to pump air from the vacuum hood such that a negative pressure state is formed above the mask.

Abstract: The embodiments of the present disclosure provide a base plate, a manufacturing method thereof and a display panel, relating to the field of display technology. Ink droplets in grooves defined by a pixel defining layer can be spread uniformly, thereby effectively improving the product quality and the display effect. The base plate comprises a substrate and a pixel defining layer arranged on the substrate, wherein the pixel defining layer comprises dams and several micron-sized protrusions arranged on the upper surfaces and sides of the dams; and the protrusions have lyophobic property.

Abstract: The present invention provides a method for preparing high-strength cross-linked polymer photonic crystal film by core-shell polymer microspheres via evaporation-induced self assembly. Monodispersed core-shell polymer microspheres are fabricated by emulsifier-free emulsion polymerization, and then the microspheres emulsion is coated onto suitable substrates. Finally, polymer photonic crystal film with long-range ordered is constructed via self assembly. Self-cross-linking between the two units improves the strength of the polymer photonic crystal film, therefore the preparation of large size industrial-grade photonic crystal film is practicable which extends its application on the field of dyeing.

Abstract: The embodiments of the disclosure relate to a proximity exposure device and an exposure method thereof. The proximity exposure device includes: a loading table; a holder mounted onto the loading table to hold a mask; a vacuum hood arranged above the mask to form a sealed space above the mask; and a pumping mechanism connected to the vacuum hood to pump air from the vacuum hood such that a negative pressure state is formed above the mask.

Abstract: The present invention provides a method for preparing high-strength cross-linked polymer photonic crystal film by core-shell polymer microspheres via evaporation-induced self assembly. Monodispersed core-shell polymer microspheres are fabricated by emulsifier-free emulsion polymerization, and then the microspheres emulsion is coated onto suitable substrates. Finally, polymer photonic crystal film with long-range ordered is constructed via self assembly. Self-cross-linking between the two units improves the strength of the polymer photonic crystal film, therefore the preparation of large size industrial-grade photonic crystal film is practicable which extends its application on the field of dyeing.